Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yachun Han"'
Publikováno v:
Current Medicinal Chemistry. 28:1003-1024
Diabetic nephropathy (DN) is one of the most common and important microvascular complications of diabetes mellitus (DM). The main clinical features of DN are proteinuria and a progressive decline in renal function, which are associated with structura
Publikováno v:
Current Medicinal Chemistry
Background: Kidney disease is a serious problem that adversely affects human health, but critical knowledge is lacking on how to effectively treat established chronic kidney disease. Mounting evidence from animal and clinical studies has suggested th
Autor:
Ling Wei, Yachun Han, Jinfei Yang, Xuejing Zhu, Xi Wang, Ming Yang, Chenrui Li, Lin Sun, Wei Chen
Publikováno v:
Current medicinal chemistry. 28(42)
Diabetic nephropathy (DN) is one of the most common complications of diabetes and the main cause of end-stage renal disease (ESRD). The inflammatory response plays a key role in the pathological process of DN. As the most deeply studied inflammasome,
Autor:
Chengyuan Tang, Xiaofen Xiong, Xiaoxuan Xu, Lin Sun, Shuguang Yuan, Yachun Han, Xianghui Chen, Shikun Yang, Yashpal S. Kanwar, Fuyou Liu, Xuejing Zhu, Ming Yang, Li Xiao, Peng Gao
Publikováno v:
Redox Biology
Redox Biology, Vol 16, Iss, Pp 32-46 (2018)
Redox Biology, Vol 16, Iss, Pp 32-46 (2018)
NLRP3/IL-1β activation via thioredoxin (TRX)/thioredoxin-interacting protein (TXNIP) following mitochondria ROS (mtROS) overproduction plays a key role in inflammation. However, the involvement of this process in tubular damage in the kidneys of pat
Autor:
Yachun Han, Chun Hu, Chao Chen, Lin Sun, Fuyou Liu, Li Xiao, Xuejing Zhu, Li Zhao, Yu Liu, Shikun Yang, Yashpal S. Kanwar, Ming Zhan, Zhiguang Zhou, Xiaofen Xiong
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 482-497 (2017)
Redox Biology
Redox Biology
Aims Probucol is an anti-hyperlipidemic agent and a potent antioxidant drug that can delay progression of diabetic nephropathy (DN) and reverses renal oxidative stress in diabetic animal models; however, the mechanisms underlying these effects remain
Autor:
Fuyou Liu, Chao Chen, Yachun Han, Xuejing Zhu, Yashpal S. Kanwar, Xiaofen Xiong, Lin Sun, Shikun Yang, Chun Hu, Li Zhao, Yu Liu, Li Xiao, Ming Zhan, Zhiguang Zhou
Publikováno v:
Redox Biology
Probucol is an anti-hyperlipidemic agent and a potent antioxidant drug that can delay progression of diabetic nephropathy (DN) and reverses renal oxidative stress in diabetic animal models; however, the mechanisms underlying these effects remain uncl
Autor:
Yachun Han, Li Xiao, Shuguang Yuan, Ming Yang, Peng Gao, Shikun Yang, X. Chen, Xiaoxuan Xu, Chengyuan Tang, Fuyou Liu, Xuejing Zhu, Yashpal S. Kanwar, Xiaofen Xiong, Lin Sun
NLRP3/IL-1β activation via thioredoxin (TRX)/thioredoxin-interacting protein (TXNIP) following mitochondria ROS (mtROS) overproduction plays a key role in inflammation. However, the involvement of this process in tubular damage in the kidneys of pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec42301de5d0631c1e4fca2dc0411e7
https://europepmc.org/articles/PMC6597693/
https://europepmc.org/articles/PMC6597693/
Autor:
Jun Liu, Shikun Yang, Pan-ai Song, Xiaoxuan Xu, Yachun Han, Chun Hu, Li Xiao, Lin Sun, Li Zhao, Fuyou Liu, Hao Zhang
Publikováno v:
Current medicinal chemistry. 24(29)
Diabetic nephropathy (DN) is an important diabetic microvascular complication, and it is becoming the leading cause of end-stage renal disease worldwide. Unfortunately, there are no effective therapies to treat established DN. Therefore, new therapeu
Autor:
Xiao Fu, Lin Sun, Shikun Yang, Yinghong Liu, Li Xiao, Fuyou Liu, Chun Hu, Xiaofen Xiong, Xiaoxuan Xu, Yashpal S. Kanwar, Yachun Han
Diabetic Nephropathy (DN) is believed to be a major microvascular complication of diabetes. The hallmark of DN includes deposition of Extracellular Matrix (ECM) proteins, such as, collagen, laminin and fibronectin in the mesangium and renal tubulo-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4dab45fd28b57d158f9549b3e5b47c
https://europepmc.org/articles/PMC4863711/
https://europepmc.org/articles/PMC4863711/