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pro vyhledávání: '"Christine Hui Shan Chan"'
Autor:
Patrick Ho, Tit Meng Lim, Zhi Dong Zhou, Shin Hui Ng, Christine Hui Shan Chan, Xiao-Dong Zhang, Shao Ping Xie, Fathima Shaffra Refai, Eng-King Tan
Publikováno v:
Free radical biologymedicine. 68
PINK1 mutations cause autosomal recessive forms of Parkinson disease (PD). Previous studies suggest that the neuroprotective function of wild-type (WT) PINK1 is related to mitochondrial homeostasis. PINK1 can also localize to the cytosol; however, th
Autor:
Eng-King Tan, Xiao-hong Xu, Zhi-Cheng Xiao, Christine Hui Shan Chan, Zhi Dong Zhou, Quan-Hong Ma
Publikováno v:
Cell adhesionmigration. 5(4)
The amyloid-beta (Aβ) peptide is the derivative of amyloid precursor protein (APP) generated through sequential proteolytic processing by β- and γ-secretases. Excessive accumulation of Aβ, the main constituent of amyloid plaques, has been implica