Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jorge Cruz-Reyes"'
Autor:
James A. Wohlschlegel, Gokulan Kuppan, Sing-Hoi Sze, Yu-He Liang, Xinhua Ji, Bhaskara R. Madina, Laurie K. Read, Kurtis M. Downey, Ajay A. Vashisht, James C. Sacchettini, Jorge Cruz-Reyes
Publikováno v:
RNA. 17:1821-1830
The mitochondrial genome of kinetoplastids, including species of Trypanosoma and Leishmania, is an unprecedented DNA structure of catenated maxicircles and minicircles. Maxicircles represent the typical mitochondrial genome encoding components of the
Publikováno v:
Molecular and Cellular Biology. 21:884-892
Trypanosome RNA editing is a massive processing of mRNA by U deletion and U insertion, directed by trans-acting guide RNAs (gRNAs). A U deletion cycle and a U insertion cycle have been reproduced in vitro using synthetic ATPase (A6) pre-mRNA and gRNA
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 8, p e12235 (2010)
PLoS ONE, Vol 5, Iss 8, p e12235 (2010)
Mitochondrial mRNA editing in Trypanosoma brucei requires the specific interaction of a guide RNA with its cognate mRNA. Hundreds of gRNAs are involved in the editing process, each needing to target their specific editing domain within the target mes
Autor:
Kari Halbig, Jorge Cruz-Reyes, Lawrence J. Dangott, Catherine Cifuentes-Rojas, Mónica De Nova-Ocampo, Anastasia Sacharidou, Alfredo J. Hernandez
Trypanosome U insertion and U deletion RNA editing of mitochondrial pre-mRNAs is catalyzed by multisubunit editing complexes as directed by partially complementary guide RNAs. The basic enzymatic activities and protein composition of these high-molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5423b8892d71fda30a4eb07ec3c13418
https://europepmc.org/articles/PMC1484423/
https://europepmc.org/articles/PMC1484423/
Publikováno v:
International journal for parasitology. 36(12)
Mitochondrial gene expression in kinetoplastids is controlled after transcription, potentially at the levels of RNA maturation, stability and translation. Among these processes, RNA editing by U-insertion/deletion catalysed by multi-subunit editing c
Publikováno v:
Scopus-Elsevier
RNA editing in kinetoplastids, the specific insertion and deletion of U residues, requires endonuclease cleavage of the pre-mRNA at each cycle of insertion/deletion. We have resolved three endoribonuclease activities from Trypanosoma brucei mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0a3a80a75baea5c80e164c594bbf74c7
https://europepmc.org/articles/PMC1369480/
https://europepmc.org/articles/PMC1369480/