Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Holger Nückel"'
Autor:
Peter A. Horn, Bettina Wagner, Vera Rebmann, Sabine Schramm, Alexander A. Celik, Ulrich Dührsen, Fabiola da Silva Nardi, Jan Dürig, Thomas Kraemer, Holger Nückel
Publikováno v:
Cancer. 123:814-823
BACKGROUND Human leukocyte antigen-E (HLA-E) is a nonclassical major histocompatibility complex class I molecule that recently came into sharper focus as a putative marker of advanced tumor stages and disease progression. In solid tumors, increased H
Autor:
Bernd Hertenstein, Lars Kurch, Roland Schroers, Andreas Hüttmann, Thomas Krohn, Georg Maschmeyer, Ariane Dienst, Heinz-Gert Höffkes, Ingo Brink, Gabriele Prange-Krex, Aruna Raghavachar, Alfred Klein, Christine Schmitz, Andreas Schwarzer, Gabriele Pöpperl, Wolfram Klapper, Andreas Hertel, Martin Griesshammer, Stefan P. Müller, Matthias Weckesser, Ralph Naumann, Heike Steiniger, Matthias Grube, Wolfgang Römer, Dieter Hoelzer, Marcus Brinkmann, Jan Dürig, Christiane Franzius, Thomas Südhoff, Frank M. Bengel, Holger Nückel, Claudia Ose, Ulrich Dührsen, Karl-Heinz Jöckel, Jan Rekowski, Thomas Höhler, Aristoteles Giagounidis, Arnold Ganser, Dennis Hahn, Paul La Rosée, Helga Bernhard, Jörg Kotzerke, Frank Kroschinsky, Hubertus Hautzel, Dirk Behringer, Jochen Schütte, Tobias Gaska, Rolf M. Mesters, Ferras Alashkar, Jens Holzinger, Stefan Wilop, Jörg Marienhagen, Martin Freesmeyer
Standard first-line treatment of aggressive B cell lymphoma comprises six or eight cycles of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) plus eight doses of rituximab (R). Whether adding two doses of rituximab to six cycles of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0a4c5c1983a3867477b6ca9f0e2df7
https://www.ncbi.nlm.nih.gov/pubmed/30610279
https://www.ncbi.nlm.nih.gov/pubmed/30610279
Autor:
Christiane Johr, Oleg Rubanov, Holger Nückel, Florian Nolte, Andrea Jarisch, Wolf-Karsten Hofmann, Stefan Albrecht, Burkhard Schmidt, Christiane Schumann, Thomas Geer, Holger Hebart
Publikováno v:
Journal of cancer research and clinical oncology. 144(8)
Iron overload (IOL) due to repetitive transfusions of packed red blood cells (pRBC) has a major impact on morbidity and mortality in patients with inherited bone marrow failure syndromes and hemoglobinopathies such as thalassemia and sickle cell dise
Autor:
René Scholtysik, Dirk de Beer, Ludger Sellmann, Alexander Röth, Gabriela M. Baerlocher, Ulrich Dührsen, Holger Nückel, Lewin Eisele, Ludger Klein-Hitpass, Jan Dürig
This study investigated the correlation of the extent of chromosomal aberrations including uniparental disomies (UPDs) by SNP-chip analysis and FISH to telomere length in 46 patients with CLL. CLL harboring high risk aberrations, i.e. deletions of 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ee9965ba9ee901a539797198ba83a4
https://www.ncbi.nlm.nih.gov/pubmed/26457386
https://www.ncbi.nlm.nih.gov/pubmed/26457386
Autor:
Holger Nückel, Yuan Zhu, Ulrich Sure, I. Erol Sandalcioglu, Nicolai El Hindy, Karl Worm, Hagen S. Bachmann, Nicole Lambertz, Michael Adamzik, Winfried Siffert
Publikováno v:
Journal of Neurosurgery. 114:1631-1639
Object Bcl-2 plays a key role in the downregulation of apoptosis and proliferation and leads to increased chemoresistance in glioblastoma multiforme (GBM). The authors investigated the role of a common regulatory single-nucleotide polymorphism (−93
Autor:
Peter A. Horn, Ralf Küppers, Vera Rebmann, Holger Nückel, Ludger Sellmann, Magdalena Switala, Hans Grosse-Wilde, Jan Dürig, Ulrich Dührsen
Publikováno v:
Leukemia. 24:1152-1159
Soluble or membrane-anchored ligands of NKG2D and their receptor have a critical role in the elimination of tumor cells and disease progression. Plasma samples of 98 patients with B-cell chronic lymphocytic leukemia (CLL) were analyzed with specific
Autor:
Holger Nückel, Crista H. Collins, Jan Dürig, Ulrich Dührsen, Winfried Siffert, Ulrich H. Frey, Ludger Sellmann
Publikováno v:
European Journal of Haematology. 83:541-549
Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. Therefore, we investigated FCRL2 mRNA expression in a large cohort with 152 CLL patients in order t
Autor:
Martin Heubner, Pauline Wimberger, Holger Nückel, Winfried Siffert, Friedrich Otterbach, Rainer Kimmig, Sabine Kasimir-Bauer
Publikováno v:
The International Journal of Biological Markers. 24:223-229
BackgroundBcl-2 plays a key role in the regulation of apoptosis. Recently, a novel regulatory single nucleotide polymorphism (–938C>A) in the inhibitory P2 BCL2 promoter was described. In this study we investigated its potential association with su
Autor:
J. Edelmann, R Deenen, Ludger Klein-Hitpass, Ludger Sellmann, Peter R. Ebeling, Jan Dürig, Andreas Hüttmann, Ulrich Dührsen, Anja Führer, Holger Nückel, Alexander Carpinteiro, Jürgen Thomale
Publikováno v:
Leukemia. 20:1774-1782
B-cell chronic lymphocytic leukaemia (B-CLL) is a heterogenous disease with a highly variable clinical course and analysis of zeta-associated protein 70 (ZAP-70) and CD38 expression on B-CLL cells allowed for identification of patients with good (ZAP
Autor:
Olaf Merkel, Hartmut Döhner, Šárka Pavlová, Šárka Pospíšilová, Mohd Arifin Kaderi, Peter Söderkvist, Richard Greil, Thorsten Zenz, Larry Mansouri, Axel Benner, Davide Rossi, Stephan Stilgenbauer, Ulrich Dührsen, Aneela Majid, Gareth L. Bond, David Oscier, Holger Nückel, Gianluca Gaidano, Mats Linderholm, Kerstin Willander, Martin J. S. Dyer, Richard Rosenquist, Anton Parker
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 11:S233-S235