Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Peiwei Chai"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-10 (2020)
Abstract Extrachromosomal DNA (ecDNA), gene-encoding extrachromosomal particles of DNA, is often present in tumor cells. Recent studies have revealed that oncogene amplification via ecDNA is widespread across a diverse range of cancers. ecDNA is invo
Externí odkaz:
https://doaj.org/article/e43dde009831401abded526b190b7b54
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-10 (2020)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Extrachromosomal DNA (ecDNA), gene-encoding extrachromosomal particles of DNA, is often present in tumor cells. Recent studies have revealed that oncogene amplification via ecDNA is widespread across a diverse range of cancers. ecDNA is involved in i
Autor:
Xuyang Wen, Jiayan Fan, Renbing Jia, Huixue Wang, Shengfang Ge, Peiwei Chai, He Zhang, Xiaoyu Zhang, Xianqun Fan, Tianyi Ding
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss, Pp 317-325 (2020)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Although CCCTC binding factor (CTCF) has been demonstrated to play a variety of often contradictory roles in tumorigenesis, little is known about its function in the tumorigenesis of ocular melanoma. Here, we generated two artificial CTCF peptides (D
Publikováno v:
OncoTargets and Therapy. 12:4297-4308
Background: SKP2 is considered an oncogene involved in various malignancies. SKP2 protein is a critical subunit of the SKP1-CUL1-F-box (SCF) E3 ligase complex which affects the cell cycle profoundly by specifically recognizing cell cycle regulators a
Autor:
Shengfang Ge, Chuandi Zhou, Xianqun Fan, Renbing Jia, Peiwei Chai, Fang Li, Yongyun Li, Leilei Zhang, Yingxiu Luo, Xiaoyu He, He Zhang, Xiaoling Yuan, Jie Yang
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-20 (2020)
Molecular Cancer
Molecular Cancer
BackgroundLong non-coding RNAs (lncRNAs) have been identified as important epigenetic regulators that play critical roles in human cancers. However, the regulatory functions of lncRNAs in tumorigenesis remains to be elucidated. Here, we aimed to inve
Autor:
Shengfang Ge, Renbing Jia, Peiwei Chai, Hui Pan, He Zhang, Hongyan Ni, Ruobing Jia, Xianqun Fan, Yingyun Shi, Huixue Wang, Shaoyun Wang, Chuandi Zhou
Publikováno v:
Nucleic Acids Research
Aberrant chromatin transformation dysregulates gene expression and may be an important driver of tumorigenesis. However, the functional role of chromosomal dynamics in tumorigenesis remains to be elucidated. Here, using in vitro and in vivo experimen