Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Wei-Yi Ong"'
Autor:
Venetia Kok Jing Tong, Sylvester Wong Shu Ming, Kah-Leong Lim, Ziyin Wang, Rafhanah Banu Bte Abdul Razar, Saravanan Gunaseelan, Sumitra Srimasorn, Wei-Yi Ong, John Jia En Chua
Publikováno v:
Human Molecular Genetics. 30:5-20
FEZ1-mediated axonal transport plays important roles in central nervous system development but its involvement in the peripheral nervous system is not well-characterized. FEZ1 is deleted in Jacobsen syndrome (JS), an 11q terminal deletion development
Autor:
Wei-Yi Ong, Deron R. Herr, Christopher P Chen, Mitchell K.P. Lai, Brenda Wan Shing Lam, Leona Ting Yuke Ho, Wee Siong Chew, Xin Ying Chua, Ping Xiang
Publikováno v:
NeuroMolecular Medicine. 23:47-67
Sphingosine 1-phosphates (S1Ps) are bioactive lipids that mediate a diverse range of effects through the activation of cognate receptors, S1P1-S1P5. Scrutiny of S1P-regulated pathways over the past three decades has identified important and occasiona
Publikováno v:
Molecular Neurobiology
The prefrontal cortex (PFC) is not only important in executive functions, but also pain processing. The latter is dependent on its connections to other areas of the cerebral neocortex, hippocampus, periaqueductal gray (PAG), thalamus, amygdala, and b
Autor:
Jie-Xin Tong, Wei-Yi Ong, Gavin S. Dawe, Eng Shi Ong, Suku-Maran Shalini, Yee-Kong Ng, Christabel Fung-Yih Ho, Deron R. Herr
Publikováno v:
Molecular Neurobiology
Docosahexaenoic acid (DHA) is enriched in membrane phospholipids of the central nervous system (CNS) and has a role in aging and neuropsychiatric disorders. DHA is metabolized by the enzyme Alox15 to 17S-hydroxy-DHA, which is then converted to 7S-hyd
Publikováno v:
Molecular Neurobiology. 54:6032-6045
Pain and anxiety have a complex relationship and pain is known to share neurobiological pathways and neurotransmitters with anxiety. Top-down modulatory pathways of pain have been shown to originate from cortical and subcortical regions, including th
Autor:
Jui Sheng Wu, Mei-Han Kao, Teng-Nan Lin, Jin Jer Chen, Wei-Yi Ong, Grace Y. Sun, Hsin-Da Tsai
Publikováno v:
NeuroMolecular Medicine. 18:274-282
Many population-based epidemiological studies have unveiled an inverse correlation between intake of herbal plants and incidence of stroke. C. nutans is a traditional herbal medicine widely used for snake bite, viral infection and cancer in Asian cou
Autor:
Hsin Da Tsai, Wei-Yi Ong, Grace Y. Sun, Jin Jer Chen, Teng-Nan Lin, Jui Sheng Wu, Wai-Mui Cheung, Mei-Han Kao
Publikováno v:
Molecular neurobiology. 55(7)
Clinacanthus nutans Lindau (C. nutans) is a traditional herbal medicine widely used in Asian countries for treating a number of remedies including snake and insect bites, skin rashes, viral infections, and cancer. However, the underlying molecular me
Autor:
Bamaprasad Dutta, Yu-Ying Ng, Siu Kwan Sze, Angela Jin-Rong Tan, Wee Siong Chew, Federico Torta, Deron R. Herr, Sneha Muralidharan, Laura Hui-Ru Tan, John Jia En Chua, Wei-Yi Ong
Publikováno v:
Molecular neurobiology. 55(7)
Sphingomyelinases are a family of enzymes that hydrolyze sphingomyelin to generate phosphocholine and ceramide. The brain distribution and function of neutral sphingomyelinase 2 (nSMase2) were elucidated in this study. nSMase2 mRNA expression was gre
Publikováno v:
Neurochemical Research. 38:753-760
Phospholipases A(2) (PLA(2)) are enzymes that cleave the sn-2 bond of membrane phospholipids to yield free fatty acids and lysophospholipids. Secretory PLA2-III (sPLA(2)-III) has been suggested to be important for neuronal differentiation, growth and
Publikováno v:
Neuromolecular medicine. 18(3)