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The dorsal cochlear nucleus (DCN) is a region known to integrate somatosensory and auditory inputs and is identified as a potential key structure in the generation of phantom sound perception, especially noise-induced tinnitus. Yet, how altered homeo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e267e3106a10018580cf8fc525afafc0
https://doi.org/10.1101/2021.04.06.438667
https://doi.org/10.1101/2021.04.06.438667
Autor:
Klas Kullander, Steven J. Edwards, Thawann Malfatti, Katarina E. Leão, Markus M. Hilscher, Barbara Ciralli, Richardson N. Leão
Publikováno v:
Repositório Institucional da UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
eNeuro
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
eNeuro
Visual Abstract
The dorsal cochlear nucleus (DCN) is a region of particular interest for auditory and tinnitus research. However, lack of useful genetic markers for in vivo manipulations hinders elucidation of the DCN contribution to tinnitus pa
The dorsal cochlear nucleus (DCN) is a region of particular interest for auditory and tinnitus research. However, lack of useful genetic markers for in vivo manipulations hinders elucidation of the DCN contribution to tinnitus pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03ffd3246bfe07ff2bebfebf2412194
https://repositorio.ufrn.br/handle/123456789/31566
https://repositorio.ufrn.br/handle/123456789/31566
Autor:
Katarina E. Leão, Jessica Winne, Rafael Franzon, Thawann Malfatti, Aron de Miranda, João H.N. Patriota, Sanja Mikulovic, Richardson N. Leão
Publikováno v:
Repositório Institucional da UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
Salicylate intoxication is a cause of tinnitus in humans and it is often used to produce tinnitus-like perception in animal models. Here, we assess whether salicylate induces anxiety-like electrophysiological and behavioral signs. Using microwire ele
Autor:
Katarina E. Leão, Jessica Winne, Richardson N. Leão, Thawann Malfatti, Thiago Z. Lima, Ingrid Nogueira
Loud noise-exposure generates tinnitus in both humans and animals. Macroscopic studies show that noise exposure affects the auditory cortex; however, cellular mechanisms of tinnitus generation are unclear. Here we compare membrane properties of layer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd061fdfc1e3c5b33f46bf8b4eb12679
https://doi.org/10.1101/2020.08.25.264200
https://doi.org/10.1101/2020.08.25.264200
Autor:
Hilscher, Markus M.1,2 markus.hilscher@neuro.ufrn.br, Leão, Richardson N.1,2, Edwards, Steven J.1, Leão, Katarina E.2, Kullander, Klas1 klas.kullander@neuro.uu.se
Publikováno v:
PLoS Biology. 2/9/2017, Vol. 15 Issue 2, p1-26. 26p.
Autor:
Richardson N. Leão, Dakota Jackson, Geetha Srinivasan, Henrique von Gersdorff, Andre Dagostin, Veeramuthu Balakrishnan, Paul Holcomb, George Spirou
Principal cells of the medial nucleus of the trapezoid body (MNTB) in the mammalian auditory brainstem receive most of their strong synaptic inputs directly on the cell soma. However, these neurons also grow extensive dendrites during the first four
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69877f1dba20b85cd489ae4c98bd44b
https://doi.org/10.1101/688309
https://doi.org/10.1101/688309
Autor:
Ingrid Nogueira, Markus M. Hilscher, Klas Kullander, Sanja Mikulovic, Richardson N. Leão, Katarina E. Leão
Publikováno v:
Repositório Institucional da UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
The hippocampus is an extended structure displaying heterogeneous anatomical cell layers along its dorsoventral axis. It is known that dorsal and ventral regions show different integrity when it comes to functionality, innervation, gene expression, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16331de9f6eba439a0fbd2be67089fd7
https://repositorio.ufrn.br/jspui/handle/123456789/27632
https://repositorio.ufrn.br/jspui/handle/123456789/27632
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Frontiers in Molecular Neuroscience, Vol 12 (2019)
The subgranular zone (SGZ) of dentate gyrus (DG) is one of the few regions in which neurogenesis is maintained throughout adulthood. It is believed that newborn neurons in this region encode temporal information about partially overlapping contextual
Autor:
Lyvia Lintzmaier Petiz, Olavo B. Amaral, Jessica Winne, Thiago C. Moulin, Rafael V. Lima da Cruz, Richardson N. Leão, Danielle Rayêe, Roberto G. Maia
Publikováno v:
Repositório Institucional da UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
Prolonged increases in excitation can trigger cell-wide homeostatic responses in neurons, altering membrane channels, promoting morphological changes and ultimately reducing synaptic weights. However, how synaptic downscaling interacts with classical
Autor:
Helton Maia Peixoto, Klas Kullander, George Carlos do Nascimento, Sanja Mikulovic, Stefano Pupe, Richardson N. Leão, Adriano B. L. Tort
Publikováno v:
Repositório Institucional da UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
Optogenetics allows light activation of genetically defined cell populations and the study of their link to specific brain functions. While it is a powerful method that has revolutionized neuroscience in the last decade, the shortcomings of directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64024785a1b1b73a9768f78bf46e20f
https://repositorio.ufrn.br/jspui/handle/123456789/29645
https://repositorio.ufrn.br/jspui/handle/123456789/29645