Zobrazeno 31 - 40
of 40
pro vyhledávání: '"Pablo Muriel"'
Autor:
Víctor Tsutsumi, Erika Hernández-Aquino, Pablo Muriel, Natanael Zarco, José Segovia, Erika Ramos-Tovar, Sael Casas-Grajales, Mineko Shibayama, Rosa E. Flores-Beltrán, Jonathan Arauz, Liliana Favari
Publikováno v:
World Journal of Gastroenterology
AIM To study the molecular mechanisms involved in the hepatoprotective effects of naringenin (NAR) on carbon tetrachloride (CCl4)-induced liver fibrosis. METHODS Thirty-two male Wistar rats (120-150 g) were randomly divided into four groups: (1) a co
Autor:
J Eliuth, Pérez-Vargas, Natanael, Zarco, Mineko, Shibayama, José, Segovia, Víctor, Tsutsumi, Pablo, Muriel
Publikováno v:
Pharmacology. 94(1-2)
To evaluate the antioxidant, immunomodulatory, antinecrotic and antifibrotic effects of hesperidin on CCl4-induced cirrhosis.Liver damage was produced by giving CCl4 injections (0.4 g/kg, i.p., 3 times per week for 8 weeks) to rats. Hesperidin (200 m
Autor:
Jonathan Arauz, Mineko Shibayama, Pablo Muriel, Natanael Zarco, Víctor Tsutsumi, José Segovia
Publikováno v:
European journal of gastroenterologyhepatology. 26(2)
There is a growing body of evidence that caffeine exerts beneficial effects on the liver; however, the molecular mechanisms by which caffeine exerts beneficial effects on the liver are poorly defined.The aim of the present study was to examine the ef
Autor:
Pablo Muriel, Liseth R. Aldaba-Muruato, Mario G. Moreno, Elisa Hernández-Mercado, Mineko Shibayama
Publikováno v:
Canadian journal of physiology and pharmacology. 90(11)
Allopurinol is an inhibitor of xanthine oxidase (XO), and XO is an enzyme that generates great amounts of reactive oxygen species. The aim of this work was to evaluate the efficacy of allopurinol to prevent experimental cirrhosis. Fibrosis and cirrho
Autor:
Liseth R, Aldaba-Muruato, Mario G, Moreno, Mineko, Shibayama, Víctor, Tsutsumi, Pablo, Muriel
Publikováno v:
Pharmacology. 92(3-4)
Allopurinol is an inhibitor of xanthine oxidase. The aim of this work was to evaluate the efficacy of allopurinol to reverse the experimental cirrhosis induced by CCl4. Rats received CCl4 for 8 weeks, and immediately after allopurinol was administere
Publikováno v:
Fundamentalclinical pharmacology. 27(3)
Several studies suggest that free radicals may play a role in cholestatic liver injury. The aim of this work was to evaluate the role of trolox in chronic bile duct ligation (BDL). Liver injury was induced by 28-day BDL to male Wistar rats. Animals w
Publikováno v:
Biochimica et biophysica acta. 1820(2)
Background The aim of this work was to evaluate the hepatoprotective ability of allopurinol to prevent the liver injury induced by carbon tetrachloride (CCl 4 ). Methods Acute liver damage was induced with CCl 4 (4 g/kg, by gavage); allopurinol (50 m
Autor:
Pablo Muriel
Publikováno v:
Hepatology international. 3(4)
Reactive oxygen and nitrogen species (ROS and RNS) are produced by metabolism of normal cells. However, in liver diseases, redox is increased thereby damaging the hepatic tissue; the capability of ethanol to increase both ROS/RNS and peroxidation of
Autor:
Pablo, Muriel, Mario G, Moreno
Publikováno v:
Basicclinical pharmacologytoxicology. 94(2)
Oxidative stress, in particular lipid peroxidation, induces collagen synthesis. Thus, we administered various antioxidants to bile duct-ligated rats for 28 days and lipid peroxidation, glutathione content, fibrosis, necrosis and cholestasis were eval
Autor:
Verónica Barón, Pablo Muriel
Publikováno v:
Biochimica et biophysica acta. 1472(1-2)
The aim of this work was to evaluate the role of lipid peroxidation and glutathione on liver damage induced by 7-day biliary obstruction in the rat. Male Wistar rats were bile-duct-ligated and divided in groups of 10 animals. Groups received vitamin
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