Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
Stephen H. Caldwell, Saumya Jayakumar, Anna Mae Diehl, G. Mani Subramanian, Ling Han, John G. McHutchison, Zachary Goodman, Nezam H. Afdhal, C. Stephen Djedjos, Eric Lawitz, Parvez S. Mantry, Rohit Loomba, Hays Arnold, Robert P. Myers, Michael Charlton
Publikováno v:
Hepatology. 67:549-559
Inhibition of apoptosis signal-regulating kinase 1, a serine/threonine kinase, leads to improvement in inflammation and fibrosis in animal models of nonalcoholic steatohepatitis. We evaluated the safety and efficacy of selonsertib, a selective inhibi
Autor:
Xiao-Fan Wang, Bin Yang, Wenhao Qin, Anna Mae Diehl, Gregory A. Michelotti, Qi-Jing Li, Geoffrey J. Markowitz, Rui Chen, Jianhua Sui, Zheng Zhang, Jing Fu, Fu-Sheng Wang, Hongyang Wang, Pengyuan Yang
Publikováno v:
Cancer Research. 76:2394-2405
Chronic inflammation in liver tissue is an underlying cause of hepatocellular carcinoma. High levels of inflammatory cytokine IL18 in the circulation of patients with hepatocellular carcinoma correlates with poor prognosis. However, conflicting resul
Autor:
Cynthia D. Guy, Lixin Zhu, Ruixin Zhu, Patrizia Farci, Wensheng Liu, Sugantha Govindarajan, Fausto Zamboni, Dingfeng Wu, Susan S. Baker, Zhiwei Cao, Anna Mae Diehl, Manal F. Abdelmalek, Cynthia A. Moylan, Robert D. Baker, Weili Lin
Publikováno v:
The Journal of Pathology. 238:531-542
Obese animals and non-alcoholic fatty liver disease (NAFLD) patients exhibit elevated blood alcohol, suggesting potential contributions of alcohol metabolism to the development of NAFLD. Liver gene expression in patients with biopsy-proven mild (N =
Autor:
Richard T. Premont, Mariana Verdelho Machado, Thiago A. Pereira, Anna Mae Diehl, Guanhua Xie, Helena Cortez-Pinto, Gregory A. Michelotti
Publikováno v:
Journal of Hepatology. 63:962-970
Background & Aims Mechanisms that regulate regeneration of injured livers are complex. YAP, a stem cell associated factor, controls liver growth in healthy adult mice. Increasing nuclear localization of YAP triggers accumulation of reactive-appearing
Autor:
Thiago A. Pereira, Isaac S. Chan, Márcia Maria de Souza, Wing-Kin Syn, Vivian Resende, Steve S. Choi, Alba Otoni, Mariana Verdelho Machado, Anna Mae Diehl, Guilherme Vaz de Melo Trindade, Paula Vieira Teixeira Vidigal, Elisângela Trindade Santos, Izabela Voieta, William Evan Secor, Rafal P. Witek, Zilton A. Andrade, José Roberto Lambertucci, Guanhua Xie, Fausto Edmundo Lima Pereira
Publikováno v:
Clinical Science (London, England : 1979)
Schistosomal egg antigens induce host bile ductular cells to proliferate and produce osteopontin (OPN), a pro-fibrogenic factor that stimulates hepatic stellate cells to become myofibroblasts. The numbers of OPN-producing bile ductules correlate with
Publikováno v:
Journal of Hepatology. 70:e782-e783
Autor:
Ann O. Scheimann, Emily R. Perito, Jean P. Molleston, Jeffrey B. Schwimmer, Katherine P. Yates, Veeral Ajmera, Nathan M. Bass, Karen F. Murray, David V. Glidden, Bradley E. Aouizerat, Ryan M. Gill, Anna Mae Diehl, Philip J. Rosenthal, Joel E. Lavine
Publikováno v:
Hepatology Communications, vol 1, iss 7
Hepatology Communications
Hepatology Communications
Author(s): Perito, Emily R; Ajmera, Veeral; Bass, Nathan M; Rosenthal, Philip; Lavine, Joel E; Schwimmer, Jeffrey B; Yates, Katherine P; Diehl, Anna Mae; Molleston, Jean P; Murray, Karen F; Scheimann, Ann; Gill, Ryan; Glidden, David; Aouizerat, Bradl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc138c4deb5cd509ef99545484dfd72
https://escholarship.org/uc/item/8cv9c55d
https://escholarship.org/uc/item/8cv9c55d
Autor:
Cynthia A. Moylan, Anikia Tucker, Heather A. Himburg, Cynthia D. Guy, Erik J. Soderblom, Mariana Verdelho Machado, Leandi Krüger, Richard T. Premont, Katherine S. Garman, J. Will Thompson, Meredith Mayer-Salman, John P. Chute, Steve S. Choi, Gregory A. Michelotti, Anna Mae Diehl, Marzena Swiderska-Syn
Publikováno v:
Gut
Objective The ductular reaction (DR) involves mobilisation of reactive-appearing duct-like cells (RDC) along canals of Hering, and myofibroblastic (MF) differentiation of hepatic stellate cells (HSC) in the space of Disse. Perivascular cells in stem
Publikováno v:
Hepatology. 61:98-107
Hedgehog (Hh) ligand production by ballooned hepatocytes drives nonalcoholic steatohepatitis (NASH) progression in mice. The NIDDK-sponsored PIVENS trial (NCT00063622) showed that vitamin E (VitE) improved NASH. We investigated whether VitE treatment
Autor:
Anna Mae Diehl, Dawn Piercy, Cynthia D. Guy, Yuval A. Patel, Cynthia A. Moylan, Manal F. Abdelmalek, Ricardo Henao
The pathogenesis of nonalcoholic fatty liver disease (NAFLD) is complex. Vitamin D (VitD) has been implicated in NAFLD pathogenesis because it has roles in immune modulation, cell differentiation and proliferation, and regulation of inflammation. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aca54c58429db57249034383d971123
https://europepmc.org/articles/PMC5331905/
https://europepmc.org/articles/PMC5331905/