Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Tanner M"'
Autor:
Rowland H Han, Tanner M Johanns, Kaleigh F Roberts, Yu Tao, Jingqin Luo, Zezhong Ye, Peng Sun, Jacob Blum, Tsen-Hsuan Lin, Sheng-Kwei Song, Albert H Kim
Publikováno v:
Neuro-Oncology Advances. 5
Background Following chemoradiotherapy for high-grade glioma (HGG), it is often challenging to distinguish treatment changes from true tumor progression using conventional MRI. The diffusion basis spectrum imaging (DBSI) hindered fraction is associat
Autor:
Anthony Z. Wang, Hsiang Chih Lu, Zachary L. Skidmore, Obi L. Griffith, Gregory J. Zipfel, Katherine E. Miller, Megan Richters, Eric C. Leuthardt, Malachi Griffith, Albert H. Kim, Gavin P. Dunn, Tanner M. Johanns, Tammi L. Vickery, Joshua W. Osbun, Ralph G. Dacey, Bryan Fisk, Elaine R. Mardis, Michael R. Chicoine, Joshua L. Dowling, Maximilian Schaettler
Publikováno v:
Cancer Discov
Despite some success in secondary brain metastases, targeted or immune-based therapies have shown limited efficacy against primary brain malignancies such as glioblastoma (GBM). Although the intratumoral heterogeneity of GBM is implicated in treatmen
Autor:
NELSON OW SHAM, LEI ZHAO, ZIWEN ZHU, TANNER M. ROY, HUAPING XIAO, QIAN BAI, MARK R. WAKEFIELD, YUJIANG FANG
Publikováno v:
Anticancer research. 42(7)
From radiation therapy and surgery to chemotherapy and targeted therapy, the treatment of non-small cell lung cancer (NSCLC) has remarkably evolved over the past few decades. In recent years, immunotherapy has become an increasingly attractive area o
Autor:
Maximilian O Schaettler, Rupen Desai, Anthony Z Wang, Alexandra J Livingstone, Dale K Kobayashi, Andrew T Coxon, Jay A Bowman-Kirigin, Connor J Liu, Mao Li, Diane E Bender, Michael J White, David M Kranz, Tanner M Johanns, Gavin P Dunn
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e006121
BackgroundAdoptive cellular therapies with chimeric antigen receptor T cells have revolutionized the treatment of some malignancies but have shown limited efficacy in solid tumors such as glioblastoma and face a scarcity of safe therapeutic targets.
Autor:
Saad M Khan, Rupen Desai, Andrew Coxon, Alexandra Livingstone, Gavin P Dunn, Allegra Petti, Tanner M Johanns
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e005293
BackgroundGlioblastoma is a fatal disease despite aggressive multimodal therapy. PD-1 blockade, a therapy that reinvigorates hypofunctional exhausted CD8 T cells (Tex) in many malignancies, has not shown efficacy in glioblastoma. Loss of CD4 T cells
Autor:
Eric C. Leuthardt, Ashley Ghinaseddin, Albert H. Kim, Tanner M. Johanns, David Tran, Alice Zhou, Omar Butt, Jiayi Huang, Gavin P. Dunn, Jingxia Liu, Maryam Rahman, George Ansstas, Grayson Talcott, Jian Campian, Ruth Katumba, William Leidig, Milan G. Chheda
Publikováno v:
Neuro Oncol
BACKGROUND The blood brain barrier (BBB) remains a potential barrier to central nervous system (CNS) penetration of novel immunotherapies in recurrent glioblastoma (rGBM). Laser interstitial thermal therapy (LITT) was recently demonstrated to induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc1c453ff7b0ab8a48967d769c7930b
https://europepmc.org/articles/PMC8598780/
https://europepmc.org/articles/PMC8598780/
Autor:
Niranjan Y. Sardesai, Alfredo Perales-Puchalt, Tanner M. Johanns, Sarah Rochestie, Neil Cooch, Joann Peters, Gavin P. Dunn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundTumor neoantigens are epitopes derived from tumor-specific mutations. Such mutations can be incorporated in personalized vaccines to prime T cell responses against tumor specific antigens. DNA vaccines delivered with electroporation have re
Autor:
Joel R. Garbow, Tanner M. Johanns, Xia Ge, John A. Engelbach, Liya Yuan, Sonika Dahiya, Christina I. Tsien, Feng Gao, Keith M. Rich, Joseph J. H. Ackerman
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
PurposeClinical evidence suggests radiation induces changes in the brain microenvironment that affect subsequent response to treatment. This study investigates the effect of previous radiation, delivered six weeks prior to orthotopic tumor implantati
Autor:
Kyle C Molina, Matthew A Miller, Tanner M Johnson, Misha Huang, Amanda H Howard, Valida Bajrovic, Lorna Allen
Publikováno v:
Open Forum Infectious Diseases. 8
Background Bezlotoxumab significantly reduces the incidence of recurrent Clostridioides difficile infection (CDI); however, limited data are available in solid organ transplant (SOT) and hematopoietic cell transplant (HCT) recipients. Methods We cond
Publikováno v:
Melanoma Management
The introduction of immune checkpoint blockade (ICB) and BRAF-MEK inhibitors has substantially improved outcomes in patients with metastatic melanoma. However, several challenging factors may hinder the efficacy of ICB in patients with symptomatic in