Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Merryn Brettle"'
Autor:
Merryn Brettle, Holly Stefen, Aleksandra Djordjevic, Sandra Y. Y. Fok, Josephine W. Chan, Annika van Hummel, Julia van der Hoven, Magdalena Przybyla, Alexander Volkerling, Yazi D. Ke, Fabien Delerue, Lars M. Ittner, Thomas Fath
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with limited treatment and no cure. Mutations in profilin 1 were identified as a cause of familial ALS (fALS) in 2012. We investigated the functional impact of mutant prof
Autor:
Rosanna Herold, Thomas Fath, Shrujna Patel, Merryn Brettle, Esmeralda Paric, Tamara Tomanic, Sandra Fok, Aleksandra Djordjevic, Holly Stefen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0187979 (2017)
PLoS ONE, Vol 12, Iss 11, p e0187979 (2017)
Genetically encoded filamentous actin probes, Lifeact, Utrophin and F-tractin, are used as tools to label the actin cytoskeleton. Recent evidence in several different cell types indicates that these probes can cause changes in filamentous actin dynam
Publikováno v:
Neuroscience letters. 609
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease and familial ALS accounts for 10% of cases. The identification of familial ALS mutations in the actin-binding protein profilin 1 directly implicates actin dynamics and regula