Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bartonicek, A."'
Autor:
Louise A Baldwin, Nenad Bartonicek, Jessica Yang, Sunny Z Wu, Niantao Deng, Daniel Roden, Chia-Ling Chan, Ghamdan Al-Eryani, Damien J Zanker, Belinda S Parker, Alexander Swarbrick, Simon Junankar
Publikováno v:
Cancer Research. 82:P1-04
As cancers develop and spread they must continually evade immune destruction. Understanding mechanisms of immune evasion in cancer is clinically significant as demonstrated with the successes of immune checkpoint inhibitors. Breast cancer is known to
Autor:
Anja Rockstroh, John D. Wade, Colleen C. Nelson, Martin C. Sadowski, Laszlo Otvos, Nenad Bartonicek, Melanie Lehman, Lisa Philp
Publikováno v:
Endocrine-Related Cancer. 27:711-729
Adiponectin is an adipokine originally identified as dysregulated in obesity, with a key role in insulin sensitisation and in maintaining systemic energy balance. However, adiponectin is progressively emerging as having aberrant signalling in multipl
Autor:
Mark P. Molloy, Andrew M. K. Law, Alexander Swarbrick, David Gallego-Ortega, Nenad Bartonicek, Maria Kalyuga, Jason S. Carroll, Christopher J. Ormandy, Daniel L. Roden, Susan J. Clark, Warren Kaplan, Catherine L. Piggin, Christoph Krisp, Samantha R. Oakes, Matthew J. Naylor
Publikováno v:
PLoS Genetics, Vol 16, Iss 1, p e1008531 (2020)
PLoS Genetics
PLoS Genetics
Acquired resistance to endocrine therapy is responsible for half of the therapeutic failures in the treatment of breast cancer. Recent findings have implicated increased expression of the ETS transcription factor ELF5 as a potential modulator of estr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ea307d580ac9973a2abd0783ca1165
https://www.repository.cam.ac.uk/handle/1810/302145
https://www.repository.cam.ac.uk/handle/1810/302145
Autor:
Charles L. Bidgood, Michelle S. Libério, Martin C. Sadowski, Melanie Lehman, Colleen C. Nelson, John D. Wade, Jennifer H. Gunter, Lisa Philp, Anja Rockstroh, Stephen McPherson, Laszlo Otvos, Gregor Tevz, Nenad Bartonicek, Atefeh Taherian Fard
Publikováno v:
Philp, Lisa K; Rockstroh, Anja; Sadowski, Martin C; Taherian Fard, Atefeh; Lehman, Melanie; Tevz, Gregor; Libério, Michelle S; Bidgood, Charles L; Gunter, Jennifer H; McPherson, Stephen; Bartonicek, Nenad; Wade, John D; Otvos, Laszlo; Nelson, Colleen C (2021). Leptin antagonism inhibits prostate cancer xenograft growth and progression. Endocrine-related cancer, 28(5), pp. 353-375. BioScientifica Ltd. 10.1530/ERC-20-0405
Hyperleptinaemia is a well-established therapeutic side effect of drugs inhibiting the androgen axis in prostate cancer (PCa), including main stay androgen deprivation therapy (ADT) and androgen targeted therapies (ATT). Given significant crossover b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ea4121f76d184e85e5e2e7dda6b1d9
https://boris.unibe.ch/161800/1/33794502.pdf
https://boris.unibe.ch/161800/1/33794502.pdf
Autor:
Stephen McPherson, Marcel E. Dinger, Chenwei Wang, Martin C. Sadowski, Kaylyn D. Tousignant, Anja Rockstroh, Atefeh Taherian Fard, Lisa Philp, Nenad Bartonicek, Colleen C. Nelson, Melanie Lehman
Publikováno v:
Molecular Cancer Research. 17:1166-1179
De novo lipogenesis is a well-described androgen receptor (AR)–regulated metabolic pathway that supports prostate cancer tumor growth by providing fuel, membrane material, and steroid hormone precursor. In contrast, our current understanding of lip
Autor:
Kate Harvey, Oliver Braubach, Ghamdan Al-Eryani, Camelia Quek, Jonathan R. Stretch, Aaron Mayer, Chi Buckley, Kerwin F. Shannon, Ines Pires da Silva, Richard A. Scolyer, Alexander M. Menzies, Nenad Bartonicek, Robyn P. M. Saw, James S. Wilmott, Georgina V. Long, John F. Thompson, Alexander Swarbrick
Publikováno v:
Cancer Research. 81:2761-2761
Primary and acquired resistance to anti-PD-1 and CTLA-4 immunotherapies remains a major obstacle to improving the outcomes of cancer patients. This study utilized a combination of scRNAseq, CITE-seq, a method for CODEX, 40+ protein marker tissue imag
Publikováno v:
Molecular Cancer
The previous decade has seen long non-coding RNAs (lncRNAs) rise from obscurity to being defined as a category of genetic elements, leaving its mark on the field of cancer biology. With the current number of curated lncRNAs increasing by 10,000 in th
Autor:
Andrew E. Tee, Pei Y. Liu, Giorgio Milazzo, Kate M. Hannan, Jesper Maag, Nenad Bartonicek, Renhua Song, Chen C. Jiang, Xu D. Zhang, Murray D. Norris, Michelle Haber, Glenn M. Marshall, Jinyan Li, Jo Vandesompele, John S. Mattick, Pieter Mestdagh, Giovanni Perini, Ross D. Hannan, Marcel E. Dinger, Tao Liu
Publikováno v:
Cancer Research. 78:2453-2453
N-Myc gene amplification occurs in one quarter of human neuroblastoma tissues, and is a marker for poor patient prognosis. We performed RNA sequencing experiments, and identified 5 transcripts, including RP1NB1, which were most considerably different
Autor:
John S. Mattick, Marcel E. Dinger, Michelle Haber, Ross D. Hannan, Pieter Mestdagh, Andrew E. Tee, Giorgio Milazzo, Renhua Song, Giovanni Perini, Murray D. Norris, Pei Y. Liu, Katherine M. Hannan, Chen C. Jiang, Nenad Bartonicek, Jo Vandesompele, Jinyan Li, Glenn M. Marshall, Tao Liu, Jesper L.V. Maag, Xu D. Zhang
Publikováno v:
Cancer Research. 76:2664-2664
N-Myc gene amplification occurs in one quarter of human neuroblastoma tissues, and is a marker for poor patient prognosis. We performed RNA sequencing experiments, and identified 5 transcripts, including RP1NB1, which were most considerably different