Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrea Dlasková"'
Autor:
Petr Ježek, Lukáš Alán, Nikola Capková, Hana Engstová, Vojtěch Pavluch, Frantisek Saudek, Tomáš Špaček, Andrea Dlasková, Zuzana Berková
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports
Scientific Reports
Hypertrophic pancreatic islets (PI) of Goto Kakizaki (GK) diabetic rats contain a lower number of β-cells vs. non-diabetic Wistar rat PI. Remaining β-cells contain reduced mitochondrial (mt) DNA per nucleus (copy number), probably due to declining
Autor:
Andrea Dlasková, Petr Ježek
Publikováno v:
Mitochondrion. 49
Type 2 diabetes progression stems from dysfunction of β-cells, besides the peripheral insulin resistance. Mitochondria as glucose sensor and regulation center are impaired at various stages of this progression. Their biogenesis and functional impair
Autor:
Katarína Smolková, Andrea Dlasková, Jitka Špačková, Anežka Kahancová, Hana Engstová, Martin Bartoš, Petr Ježek, Vojtěch Pavluch, Tomáš Špaček, Lydie Hlavatá
Publikováno v:
Biochimica et biophysica acta. Bioenergetics. 1859(9)
3D super-resolution microscopy based on the direct stochastic optical reconstruction microscopy (dSTORM) with primary Alexa-Fluor-647-conjugated antibodies is a powerful method for accessing changes of objects that could be normally resolved only by
Autor:
Lydie Hlavatá, Hana Engstová, Petr Ježek, David Pajuelo Reguera, Martin Jabůrek, Mark D. Lessard, Lukáš Alán, Andrea Dlasková
Publikováno v:
Journal of Bioenergetics and Biomembranes. 47:255-263
Mitochondrial nucleoids are confined sites of mitochondrial DNA existing in complex clusters with the DNA–compacting mitochondrial (mt) transcription factor A (TFAM) and other accessory proteins and gene expression machinery proteins, such as a mt
Autor:
Katarína Smolková, Martin Jabůrek, Jitka Šantorová, Lukáš Alán, Lydie Plecitá-Hlavatá, Andrea Dlasková, Jan Tauber, Tomáš Špaček, Petr Ježek
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 45:593-603
Mitochondrial DNA (mtDNA) is organized in nucleoids in complex with accessory proteins, proteins of mtDNA replication and gene expression machinery. A robust mtDNA genome is represented by hundreds to thousands of nucleoids in cell mitochondrion. Det
Publikováno v:
Molecular medicine reports. 12(4)
Oligomer aggregation of green-to-red photoconvertible fluorescent protein Eos (EosFP) is a natural feature of the wild‑type variant. The aim of the present study was to follow up mitochondrial nucleoid behavior under natural conditions of living ce
Autor:
Lukáš Alán, Martin Jabůrek, Petr Ježek, Tomas Olejar, Tomáš Špaček, Andrea Dlasková, Hana Engstová
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1837:e24
Publikováno v:
Free Radical Biology and Medicine. 53:S19
Publikováno v:
Free Radical Biology and Medicine. 49:S94
Autor:
Jaroslav Zelenka, Jan Tauber, Lukáš Alán, Zdenek Svindrych, Tomáš Špaček, Joerg Bewersdorf, Petr Jezek, Andrea Dlasková, Katarína Smolková, Jitka Šantorová
Publikováno v:
ResearcherID
Mitochondrial (mt) network undergoes locally frequent fragmentation and fusion events. When integrated over time, its basic morphology encompasses highly interconnected mt reticulum, a single mitochondrion within the cell (1). Upon certain insults an
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