Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Angelo M. De Marzo"'
Autor:
Lorelei A. Mucci, Alan K. Meeker, Edward Giovannucci, Meir J. Stampfer, Reza Zarinshenas, Angelo M. De Marzo, Elizabeth A. Platz, Misop Han, Tamara L. Lotan, Christine Davis, Corinne E. Joshu, Jiayun Lu, John R. Barber, Christopher M. Heaphy
Publikováno v:
The journal of pathology. Clinical research. 8(5)
PurposeCurrent biomarkers are inadequate prognostic predictors in localized prostate cancer making treatment decision-making challenging. Previously, we observed that the combination of more variable telomere length among prostate cancer cells and sh
Autor:
Tamara L. Lotan, John R. Barber, Edward M. Schaeffer, Laneisha Maldonado, Angelo M. De Marzo, Corinne E. Joshu, Liana B. Guedes, Mario A. Eisenberger, Jiayun Lu, Harsimar B. Kaur, Scott A. Tomlins, Karen S. Sfanos, Logan Reitz
Publikováno v:
Hum Pathol
Summary The makeup of the tumor immune microenvironment may be associated with tumor somatic genomic alterations and plays a key role in tumor progression and response to immunotherapy. We examined the association of tumor-infiltrating T-cell density
Autor:
Alan K. Meeker, William G. Nelson, Charles G. Drake, Srinivasan Yegnasubramanian, George J. Netto, David M. Esopi, Liana B. Guedes, Jun Luo, Kunhwa Kim, Michael C. Haffner, Tamara L. Lotan, Angelo M. De Marzo, Harrison Tsai, Gunes Guner, Doreen N. Palsgrove, Diana Taheri, Rajni Sharma, Arul M. Chinnaiyan, Rohit Mehra, Qizhi Zheng, Emmanuel S. Antonarakis
Publikováno v:
The American Journal of Pathology. 188:1478-1485
Antibodies targeting the programmed cell death protein 1/programmed death-ligand 1 (PD-L1) interaction have shown clinical activity in multiple cancer types. PD-L1 protein expression is a clinically validated predictive biomarker of response for such
Publikováno v:
International journal of experimental pathology. 98(4)
Identification of genes specifically deregulated in prostate adenocarcinoma may lead to discovery of new oncogenes/tumour suppressors with clinical relevance for diagnosis, prognosis and/or therapy. CXXC5 is a gene encoding a retinoid-inducible nucle
Autor:
Jessica L. Hicks, Alcides Chaux, George J. Netto, Siobhan Sutcliffe, Antoun Toubaji, Angelo M. De Marzo, Kristen Lecksell, Elizabeth A. Platz
Publikováno v:
Human Pathology. 43:1852-1865
Prostate cancer remains a major health problem in the United States. Established clinicopathologic parameters such as Gleason score, T stage, and prostate-specific antigen levels are currently the guiding tools for prognostication and disease managem
Autor:
Angelo M. De Marzo, Russell Vang, Robert B. Jenkins, Fusheng Lan, Stephanie R. Fink, Ashley Cimino-Mathews, Saraswati Sukumar, Hind Nassar, Pedram Argani, Aatur D. Singhi, Jessica Hicks, John H. Fetting
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
In breast cancer, amplification of MYC is consistently observed in aggressive forms of disease and correlates with poor prognosis and distant metastases. However, to date, a systematic analysis of MYC amplification in metastatic breast cancers has no
Autor:
Karen S. Sfanos, Angelo M. De Marzo
Publikováno v:
Histopathology. 60:199-215
Chronic inflammation is now known to contribute to several forms of human cancer, with an estimated 20% of adult cancers attributable to chronic inflammatory conditions caused by infectious agents, chronic non-infectious inflammatory diseases and/or
Autor:
Srinivasan Yegnasubramanian, Tsuyoshi Iwata, William G. Nelson, Cheryl M. Koh, Angelo M. De Marzo, Bora Gurel
Publikováno v:
Advances in Anatomic Pathology. 15:319-331
Prostatic adenocarcinoma is extremely common in Western nations, representing the second leading cause of cancer death in American men. The recent application of increasingly sophisticated molecular approaches to the study of prostate cancer in this
Autor:
Angelo M. De Marzo, Mark A. Rubin
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 17(3)
Multiple factors contribute to the high incidence and prevalence of prostate cancer including race, ethnicity, diet, environment, widespread awareness through prostate-specific antigen screening and genetics. Linkage analysis has identified several c