Zobrazeno 1 - 10
of 11
pro vyhledávání: '"João Pedro Silva"'
Autor:
Helena Carmo, Félix Carvalho, Maria de Lourdes Bastos, Rita Roque Bravo, Maria João Valente, Diana Silva, João Pedro Silva
Publikováno v:
Archives of Toxicology. 95:1443-1462
Synthetic cathinones are among the most popular new psychoactive substances, being abused for their stimulant properties, which are similar to those of amphetamine and 3,4-methylenedioxymethamphetamine (MDMA). Considering that the liver is a likely t
Autor:
Morsyleide de Freitas Rosa, Pedro Ferreirinha, Ricardo Silva-Carvalho, F. Miguel Gama, Manuel Vilanova, João Pedro Silva, Alexandre F. Leitão, Cecília Cristelo, Fábia Karine Andrade, Rui Costa
Publikováno v:
Toxicological Research
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
In view of the growing industrial use of Bacterial cellulose (BC), and taking into account that it might become airborne and be inhaled after industrial processing, assessing its potential pulmonary toxic effects assumes high relevance. In this work,
Autor:
João Pedro Silva, Helena Carmo, Maria de Lourdes Bastos, Maria João Valente, Félix Carvalho, Rita Roque Bravo, Diana Silva
Publikováno v:
Archives of toxicology. 94(2)
New phenylethylamine derivatives are among the most commonly abused new psychoactive substances. They are synthesized and marketed in lieu of classical amphetaminic stimulants, with no previous safety testing. Our study aimed to determine the in vitr
Autor:
Félix Carvalho, Rita Roque Bravo, Maria de Lourdes Bastos, Helena Carmo, João Pedro Silva, Diana Silva, Maria João Valente
Publikováno v:
Toxicology. 463:152988
4-Fluoromethamphetamine (4-FMA) is an amphetamine-like psychoactive substance with recognized entactogenic and stimulant effects, but hitherto unclear toxicological mechanisms. Taking into consideration that the vast majority of 4-FMA users consume t
Autor:
Monika Garcia, Miguel Gama, Manuela Martins-Green, João Pedro Silva, César Costa, Sandeep Dhall, Alex Chan
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Antimicrobial peptides (AMPs) are good candidates to treat burn wounds, a major cause of morbidity, impaired life quality and resources consumption in developed countries. We took advantage of a commercially available hydrogel, Carbopol, a vehicle fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14208869b1f18bd9b83e78d1aaa78a2e
https://escholarship.org/uc/item/4fj3r2xm
https://escholarship.org/uc/item/4fj3r2xm
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Biological systems are frequently exposed to excessive reactive oxygen species, causing a disturbance in the cells natural antioxidant defence systems and resulting in damage to all biomolecules, including nucleic acids. In fact, oxidative DNA damage
Autor:
Manuela Martins-Green, Sandeep Dhall, Ronald J. Neufeld, Monika Garcia, João Pedro Silva, Alex Chan, Julia G. Lyubovitsky, Yan Liu, Michael Hrynyk
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Clinical science (London, England : 1979), vol 129, iss 12
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Clinical science (London, England : 1979), vol 129, iss 12
Burn wound healing involves a complex set of overlapping processes in an environment conducive to ischemia, inflammation, and infection costing $7.5 billion/year in the US alone, in addition to the morbidity and mortality that occur when the burns ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd06c0be977b08d50a19159c1a6e7d4
https://hdl.handle.net/1822/38236
https://hdl.handle.net/1822/38236
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
In this study we used new nitrogen compounds obtained by organic synthesis whose structure predicted an antioxidant potential and then an eventual development as molecules of pharmacological interest in diseases involving oxidative stress. The compou
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Oxidative DNA damage has been described as an important type of damage that occurs in neuronal cells, with severe implications in many neurodegenerative diseases and in aging. We have previously reported the protection of four new synthetic nitrogen
Autor:
Maria João R. P. Queiroz, Olga P. Coutinho, Diana Pinto-Basto, João Pedro Silva, Antonio Moreno
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
We investigated the antioxidant properties of two synthetic diarylamines, MJQ1 and MJQ2. For one of them (MJQ1) the synthesis procedure is herein described. The compounds showed maximal protection of ADP/Fe(2+) induced mitochondrial lipid peroxidatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f55a7c3f917d9ed063feb68f2ffade