Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Adrian M. Owen"'
Autor:
Erind Alushaj, Nicholas Handfield-Jones, Alan Kuurstra, Anisa Morava, Ravi S. Menon, Adrian M. Owen, Manas Sharma, Ali R. Khan, Penny A. MacDonald
Publikováno v:
NeuroImage: Clinical, Vol 41, Iss , Pp 103577- (2024)
Degeneration in the substantia nigra (SN) pars compacta (SNc) underlies motor symptoms in Parkinson’s disease (PD). Currently, there are no neuroimaging biomarkers that are sufficiently sensitive, specific, reproducible, and accessible for routine
Externí odkaz:
https://doaj.org/article/39dfea95398a48f3919a91ed6410283b
Autor:
Michael J. Firbank, Tien K. Khoo, Brit Mollenhauer, Elijah Mak, Rachael A Lawson, David J. Burn, James B. Rowe, Guy B. Williams, Alison J. Yarnall, John T. O'Brien, David J. Brooks, Roger A. Barker, Gordon W Duncan, Adrian M. Owen, Li Su
Publikováno v:
Mak, E, Su, L, Williams, G B, Firbank, M J, Lawson, R A, Yarnall, A J, Duncan, G W, Mollenhauer, B, Owen, A M, Khoo, T K, Brooks, D J, Rowe, J B, Barker, R A, Burn, D J & O'Brien, J T 2017, ' Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease ', Neurobiology of Aging, vol. 55, pp. 78-90 . https://doi.org/10.1016/j.neurobiolaging.2017.03.012
Brain and Mind Institute Researchers' Publications
Neurobiology of Aging
Brain and Mind Institute Researchers' Publications
Neurobiology of Aging
We investigated whole-brain atrophy and ventricular enlargement over 18 months in nondemented Parkinson's disease (PD) and examined their associations with clinical measures and baseline CSF markers. PD subjects (n = 100) were classified at baseline
Publikováno v:
BrainsCAN Publications
Polish Psychological Bulletin, Vol 47, Iss 1, Pp 123-130 (2016)
Polish Psychological Bulletin, Vol 47, Iss 1, Pp 123-130 (2016)
© Polish Academy of Sciences, Committee for Psychological Sciences 2016. Idiopathic Parkinson's disease (PD) impairs working memory, but the exact nature of this deficit in terms of the underlying cognitive mechanisms is not well understood. In this
Autor:
Nole M. Hiebert, Adrian M. Owen, Mary E. Jenkins, Penny A. MacDonald, Daniel Mendonca, Hooman Ganjavi, Ken N. Seergobin
Publikováno v:
Brain and Mind Institute Researchers' Publications
© 2018 Learning associations between stimuli and responses is essential to everyday life. Dorsal striatum (DS) has long been implicated in stimulus-response learning, though recent results challenge this contention. We have proposed that discrepant
Autor:
Elijah Mak, Michael J. Firbank, James B. Rowe, Thais Minett, David J. Brooks, Roger A. Barker, Rachael A Lawson, John T. O'Brien, Alison J. Yarnall, Gordon W Duncan, David J. Burn, Adrian M. Owen, Li Su, Guy B. Williams, Tien K. Khoo
Publikováno v:
Brain and Mind Institute Researchers' Publications
Minett, T, Su, L, Mak, E, Williams, G, Firbank, M, Lawson, R A, Yarnall, A J, Duncan, G W, Owen, A M, Khoo, T K, Brooks, D J, Rowe, J B, Barker, R A, Burn, D & O'Brien, J T 2018, ' Longitudinal diffusion tensor imaging changes in early Parkinson's disease : ICICLE-PD study ', Journal of Neurology, vol. 265, no. 7, pp. 1528-1539 . https://doi.org/10.1007/s00415-018-8873-0
Minett, T, Su, L, Mak, E, Williams, G, Firbank, M, Lawson, R A, Yarnall, A J, Duncan, G W, Owen, A M, Khoo, T K, Brooks, D J, Rowe, J B, Barker, R A, Burn, D & O'Brien, J T 2018, ' Longitudinal diffusion tensor imaging changes in early Parkinson's disease : ICICLE-PD study ', Journal of Neurology, vol. 265, no. 7, pp. 1528-1539 . https://doi.org/10.1007/s00415-018-8873-0
Objective: To investigate whether white matter microstructural changes can be used as a predictor of worsening of motor features or cognitive decline in patients with Parkinson’s disease and verify whether white matter microstructural longitudinal
Autor:
Penny A. MacDonald, Nole M. Hiebert, Andrew Vo, Adam Hampshire, Ken N. Seergobin, Adrian M. Owen
Publikováno v:
Brain and Mind Institute Researchers' Publications
Cognitive deficits are recognized in Parkinson's disease. Understanding cognitive functions mediated by the striatum can clarify some of these impairments and inform treatment strategies. The dorsal striatum, a region impaired in Parkinson's disease,
Autor:
Roger A. Barker, James B. Rowe, John T. O'Brien, Elijah Mak, Alison J. Yarnall, David J. Brooks, Rachael A Lawson, Guy B. Williams, Tien K. Khoo, David J. Burn, Michael J. Firbank, Li Su, Gordon W Duncan, Adrian M. Owen, Thais Minett
Publikováno v:
Alzheimer's & Dementia. 13
Publikováno v:
Brain and Mind Institute Researchers' Publications
Cognitive deficits are a frequent symptom of Parkinson's disease (PD), particularly in the domain of spatial working memory (WM). Despite numerous demonstrations of aberrant WM in patients, there is a lack of understanding about how, if at all, their
Publikováno v:
Brain and Mind Institute Researchers' Publications
Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Impaired ability to shift attention between stimuli (i.e. shifting attentional ‘set’) is a well-established part of the dysexecutive syndrome in Parkinson's Disease (PD), nevertheless cognitive and neural bases of this deficit remain unclear. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27d3867b72f8fbde4a0b069e34d0111
https://ruj.uj.edu.pl/xmlui/handle/item/47819
https://ruj.uj.edu.pl/xmlui/handle/item/47819
Publikováno v:
Brain and Mind Institute Researchers' Publications
Impaired attentional flexibility is considered to be one of the core cognitive deficits in Parkinson's disease (PD). However, the mechanisms that underlie this impairment are contested. Progress in resolving this dispute has also been hindered by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4c89680f8156f5d9bdcb789b0a7d0d
https://ir.lib.uwo.ca/brainpub/981
https://ir.lib.uwo.ca/brainpub/981