Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tao, Xin"'
Publikováno v:
Chinese Journal of Polymer Science. 41:887-896
Autor:
Li Jian, Luo Wei, Kun-Lin Liu, Chao Gao, Huang Zhigang, Luoting Yu, Cui-Ting Peng, Chen Shuhui, Tao Xin, Charles Z. Ding
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:2511-2515
New analogues of antitubercular drug Delamanid were prepared, seeking drug candidates with enhanced aqueous solubility and high efficacy. The strategy involved replacement of phenoxy linker proximal to the 2-nitroimidazooxazole of Delamanid by piperi
Autor:
Klaus-Peter Knobeloch, Huib Ovaa, Daniel Jiménez Fernández, Paul P. Geurink, Bo-Tao Xin, Jin Gan
Publikováno v:
Organic and Biomolecular Chemistry, 17(48), 10148-10152
The linear synthesis of the N-terminal domain of mISG15 has been developed which enables the synthesis of full-length mISG15 and the activity-based probe Rho-mISG15-PA via native chemical ligation. Pilot experiments showed that the synthetic proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575f3111c5c0bd028e32ec0a4013b889
https://hdl.handle.net/1887/120725
https://hdl.handle.net/1887/120725
Autor:
Bogdan I. Florea, Bo-Tao Xin, Christofer Espinal, Gijsbert A. van der Marel, Herman S. Overkleeft, Dmitri V. Filippov, Gerjan de Bruin
Publikováno v:
ChemBioChem, 21(1-2), 248-255
Bioorthogonal chemistry allows the selective modification of biomolecules in complex biological samples. One application of this methodology is in two-step activity-based protein profiling (ABPP), a methodology that is particularly attractive where d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2582e65d4c86b84a5c18d3e612dd62c
https://hdl.handle.net/1887/3199007
https://hdl.handle.net/1887/3199007
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217630 (2019)
PLoS ONE
PLoS ONE
This paper explores how personality factors affect substance use disorders (SUDs) using explanatory item response modeling (EIRM). A total of 606 Chinese illicit drug users participated in our study. After removing the cases with missing values on th
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, 16(34), 6306-6315
Organic and Biomolecular Chemistry, 16(34), 6306-6315
The development of γ-thionorleucine (ThioNle) as a handle for native chemical ligation-desulfurization is reported here. ThioNle is a new addition to the expanding thiolated amino acid toolbox and serves as a methionine substitute in NCL with the ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ff2c3d36504165146a1a14fdbc069e
https://doi.org/10.1039/c8ob01627e
https://doi.org/10.1039/c8ob01627e
Autor:
Christoph Driessen, Herman S. Overkleeft, Bo-Tao Xin, Daniel Krappmann, Bogdan I. Florea, Yimeng Du, Gijsbert A. van der Marel, Gisela Schimmack
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:3312-3329
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Malt1) is a promising therapeutic target for the treatment of activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL). Several research groups have reported on the developmen
Autor:
Gijsbert A. van der Marel, Bo-Tao Xin, Gerjan de Bruin, Bogdan I. Florea, Herman S. Overkleeft, Jan-Willem Plomp
Publikováno v:
European Journal of Organic Chemistry. 2016:1132-1144
Human proteasomes are validated targets in oncology and are promising targets in immune related diseases. A number of peptide-based proteasome inhibitors have reached the clinic and several others are currently investigated in clinical trials. Despit
Publikováno v:
Chemical Communications. 52:6079-6082
The Rh(ii)-catalyzed sulfur ylide [1,2]-rearrangement of carbenoids generated from aryldiazoacetates has been realized via N-S bond insertion, generating tertiary sulfides in moderate to excellent yields. This demonstrates the first use of the sulfur
Autor:
Bogdan I. Florea, Kimberly M. Bonger, Selma Eising, Jurriaan J. A. Heming, Fleur Kleinpenning, Bo-Tao Xin, Herman S. Overkleeft
Publikováno v:
ChemBioChem, 19, 1648-1652
ChemBioChem, 19, 15, pp. 1648-1652
ChemBioChem, 19, 15, pp. 1648-1652
Bioorthogonal chemistry can be used for the selective modification of biomolecules without interfering with any other functionality that might be present. Recent developments in the field include orthogonal bioorthogonal reactions to modify multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e157f8cb2fb482ae1ded825ef594be
http://hdl.handle.net/2066/194248
http://hdl.handle.net/2066/194248