Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Louis M. Staudt"'
Autor:
Sebastian Scheich, Jiji Chen, Jiamin Liu, Frank Schnutgen, Julius C. Enssle, Michele Ceribelli, Craig J. Thomas, Jaewoo Choi, Vivian Morris, Tony Hsiao, Hang Nguyen, Boya Wang, Arnold Bolomsky, James D. Phelan, Sean Corcoran, Henning Urlaub, Ryan M. Young, Bjorn Haupl, George W. Wright, Da Wei Huang, Yanlong Ji, Xin Yu, Weihong Xu, Yandan Yang, Hong Zhao, Jagan Muppidi, Kuan-Ting Pan, Thomas Oellerich, Louis M. Staudt
Publikováno v:
Cancer Discovery.
Diffuse large B-cell lymphoma (DLBCL) can be subdivided into activated B-cell like (ABC) and germinal center B-cell-like (GCB) DLCBL. Self-antigen engagement of B-cell receptors (BCRs) in ABC tumors induces their clustering, thereby initiating chroni
Autor:
John Gerecitano, Jodi Carey, Christopher Major, Peter Johnson, Songbai Wang, Pier Luigi Zinzani, Wyndham H. Wilson, Steven Sun, Jessica Vermeulen, S. Martin Shreeve, Louis M. Staudt, Laurie H. Sehn, Michael Schaffer, Brendan P. Hodkinson, Sriram Balasubramanian
Publikováno v:
Br J Haematol
We assessed the concordance between immunohistochemistry (IHC) and gene expression profiling (GEP) for determining diffuse large B-cell lymphoma (DLBCL) cell of origin (COO) in the phase III PHOENIX trial of rituximab plus cyclophosphamide, doxorubic
Autor:
Oluwadamilola Olaku, Barbara A. Conley, S. Percy Ivy, Lisa M. McShane, Louis M. Staudt, Sophie M. King, Megan Sansevere, Benjamin Kim, Jeffrey D. White
Publikováno v:
Translational oncology. 25
The Exceptional Responders Initiative (ERI) at the National Cancer Institute attempts to correlate unusually good outcomes in patients with cancer with genetic targets in tumors and the therapies the patients received. It is not known if other factor
Autor:
Santiago Demajo, Anna Enjuanes, Robert Albero, German Ott, Eva Giné, Alba Navarro, Elaine S. Jaffe, David W. Scott, Elias Campo, Pedro Jares, Armando López-Guillermo, Guillem Clot, Ferran Nadeu, Giancarlo Castellano, Louis M. Staudt, Sílvia Beà, Andreas Rosenwald, Cristina Capdevila, Lisa M. Rimsza, Magda Pinyol
Publikováno v:
Clin Cancer Res
Purpose: Mantle cell lymphoma (MCL) is characterized by the t(11;14)(q13;q32) translocation leading to cyclin D1 overexpression. Cyclin D1 is a major cell-cycle regulator and also regulates transcription, but the impact of cyclin D1–mediated transc
Autor:
Brendan Hodkinson, Louis M. Staudt, George E. Wright, Martin Shreeve, Sriram Balasubramanian, Yue Fan, Wyndham H. Wilson, Da-Wei Huang, Jessica Vermeulen
Publikováno v:
Cancer cell. 39(12)
Summary In diffuse large B cell lymphoma (DLBCL), tumors belonging to the ABC but not GCB gene expression subgroup rely upon chronic active B cell receptor signaling for viability, a dependency that is targetable by ibrutinib. A phase III trial (“P
Autor:
Louis M. Staudt, Amy S. Kimball, Sven de Vos, Jerry Ping, Darrin M. Beaupre, Wyndham H. Wilson, Da-Wei Huang, Kevin A. Kwei, George E. Wright, Leslie Popplewell, Jutta K. Neuenburg, Saurabh Chhabra, Tycel Phillips
Publikováno v:
Leukemialymphoma. 62(9)
Relapsed/refractory diffuse large B-cell lymphoma (DLBCL) is difficult to cure; non-germinal center B-cell-like (non-GCB) and activated B-cell-like (ABC) DLBCL have worse outcomes than GCB DLBCL. Ibrutinib and lenalidomide are synergistic in vitro in
Autor:
Jeremy S. Abramson, Heiko Schöder, Wyndham H. Wilson, Richard I. Fisher, Nancy L. Bartlett, Matthew J. Maurer, Levi Pederson, John P. Leonard, Jane N. Winter, Nishitha Reddy, Louis M. Staudt, Nina D. Wagner-Johnston, Kristie A. Blum, Susan Mathew, Julie E. Chang, Ajay K. Gopal, Jonathan W. Friedberg, Brad S. Kahl, Amy Chadburn, Kristy L. Richards, Brandelyn N. Pitcher, Bruce D. Cheson, Mei Yin C. Polley, Andrew D. Zelenetz, Eric D. Hsi, Sin-Ho Jung
Publikováno v:
Journal of Clinical Oncology. 37:1790-1799
PURPOSE Alliance/CALGB 50303 (NCT00118209), an intergroup, phase III study, compared dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (DA-EPOCH-R) with standard rituximab, cyclophosphamide, doxorubicin, v
Autor:
Sirpa Leppä, Su-Peng Yeh, Ronit Gurion, Mehmet Turgut, Sriram Balasubramanian, Laurie H. Sehn, Anas Younes, Sen Hong Zhuang, Xiaonan Hong, Pier Luigi Zinzani, Andres Lopez-Hernandez, Shinya Rai, Caterina Patti, S. Martin Shreeve, Wojciech Jurczak, David Belada, Matthew C. Cheung, Olga Samoilova, Cheolwon Suh, Jessica Vermeulen, Louis M. Staudt, Jodi Carey, Catherine Thieblemont, Peter Johnson, C.S. Chiattone, Ulrich Dührsen, Grace Liu, Wyndham H. Wilson, Steven Sun, Jun Zhu
Publikováno v:
Journal of Clinical Oncology. 37:1285-1295
60th Annual Meeting of the American-Society-of-Hematology (ASH) -- DEC 01-04, 2018 -- San Diego, CA Jurczak, Wojciech/0000-0003-1879-8084; Johnson, Peter/0000-0003-2306-4974; ZINZANI, PIER LUIGI/0000-0002-2112-2651; Leppa, Sirpa/0000-0002-8265-511X W
Autor:
Louis M. Staudt, Roland Schmitz, Thomas Oellerich, Wyndham H. Wilson, George E. Wright, Ryan M. Young, James D. Phelan, Calvin A. Johnson, Arthur L. Shaffer, Da-Wei Huang
Publikováno v:
Annual Review of Cancer Biology. 3:429-455
Genomic analyses of diffuse large B cell lymphoma (DLBCL) are revealing the genetic and phenotypic heterogeneity of these aggressive lymphomas. In part, this heterogeneity reflects the existence of distinct genetic subtypes that acquire characteristi
Autor:
Christopher Major, Louis M. Staudt, P. Johnson, Brendan P. Hodkinson, Jessica Vermeulen, Jodi Carey, Michael Schaffer, M. Shreeve, Shean-Sheng Wang, Walter R. Wilson, Anas Younes, Steven Sun, Grace Liu, C. Loefgren, P. L. Zinzani, Laurie H. Sehn, Sen Hong Zhuang, Sriram Balasubramanian
Publikováno v:
Hematological Oncology. 37:140-142