Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Wylie, J"'
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 263:G953-G959
We studied the propagation of phasic contractions initiated by tetraethylammonium (TEA, 1-10 mM), high K+ concentration (10-30 mM), and bethanechol (10(-6) to 10(-2) M) in a whole organ in vitro preparation of the opossum smooth muscle esophagus. TEA
Autor:
Ronald C. Arndorfer, Sushil K. Sarna, James F. Helm, Raymond G. Hoffmann, S. L. Bro, Wylie J. Dodds
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 261:G377-G383
We evaluated the control of phasic contractions in opossum esophageal circular smooth muscle by determining the contractile response in vitro to agents that cause membrane depolarization and excitation by different mechanisms. Transverse muscle strip
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 260:G258-G264
In this investigation we evaluated the effect of two new cholecystokinin (CCK) antagonists, CR 1409 and L364,718, on gallbladder emptying in the opossum. Gallbladder emptying was elicited by both exogenous and endogenous CCK. The three test challenge
Publikováno v:
Digestive Diseases and Sciences. 35:567-576
In this study, we evaluated the mechanism of action whereby cholecystokinin increases spike-burst rate of the opossum sphincter of Oddi (SO). Each spike burst corresponds to a peristaltic SO contraction. Two types of animal preparations were evaluate
Publikováno v:
The American journal of physiology. 259(5 Pt 1)
In conscious opossums, we evaluated the relationship between hepatic bile flow and the intestinal motor function during fasting as well as after feeding. In six opossums, bipolar electrodes were implanted from the gastric antrum to the terminal ileum
Autor:
Itsuo Takahashi, R.D. Layman, Wylie J. Dodds, William Y. Chey, Nobuyoshi Hanyu, Walter J. Hogan
Publikováno v:
Gastroenterology. 98(5 Pt 1)
The present study evaluated the mechanism of cholecystokinin-induced gallbladder contraction in awake opossums. Each of 19 chronic animal preparations had an indwelling gallbladder cannula for monitoring changes in gallbladder volume and a jugular ca
Autor:
Ronald C. Arndorfer, John H. Linehan, Walter J. Hogan, R A Komarowski, Wylie J. Dodds, James Toouli, R. Honda, Sushil K. Sarna
Publikováno v:
Journal of Clinical Investigation. 71:208-220
We studied the opossum sphincter of Oddi (SO) because in this species the SO is approximately 3 cm in length and its extraduodenal location permits recording of motor activity with negligible interference from duodenal motor activity. The SO segment
Autor:
Wylie J. Dodds, Richard J. Gilbert
Publikováno v:
Digestive Diseases and Sciences. 32:1130-1135
We assessed the characteristics of muscarinic neural transmission in the vagal inhibitory pathway to the lower esophageal sphincter (LES) of anesthetized opossums. LES relaxation was induced by electrical stimulation of the cervical vagus. Measuremen
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 249:G572-G579
We evaluated the control mechanism of peristaltic contractions in the opossum sphincter of Oddi (SO) by means of an in vitro preparation. At each of four sites spaced uniformly along the sphincter segment, a force transducer recorded contractions whi
Publikováno v:
Gastroenterology. 89:507-515
The lower esophageal sphincter (LES) exhibits cyclical phasic contractile activity synchronous with phases II and III of the gastric migrating motor complex. Motilin has been implicated in this process, although the exact mechanism is unknown. The ef