Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Karen-Amanda Irvine"'
Autor:
Seok Joon Won, Jayinee Basu, Karen-Amanda Irvine, Robin K Bishop, Raymond A. Swanson, Eric Rome
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Scientific reports, vol 12, iss 1
Scientific Reports
Scientific reports, vol 12, iss 1
Scientific Reports
Blast exposure can injure brain by multiple mechanisms, and injury attributable to direct effects of the blast wave itself have been difficult to distinguish from that caused by rapid head displacement and other secondary processes. To resolve this i
Autor:
Nikos Kyritsis, Jacqueline C. Bresnahan, Karen-Amanda Irvine, John C. Gensel, Rajiv R. Ratan, Jessica L. Nielson, Michael C. Oldham, J.R. Huie, Mark R. Segal, Michael S. Beattie, Jonathan Z. Pan, Amity Lin, Adam R. Ferguson, Patrick G. Schupp
Publikováno v:
Scientific reports, vol 11, iss 1
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
SUMMARYTraumatic spinal cord injury (SCI) produces a complex syndrome that is expressed across multiple endpoints ranging from molecular and cellular changes to functional behavioral deficits. Effective therapeutic strategies for CNS injury are there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d88e3e42b981826baf038dde7aa4fd2
https://escholarship.org/uc/item/75d653j4
https://escholarship.org/uc/item/75d653j4
Autor:
S. Scott Panter, Seok Joon Won, Giordano Fabricio Cittolin-Santos, Robin K Bishop, Eric Rome, Karen-Amanda Irvine, Jayinee Basu, Jianguo Xu, Raymond A. Swanson, Katherine A. Hamel, Andrew Sondag, Valerie G. Coppes, Pardeep Singh
Publikováno v:
Journal of neurotrauma, vol 35, iss 7
The inflammation response induced by brain trauma can impair recovery. This response requires several hours to develop fully and thus provides a clinically relevant therapeutic window of opportunity. Poly(ADP-ribose) polymerase inhibitors suppress in
Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury
Autor:
Karen-Amanda Irvine, Aiwen W. Liu, Jesse Paquette, Geoffrey T. Manley, Adam R. Ferguson, C. Amy Tovar, Jacqueline C. Bresnahan, Wise Young, Tanya C. Petrossian, Jennifer Kloke, Cristian F. Guandique, Michael S. Beattie, John C. Gensel, Gunnar E. Carlsson, Tomoo Inoue, Pek Yee Lum, Jessica L. Nielson
Publikováno v:
Nature communications, vol 6, iss 1
Nature Communications
Nature Communications
Data-driven discovery in complex neurological disorders has potential to extract meaningful syndromic knowledge from large, heterogeneous data sets to enhance potential for precision medicine. Here we describe the application of topological data anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1db33daac087d1219fed5a0c3f93268
https://escholarship.org/uc/item/7pc77332
https://escholarship.org/uc/item/7pc77332
Autor:
Adam R. Ferguson, James W. Grau, Jacqueline C. Bresnahan, Michael S. Beattie, J. Russell Huie, Ellen D. Stuck, Karen-Amanda Irvine, Kuan H. Lee
Publikováno v:
eNeuro, vol 2, iss 5
eNeuro
eNeuro
Clinical spinal cord injury (SCI) is accompanied by comorbid peripheral injury in 47% of patients. Human and animal modeling data have shown that painful peripheral injuries undermine long-term recovery of locomotion through unknown mechanisms. Perip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a315aa9641201d343cd648b3adde770f
https://escholarship.org/uc/item/8wd9z71h
https://escholarship.org/uc/item/8wd9z71h
Autor:
Dana M. McTigue, Kim D. Anderson, V. Reggie Edgerton, Karen-Amanda Irvine, Ephron S. Rosenzweig, Grégoire Courtine, Sharon Zdunowski, Stephanie Hawbecker, Scott R. Whittemore, John C. Gensel, Rod Moseanko, Yvette S. Nout-Lomas, Michael S. Beattie, Jessica L. Nielson, David S.K. Magnuson, Mark R. Segal, Phillip G. Popovich, John H. Brock, Aiwen W. Liu, Stephen W. Scheff, Alexander G. Rabchevsky, Jacqueline C. Bresnahan, Darlene A. Burke, Oswald Steward, Adam R. Ferguson, Sarah C. Strand, Mark H. Tuszynski, Cristian F. Guandique, A. Todd Lash
Publikováno v:
Journal of neurotrauma, vol 31, iss 21
Efforts to understand spinal cord injury (SCI) and other complex neurotrauma disorders at the pre-clinical level have shown progress in recent years. However, successful translation of basic research into clinical practice has been slow, partly becau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09b32055625df4551c4b550a1ff60d9
https://europepmc.org/articles/PMC4186058/
https://europepmc.org/articles/PMC4186058/