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Toxoplasma gondii has long been considered a ubiquitous parasite possessing the capacity of infecting virtually all warm-blooded animals globally. Occasionally, this parasite can also infect cold-blooded animals such as fish if their body temperature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a4da6357a9d7470605d272c8ce388c
https://usir.salford.ac.uk/id/eprint/58025/1/1-s2.0-S0014489420302034-main.pdf
https://usir.salford.ac.uk/id/eprint/58025/1/1-s2.0-S0014489420302034-main.pdf
Publikováno v:
Journal of affective disorders. 250
Introduction and Aim: Toxoplasma gondii is an intracellular protozoan parasite infecting approximately 30% of the global human population. It has often been suggested that chronic infection with T. gondii is related to personality changes and various
Autor:
Francisco J. Ayala, Weijun Huang, Xiaoyong Chen, Geoff Hide, Andy Peng Xiang, De-Hua Lai, Zhao-Rong Lun, Aiping Qin, Huimin Xia, Sunxing Yan, Qifa Liu, Ya-Ping Wu
Publikováno v:
Qin, A; Lai, D-H; Liu, Q; Huang, W; Wu, Y-P; Chen, X; et al.(2017). Guanylate-binding protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against Toxoplasma gondii. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(6), 1365-1370. doi: 10.1073/pnas.1619665114. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/21s583gj
Mesenchymal stromal cells (MSCs) have recently been shown to play important roles in mammalian host defenses against intracellular pathogens, but the molecular mechanism still needs to be clarified. We confirmed that human MSCs (hMSCs) prestimulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95dd374837377978b6aa667d722345a9
Autor:
Sameena Z.H. Haq, Omar Gerwash, Mohamed S. Elmahaishi, Zhao-Rong Lun, J. M. Hughes, Geoff Hide, Denise Thomasson, Muftah S. Abushahama, Elizabeth A. Wright
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 110(9)
Background:\ud Toxoplasma gondii is a parasite that causes significant disease in humans. Toxoplasmosis is normally asymptomatic, unless associated with congenital transmission, or in immunocompromised people. Congenital transmission generally occurs
Autor:
Qingli Luo, Yong Wang, Wen-jian Song, Li Yu, Zhao-Rong Lun, Jilong Shen, Aimei Zhang, Yuansheng Hu, Fangli Lu, Tingting Liu, Lili Liu, Yihong Cai, Xiucai Xu
Publikováno v:
Foodborne Pathogens and Disease. 9:7-12
Toxoplasma gondii infections are prevalent in a wide range of mammalian hosts including humans. Infection in pregnant women may cause the transmission of parasite to the fetus that makes serious problems. IgM antibodies against Toxoplasma (Toxo-IgM)
Autor:
Ling-Ling Zheng, Geoff Hide, Liang-Hu Qu, Ting-Bo Yang, Yan-Zi Wen, Wen-Liang Zhou, Francisco J. Ayala, Zhao-Rong Lun, De-Hua Lai, Jilong Shen
Publikováno v:
Lun, ZR; Lai, DH; Wen, YZ; Zheng, LL; Shen, JL; Yang, TB; et al.(2015). Cancer in the parasitic protozoans Trypanosoma brucei and Toxoplasma gondii. Proceedings of the National Academy of Sciences of the United States of America, 112(29), 8835-8842. doi: 10.1073/pnas.1502599112. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2wf4g187
Proceedings of the National Academy of Sciences of the United States of America, vol 112, iss 29
Proceedings of the National Academy of Sciences of the United States of America, vol 112, iss 29
Cancer is a general name for more than 100 malignant diseases. It is postulated that all cancers start from a single abnormal cell that grows out of control. Untreated cancers can cause serious consequences and deaths. Great progress has been made in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44a9b59f7c91f07b84cbee61619093f
http://www.escholarship.org/uc/item/2wf4g187
http://www.escholarship.org/uc/item/2wf4g187
Autor:
Wen-Liang Zhou, Zhao-Rong Lun, Jiang-Mei Gao, Yan-Zi Wen, Yi-Lin Zhang, Hong-Mei Guo, Yu-Li Luo, Francisco J. Ayala, Geoff Hide
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 112, iss 14
Guo, HM; Gao, JM; Luo, YL; Wen, YZ; Zhang, YL; Hide, G; et al.(2015). Infection by Toxoplasma gondii, a severe parasite in neonates and AIDS patients, causes impaired anion secretion in airway epithelia. Proceedings of the National Academy of Sciences of the United States of America, 112(14), 4435-4440. doi: 10.1073/pnas.1503474112. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5kt4d6pq
Guo, HM; Gao, JM; Luo, YL; Wen, YZ; Zhang, YL; Hide, G; et al.(2015). Infection by Toxoplasma gondii, a severe parasite in neonates and AIDS patients, causes impaired anion secretion in airway epithelia. Proceedings of the National Academy of Sciences of the United States of America, 112(14), 4435-4440. doi: 10.1073/pnas.1503474112. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5kt4d6pq
The airway epithelia initiate and modulate the inflammatory responses to various pathogens. The cystic fibrosis transmembrane conductance regulator-mediated Cl- secretion system plays a key role in mucociliary clearance of inhaled pathogens. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92005879c1196bdecd800cebe8cfcbcf
https://escholarship.org/uc/item/5kt4d6pq
https://escholarship.org/uc/item/5kt4d6pq
Publikováno v:
Cell Biology International. 30:149-153
The influence of insulin and 2-deoxy-glucose (D-glucose) on the intracellular protozoan Toxoplasma gondii replication in 3T3-L1 cells was investigated. Insulin and D-glucose had a dose-responsive mitogenic effect on intracellular T. gondii replicatio
Autor:
Barbara Tschirren, M.T. Rogan, Geoff Hide, Jennifer Morger, Philip S. Craig, Jaroslav Bajnok, Zhao-Rong Lun, K. Boyce
Publikováno v:
Infection Genetics and Evolution
Toxoplasma gondii is a highly successful parasite with a worldwide prevalence. Small rodents are the main intermediate hosts, and there is growing evidence that T. gondii modifies their behaviour. Chronically infected rodents show impaired learning c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59fb5e8f5fc00cbee1bcb01adced3e6
https://doi.org/10.5167/uzh-98299
https://doi.org/10.5167/uzh-98299
Publikováno v:
Protein Expression and Purification. 23:33-37
Surface antigen 1 (SAG1) of Toxoplasma gondii is a good candidate for diagnosis and vaccine development, but recombinant SAG1 produced in Escheichia coli often loses its specific immunogenicity due to the incorrect folding. In the present study, a tr