Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sandrine Billet"'
Fatty Acid Signaling Impacts Prostate Cancer Lineage Plasticity in an Autocrine and Paracrine Manner
Autor:
Le Zhang, Sandrine Billet, Gabrielle Gonzales, Krizia Rohena-Rivera, Hayato Muranaka, Gina Chia-Yi Chu, Qian Yang, Hyung Kim, Neil A. Bhowmick, Bethany Smith
Publikováno v:
Cancers; Volume 14; Issue 14; Pages: 3449
Prostate cancer (PCa) affects an estimated 250,000 men every year and causes 34,000 deaths annually. A high-fat diet and obesity are associated with PCa progression and mortality. This study’s premise was the novel observation of crosstalk between
Autor:
Krizia Rohena Rivera, Sungyoung You, Minhyung Kim, Sandrine Billet, Johanna Hoeve-Scott, Gabrielle Gonzales, Chengqun Huang, Ashley Heard, Neil A. Bhowmick
Publikováno v:
Cancer Research. 82:3239-3239
Urinary bladder cancer accounts for 81,000 new cases per year and 4.7% of the new cancer diagnosis in the US. Even though most of the patients suffer from non-invasive lesions, around 70% will recur following surgical intervention. Chemotherapy with
Autor:
Ming Zhao, Y U Sun, Robert M. Hoffman, Maurizio Pellecchia, Hiromichi Oshiro, Sandrine Billet, Ahmed F. Salem, Luca Gambini, Neil A. Bhowmick
Publikováno v:
Cancers, Vol 12, Iss 2854, p 2854 (2020)
Cancers
Volume 12
Issue 10
Cancers, vol 12, iss 10
Cancers
Volume 12
Issue 10
Cancers, vol 12, iss 10
Simple Summary We demonstrate that pro-oncogenic EphA2 (ephrin type-A receptor 2) expression is activated in aggressive prostate cancers, and in mouse models of prostate cancers that are treated with enzalutamide. We also demonstrate in mouse models,
Autor:
Karen A. Cavassani, Sandrine Billet, Srinivas Nandana, Leland W.K. Chung, Neil A. Bhowmick, Edwin M. Posadas, Rajeev Mishra, Manisha Tripathi
Publikováno v:
Oncotarget
// Manisha Tripathi 1, * , Srinivas Nandana 1, * , Sandrine Billet 1 , Karen A. Cavassani 1 , Rajeev Mishra 1 , Leland W.K. Chung 1 , Edwin M. Posadas 1 and Neil A. Bhowmick 1, 2 1 Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, Cal
Autor:
Edwin M. Posadas, Maurizio Pellecchia, Luca Gambini, Sandrine Billet, Jie-Fu Chen, Si Wang, Ahmed F. Salem, Parima Udompholkul, Carlo Baggio, Neil A. Bhowmick
Publikováno v:
Cancer Research. 78:3913-3913
EphA2 is a tyrosine kinase receptor that is overexpressed in many cancer types like pancreatic, colon and breast cancers. Targeting cancer cells with an EphA2-targeting molecule conjugated with cytotoxic agents can spare normal cells from chemotherap
Autor:
Sayantan Mitra, Paul B. Fisher, Elena B. Pasquale, Si Wang, John L. Stebbins, Ana Fernandez, Shinichi Kitada, Swadesh K. Das, Sandrine Billet, Bainan Wu, Neil A. Bhowmick, Ziming Zhang, Roberta Noberini, Maurizio Pellecchia
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 19(1)
Purpose: YSA is an EphA2-targeting peptide that effectively delivers anticancer agents to prostate cancer tumors. Here, we report on how we increased the drug-like properties of this delivery system. Experimental Design: By introducing non-natural am
Autor:
Sandrine Billet, Leland W.K. Chung, Edwin M. Posadas, Manisha Tripathi, Srinivas Nandana, Neil A. Bhowmick
Publikováno v:
Cancer Research. 76:LB-274
Therapeutic targeting of the epithelial compartment alone in prostate cancer has resulted in unfavorable outcomes, including the development of resistance. Cabozantinib (XL184), a small molecule inhibitor of tyrosine kinases including c-MET and VEGFR