Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Abu Syed Md Anisuzzaman"'
Publikováno v:
Cancer Research. 83:5089-5089
Induction of apoptosis is a critical mechanism underlying the durable efficacy of cancer treatment agents. Bax is a major proapoptotic protein whose activation is required for apoptotic cell death. We have recently discovered that small molecule Bax
Autor:
Dongsheng Wang, Zhengjia Chen, Dong M. Shin, Chao Zhang, A.R.M. Ruhul Amin, Zhuo Georgia Chen, Mohammad Aminur Rahman, Abedul Haque, Abu Syed Md Anisuzzaman
Publikováno v:
Molecular Cancer Therapeutics. 16:729-738
We previously reported that the EGFR-targeted inhibitor erlotinib induces G1 arrest of squamous cell carcinoma of the head and neck (SCCHN) cell lines without inducing significant apoptosis. Large-scale genomic studies suggest that >50% of SCCHN case
Autor:
Dong M. Shin, Abu Syed Md Anisuzzaman, Abedul Haque, Zhuo Georgia Chen, Zhengjia Chen, Chao Zhang, Mohammad Aminur Rahman, A.R.M. Ruhul Amin, Dongsheng Wang
Publikováno v:
Molecular Cancer Therapeutics. 19:1955-1955
Publikováno v:
Cancer Research. 80:1907-1907
Purpose: Molecularly targeted agents will play a major role in the next generation of personalized cancer therapies. However, intrinsic and acquired resistance to targeted agents poses challenges to the success of such treatments. The purpose of the
Autor:
Dong M. Shin, Zhuo Georgia Chen, Abu Syed Md Anisuzzaman, Yuan Liu, Gabriel Sica, Abedul Haque, Dongsheng Wang, Selwyn J. Hurwitz, Mohammad Aminur Rahman, James R. Fuchs, Fadlo R. Khuri, A.R.M. Ruhul Amin
Publikováno v:
Cancer prevention research (Philadelphia, Pa.). 9(1)
Despite its high promise for cancer prevention and therapy, the potential utility of curcumin in cancer is compromised by its low bioavailability and weak potency. The purpose of the current study was to assess the in vitro and in vivo efficacy and p
Publikováno v:
Cancer Research. 77:4097-4097
Purpose: Molecularly targeted agents will play a major role in the next generation of personalized cancer therapies. However, intrinsic and acquired resistance to targeted agents poses challenges to the success of such treatments. The purpose of the
Publikováno v:
Cancer Research. 76:3502-3502
Purpose: Molecularly targeted agents will play a major role in the next generation of personalized cancer therapies. The EGFR-targeted monoclonal antibody cetuximab is currently the only FDA-approved targeted treatment for head and neck cancers (HNC)