Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jeremie Boucher"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The prevalence of obesity and metabolic diseases continues to rise, which has led to an increased interest in studying adipose tissue to elucidate underlying disease mechanisms. The use of genetic mouse models has been critical for understanding the
Externí odkaz:
https://doaj.org/article/1d7dd6c245794c8e9ef4310dbcdad811
Autor:
Ida Alexandersson, Nahida Arifen, Firoozeh Salehzadeh, Anders Thorell, Carolina E. Hagberg, Jeremie Boucher, Kirsty L. Spalding, Qian Li, Ping Chen, Niels Krämer, Matthew J. Harms, Carole Knibbe, Shuai Lang, Helena Silva Cascales, Eleni Terezaki, Mervi T. Hyvönen, Myriam Aouadi, Maria Kutschke
Publikováno v:
Nature Medicine
Nature Medicine, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
Nature Medicine, Nature Publishing Group, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
Nature Medicine, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
Nature Medicine, Nature Publishing Group, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
International audience; Obesity is considered an important factor for many chronic diseases, including diabetes, cardiovascular disease and cancer. The expansion of adipose tissue in obesity is due to an increase in both adipocyte progenitor differen
Autor:
Tobias Kroon, Therese Hagstedt, Ida Alexandersson, Annett Ferm, Marie Petersson, Stefanie Maurer, Bader Zarrouki, Kristina Wallenius, Nicholas D. Oakes, Jeremie Boucher
Publikováno v:
Science Translational Medicine. 14
Circadian rhythms play a critical role in regulating metabolism, including daily cycles of feeding/fasting. Glucokinase (GCK) is central for whole-body glucose homeostasis and oscillates according to a circadian clock. GCK activators (GKAs) effective
Autor:
Miguel A. Lanaspa, C. Ronald Kahn, Samir Softic, Senad Divanovic, Richard J. Johnson, Kimber L. Stanhope, Jeremie Boucher
Publikováno v:
Crit Rev Clin Lab Sci
Excessive caloric intake in a form of high-fat diet (HFD) was long thought to be the major risk factor for development of obesity and its complications, such as fatty liver disease and insulin resistance. Recently, there has been a paradigm shift and
Autor:
Vilborg Palsdottir, Ann Hammarstedt, Thomas U. Greiner, Ivet Elias, Stefanie Maurer, Tobias Kroon, Fatima Bosch, Shahram Hedjazifar, John R. Grünberg, Jenny M. Hoffmann, Jeremie Boucher, Ulf Smith
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 32, Iss, Pp 15-26 (2020)
Molecular Metabolism, Vol 32, Iss, Pp 15-26 (2020)
Objective Bone morphogenetic protein 4 (BMP4) adeno-associated viral vectors of serotype 8 (AAV8) gene therapy targeting the liver prevents the development of obesity in initially lean mice by browning the large subcutaneous white adipose tissue (WAT
Publikováno v:
Nature Reviews Endocrinology
Nature Reviews Endocrinology, 2021, 17 (5), pp.276-295. ⟨10.1038/s41574-021-00471-8⟩
Nature Reviews Endocrinology, Nature Publishing Group, 2021, 17 (5), pp.276-295. ⟨10.1038/s41574-021-00471-8⟩
Nat. Rev. Endocrinol. 17, 276-295 (2021)
Nature reviews endocrinology
Nature Reviews Endocrinology, 2021, 17 (5), pp.276-295. ⟨10.1038/s41574-021-00471-8⟩
Nature Reviews Endocrinology, Nature Publishing Group, 2021, 17 (5), pp.276-295. ⟨10.1038/s41574-021-00471-8⟩
Nat. Rev. Endocrinol. 17, 276-295 (2021)
Nature reviews endocrinology
International audience; In mammals, the white adipocyte is a cell type that is specialized for storage of energy (in the form of triacylglycerols) and for energy mobilization (as fatty acids). White adipocyte metabolism confers an essential role to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9562174f8437731a6036433fd1767e
https://ut3-toulouseinp.hal.science/hal-03320059
https://ut3-toulouseinp.hal.science/hal-03320059
Autor:
Jenny M. Hoffmann, Ivet Elias, Roxana Khatib Shahidi, Jeremie Boucher, Ann Hammarstedt, Christopher Church, Shahram Hedjazifar, Fatima Bosch, Laurianne Bonnet, Ritesh K. Baboota, Ulf Smith, Stephanie Heasman
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247300 (2021)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
PLoS ONE
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
PLoS ONE
Objective Gremlin 1 (GREM1) is a secreted BMP2/4 inhibitor which regulates commitment and differentiation of human adipose precursor cells and prevents the browning effect of BMP4. GREM1 is an insulin antagonist and serum levels are high in type 2 di
Autor:
Qian, Li, Carolina E, Hagberg, Helena, Silva Cascales, Shuai, Lang, Mervi T, Hyvönen, Firoozeh, Salehzadeh, Ping, Chen, Ida, Alexandersson, Eleni, Terezaki, Matthew J, Harms, Maria, Kutschke, Nahida, Arifen, Niels, Krämer, Myriam, Aouadi, Carole, Knibbe, Jeremie, Boucher, Anders, Thorell, Kirsty L, Spalding
Publikováno v:
Nature medicine. 27(11)
Obesity is considered an important factor for many chronic diseases, including diabetes, cardiovascular disease and cancer. The expansion of adipose tissue in obesity is due to an increase in both adipocyte progenitor differentiation and mature adipo
Autor:
Bader, Zarrouki, Jeremie, Boucher
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2164
Nonalcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease (NAFLD), characterized by steatosis (fat within the liver), inflammation, and fibrosis, which may progress to cirrhosis and hepatocellular carcinoma. Despite the
Publikováno v:
The FEBS journalReferences. 288(12)
Brown and brite adipocytes contribute to energy expenditure through nonshivering thermogenesis. Though these cell types are thought to arise primarily from the de novo differentiation of precursor cells, their abundance is also controlled through the