Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
Cynthia A. Moylan, Alisha M. Mavis, Dereje Jima, Rachel Maguire, Mustafa Bashir, Jeongeun Hyun, Melanie N. Cabezas, Alice Parish, Donna Niedzwiecki, Anna Mae Diehl, Susan K. Murphy, Manal F. Abdelmalek, Cathrine Hoyo
Publikováno v:
Epigenetics, Vol 17, Iss 11, Pp 1446-1461 (2022)
Non-Alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in children. Epigenetic alterations, such as through DNA methylation (DNAm), may link adverse childhood exposures and fatty liver and provide non-invasive methods
Externí odkaz:
https://doaj.org/article/340dddde15ac419da0f5f9f960cb993c
Autor:
Arun J. Sanyal, Stephen A. Williams, Joel E. Lavine, Brent A. Neuschwander-Tetri, Leigh Alexander, Rachel Ostroff, Hannah Biegel, Kris V. Kowdley, Naga Chalasani, Srinivasan Dasarathy, Anna Mae Diehl, Rohit Loomba, Bilal Hameed, Cynthia Behling, David E. Kleiner, Saul J. Karpen, Jessica Williams, Yi Jia, Katherine P. Yates, James Tonascia
Publikováno v:
Journal of hepatology, vol 78, iss 4
J Hepatol
J Hepatol
There is an unmet need for development of non-invasive tests for the diagnostic assessment and monitoring of nonalcoholic fatty liver disease (NAFLD).Using modified-aptamer proteomics, we assayed 5220 proteins in each of 2852 single serum samples fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98d930021ee18e344ed6b8fc32118b5
https://escholarship.org/uc/item/0d9809np
https://escholarship.org/uc/item/0d9809np
Autor:
Manal F. Abdelmalek, Jeongeun Hyun, Steven R. Patierno, Rebecca Caffrey, Cynthia A. Moylan, Muthana Al Abo, Anna Mae Diehl, Xiyou Zhou, Seh-Hoon Oh, Arun J. Sanyal, Kun Xiang, Rajesh Kumar Dutta, Raquel Maeso-Díaz, Jennifer A. Freedman
Publikováno v:
J Hepatol
Background & Aims Non-alcoholic fatty liver disease (NAFLD), the hepatic correlate of the metabolic syndrome, is a major risk factor for hepatobiliary cancer (HBC). Although chronic inflammation is thought to be the root cause of all these diseases,
Autor:
Alisha Mavis, Kara Wegermann, Ayako Suzuki, Cynthia A. Moylan, Anna Mae Diehl, Manal F. Abdelmalek
Publikováno v:
Hepatology. 73:1199-1206
Sex and Menopause Modify the Effect of Single Nucleotide Polymorphism Genotypes on Fibrosis in NAFLD
Autor:
Jiayin Zheng, Anna Mae Diehl, Cynthia D. Guy, Ayako Suzuki, Kara Wegermann, Allison E. Ashley-Koch, Shein-Chung Chow, Andrea D. Coviello, Melanie E. Garrett, Cynthia A. Moylan, Manal F. Abdelmalek
Publikováno v:
Hepatology Communications, Vol 5, Iss 4, Pp 598-607 (2021)
Hepatology Communications
Hepatology Communications
The development of fibrosis in nonalcoholic fatty liver disease (NAFLD) is influenced by genetics, sex, and menopausal status, but whether genetic susceptibility to fibrosis is influenced by sex and reproductive status is unclear. Our aim was to iden
Autor:
Marine, Baptissart, Christine M, Bradish, Brie S, Jones, Evan, Walsh, Jesse, Tehrani, Vicmarie, Marrero-Colon, Sanya, Mehta, Dereje D, Jima, Seh Hoon, Oh, Anna Mae, Diehl, Tiffany, Fougeray, Hervé, Guillou, Michael, Cowley
Publikováno v:
Hepatology (Baltimore, Md.). 76(4)
Within the next decade, NAFLD is predicted to become the most prevalent cause of childhood liver failure in developed countries. Predisposition to juvenile NAFLD can be programmed during early life in response to maternal metabolic syndrome (MetS), b
Autor:
Fabian Heinemann, Peter Gross, Svetlana Zeveleva, Hu Sheng Qian, Jon Hill, Anne Höfer, Danny Jonigk, Anna Mae Diehl, Manal Abdelmalek, Martin C. Lenter, Steven S. Pullen, Paolo Guarnieri, Birgit Stierstorfer
Publikováno v:
Scientific reports 12, 19236 (2022). doi:10.1038/s41598-022-23905-3
Scientific reports 12, 19236 (2022). doi:10.1038/s41598-022-23905-3
Published by Macmillan Publishers Limited, part of Springer Nature, [London]
Published by Macmillan Publishers Limited, part of Springer Nature, [London]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cb9e007dff78cbfe9108624437c7d5
Autor:
Rohan Khera, Kara Wegermann, Manal F. Abdelmalek, Kershaw V. Patel, Lin Zhong, Cynthia A. Moylan, Anna Mae Diehl, Robert W. McGarrah, Vishal N. Rao, Ethan A. Halm, Ian J. Neeland, Marat Fudim, Ambarish Pandey, Sandeep R Das, Jeroen Molinger
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 22 (2021)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Nonalcoholic fatty liver disease (NAFLD) and heart failure (HF) are increasing in prevalence. The independent association between NAFLD and downstream risk of HF and HF subtypes (HF with preserved ejection fraction and HF with reduced ejec
Autor:
Anna Mae Diehl, Ning-Ping Zhang, Ying Wang, Chen Yang, Xiuping Liu, Xue-Jing Liu, Wen‐Yue Dong, Chang Liu, Li Xie, Manal F. Abdelmalek, Jian Wu, Chenjian Gu, Kuo Du, Chen Niu
Publikováno v:
Liver Int
Background and aims Treatment of non-alcoholic steatohepatitis (NASH) is challenging, because suppressing fibrotic progression has not been achieved consistently by drug candidates currently in clinical trials. The aim of this study was to investigat
Autor:
Anna Mae Diehl, Oliver Glass, Elizabeth Bechard, Jane F. Pendergast, Cynthia D. Guy, Daniel Liu, Manal F. Abdelmalek
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 6, Iss 2, Pp 334-344 (2022)
Hepatology Communications, Vol 6, Iss 2, Pp 334-344 (2022)
Exercise is a foundational treatment for nonalcoholic fatty liver disease (NAFLD); however, the majority of patients are unable to initiate and maintain effective exercise habits and remain at increased risk for progressive liver disease. Barriers an