Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Akiyuki Fujii"'
Publikováno v:
Journal of Health Science. 57:414-419
Strain differences in the induction of cytochrome P450 (CYP) affect drug actions and side effects. Strain differences in the induction of CYP are important to evaluate drug-drug interactions in CYPs. We clarified strain differences in the induction o
Autor:
Atsushi Kawase, Hiroshi Komura, Masahiro Iwaki, Makiko Negoro, Miki Ishikubo, Ryosuke Akai, Akiyuki Fujii
Publikováno v:
Drug metabolism and pharmacokinetics. 23(3)
This study aimed to clarify the differences in mRNA levels of cytochrome P450 (CYP) isoforms and nuclear receptors between Dark Agouti (DA) and Sprague-Dawley (SD) rats which are animal models for poor metabolizers and extensive metabolizers for CYP2