Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Pankaj Vats"'
Publikováno v:
South Asian Journal of Cancer.
Introduction Multiple modalities exist for treating keloids ranging from surgical, medical, chemotherapeutic, and radiation therapy. Different techniques of radiation therapy have been used to treat keloids as an adjuvant to surgical excision. With t
Publikováno v:
Cancer Research. 82:1900-1900
Introduction Next Generation Sequencing (NGS) played a crucial role in revolutionizing the field of human genetics to become an integral part of research and clinical management. Some examples are diagnosis and treatment of cancer patients, identifyi
Autor:
Kathryn McFadden, Arul M. Chinnaiyan, Andrew H. Zureick, Bailey Anderson, Sriram Venneti, Lili Zhao, Robert J. Lonigro, Karin M. Muraszko, Bernard L. Marini, Brendan Mullan, Patricia L. Robertson, Xuhong Cao, Pankaj Vats, Marcin Cieslik, Rajen Mody, Carl Koschmann, Jessica Everett, Paul E. McKeever, Sandra Camelo-Piragua, Yi-Mi Wu, Marcia Leonard, Hugh J. L. Garton, Cormac O. Maher, Andrew P. Lieberman, Katayoon Kasaian, Kevin Frank, John R. Prensner, Dan R. Robinson, Chandan Kumar-Sinha
Publikováno v:
JCO Precis Oncol
Purpose Brain tumors have become the leading cause of cancer-related mortality in young patients. Novel effective therapies on the basis of the unique biology of each tumor are urgently needed. The goal of this study was to evaluate the feasibility,
Autor:
David Smith, Moshe Talpaz, Megan E.V. Caram, Scott M. Schuetze, Mark M. Zalupski, Daniel F. Hayes, Erin F. Cobain, Chandan Kumar-Sinha, Robert J. Lonigro, Arul M. Chinnaiyan, Anne F. Schott, Erica Rabban, Elena M. Stoffel, Rashmi Chugh, Yi-Mi Wu, Vaibhav Sahai, Dan R. Robinson, Yu Ning, Michelle F. Jacobs, Ajjai Alva, Aaron M. Udager, Sandra Camelo-Piragua, Xuhong Cao, Pankaj Vats, Lakshmi P. Kunju, Francis P. Worden, Rui Wang, Marcin Cieslik, David R. Lucas, Janice Bell
Publikováno v:
JAMA Oncology
Key Points Question What is the clinical utility of genomic profiling for patients with advanced solid tumors? Findings In this cohort study of 1015 patients who underwent integrative genomic profiling, a high rate of pathogenic germline variants and
Autor:
Daniel L. Hertz, Erika Mora, Pankaj Vats, Bailey Anderson, Yi-Mi Wu, Rajen Mody, Kevin Frank, Andrew Glatz, Amy L. Pasternak, Dan R. Robinson, Robert J. Lonigro, Arul M. Chinnaiyan, Erica Rabban
Publikováno v:
JCO Precis Oncol
Purpose Evidence-based guidelines inform treatment decisions for patients for whom germline genetic information is available. Our real-time tumor sequencing program, which makes precision treatment decisions for patients with cancer, produces matched
Autor:
Pankaj Vats, Rajen Mody, Dan R. Robinson, Jonathan Bender, Bailey Anderson, Chandan Kumar-Sinha, Qing Li, Yi-Mi Wu, Marcin Cieslik, Gina Ney, Arul M. Chinnaiyan
Background Cancer remains the number one cause of disease-related mortality in children, and despite advances in the molecular understanding of leukemia and targeted therapies, refractory leukemia remains a leading cause of death. It therefore is ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0667ec3a054ed0e4cdd3a930c95a7a63
https://europepmc.org/articles/PMC7036640/
https://europepmc.org/articles/PMC7036640/
Autor:
Gavin Ha, Roman Gulati, Jonathan Reichel, Pankaj Vats, Andrew J. Armstrong, Colin C. Pritchard, Arul M. Chinnaiyan, Vaibhav G. Patel, Rana R. McKay, Anna C. H. Hoge, Ajjai Alva, William Oh, R. Bruce Montgomery, Deepak Kilari, Landon C. Brown, Michael T. Schweizer, Tanya B. Dorff
Publikováno v:
JCO Precis Oncol
PURPOSE Translational studies have shown that CDK12 mutations may delineate an immunoresponsive subgroup of prostate cancer, characterized by high neo-antigen burden. Given that these mutations may define a clinically distinct subgroup, we sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5753fd80165dc1328ffe28ce5f2d4a
https://europepmc.org/articles/PMC7363399/
https://europepmc.org/articles/PMC7363399/
Autor:
Pankaj Vats, Monika L. Burness, Arul M. Chinnaiyan, Erin F. Cobain, Robert J. Lonigro, Chandan Kumar-Sinha, Anne F. Schott, Aki Morikawa, Daniel F. Hayes, Robinson, Erica Rabban, C. Van Poznak, Max S. Wicha, Y-M Wu, Jeffrey B. Smerage, Jennifer J. Griggs
Publikováno v:
Cancer Research. 78:P2-09
Background: Immune checkpoint blockade (ICB) is effective in the treatment of various malignancies. Thus far, however, results in breast cancer have been mixed. Elevated tumor mutational load, and subsequent increased likelihood of forming immunogeni
Autor:
Ankit Sethia, Erin L. Crowgey, Todd E. Druley, Gary Burnett, Timothy Harkins, Karl Franke, Pankaj Vats
Publikováno v:
Cancer Research. 81:165-165
Introduction: The evolution of precision oncology will demand the integration of multi-omics, clinical data, demographics and outcomes, which is a complex and computationally intensive endeavor. Accurate and robust molecular characterization of pedia
Autor:
Pankaj Vats, Alyssa Paul, Yoshie Umemura, Timothy F. Cloughesy, Chase Thomas, Nicole Shonka, Daniel Martinez, Isabel Arrillaga-Romany, Ian Wolfe, Benjamin M. Ellingson, Arul M. Chinnaiyan, Evan Cantor, Zachary Miklja, John de Groot, Abed Rahman Kawakibi, Andrew S. Chi, Chandan Kumar-Sinha, Rebecca Harrison, Adam C. Resnick, Nicholas Butowski, Guangrong Lu, Minesh P. Mehta, Joshua E. Allen, Ashley Sumrall, Matthew Hall, Rajen Mody, Carl Koschmann, Mariella G. Filbin, Ruby Siada, Sylvia Kurz, Rohinton Tarapore, Sebastian M Waszak, Doured Daghistani, Hugh J. L. Garton, Viveka Nand Yadav, Javad Nazarian, Amy K. Bruzek, Patrick Y. Wen, Sabine Mueller, Tracy T. Batchelor, Sharon Gardner, Jessica R. Cummings, Sriram Venneti, Jonathan Schwartz, Brendan Mullan, Patricia L. Robertson, Li Jiang, Andrea Franson, Yazmin Odia, Rodrigo Cartaxo
Publikováno v:
Neuro Oncol
Patients with diffuse midline glioma (DMG) harboring H3 K27M mutation rarely survive longer than two years and have no proven therapies following first-line radiation. ONC201, a bitopic DRD2 antagonist and allosteric ClpP agonist, has shown encouragi