Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Chris I. De Zeeuw"'
Autor:
Bin-Bin Dong, Lin Zhou, Xin-Tai Wang, Fang-Xiao Xu, De-Juan Wang, En-Wei Shen, Xin-Yu Cai, Yin Wang, Na Wang, Sheng-Jian Ji, Wei Chen, Martijn Schonewille, J Julius Zhu, Chris I De Zeeuw, Ying Shen
Publikováno v:
eLife, 12:e80875. eLife Sciences Publications
The cerebellum is involved in learning of fine motor skills, yet whether presynaptic plasticity contributes to such learning remains elusive. Here, we report that the EPAC-PKCε module has a critical role in a presynaptic form of long-term potentiati
Autor:
Sadaf Soloukey, Andreas Rowald, Claudia Kathe, Ivan Furfaro, Philipp Schonle, Valentina Paggi, Quentin Barraud, Stéphanie P. Lacour, Jimmy Ravier, Qiuting Huang, Kyungjin Kim, Thomas H. Hutson, Ileana O. Jelescu, Antoine Philippides, Noaf Salah Ali Alwahab, Chris I. De Zeeuw, Daniel Huber, Frédéric Michoud, Leonie Asboth, Noe Brun, Jerome Gandar, Grégoire Courtine
Publikováno v:
Nature Biotechnology, 40 (2)
Nature Biotechnology, 40(2), 198-208. Nature Publishing Group
Nature Biotechnology, 40, 198-208. Nature Publishing Group
Nature Biotechnology, 40(2), 198-208. Nature Publishing Group
Nature Biotechnology, 40, 198-208. Nature Publishing Group
Optoelectronic systems can exert precise control over targeted neurons and pathways throughout the brain in untethered animals, but similar technologies for the spinal cord are not well established. In the present study, we describe a system for ultr
Publikováno v:
Journal of Neuroscience Research, 100(2), 620-637. Wiley-Liss Inc.
Journal of Neuroscience Research
Journal of Neuroscience Research, 100, 620-637. Wiley-Liss Inc.
Journal of Neuroscience Research
Journal of Neuroscience Research, 100, 620-637. Wiley-Liss Inc.
Most studies investigating the impact of the cerebral cortex (CC) onto the cerebellum highlight the role of the pons, which provides the mossy fibers to the cerebellum. However, cerebro-cerebellar communication may also be mediated by the nuclei of t
Autor:
Willem S. van Hoogstraten, Marit C. C. Lute, Hugo Nusselder, Lieke Kros, Arn M. J. M. van den Maagdenberg, Chris I. De Zeeuw
Publikováno v:
Cells; Volume 11; Issue 19; Pages: 2978
Cells, 11(19):2978. Multidisciplinary Digital Publishing Institute (MDPI)
Cells, 11(19). MDPI
Cells, 11(19). Multidisciplinary Digital Publishing Institute (MDPI)
Cells, 11(19):2978. Multidisciplinary Digital Publishing Institute (MDPI)
Cells, 11(19). MDPI
Cells, 11(19). Multidisciplinary Digital Publishing Institute (MDPI)
Over the past decades, it has become increasingly clear that many neurodevelopmental disorders can be characterized by aberrations in the neuro-anatomical connectome of intermediary hubs. Yet, despite the advent in unidirectional transsynaptic tracin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6110bbb449b99cacbaaa32afa4223c72
https://doi.org/10.3390/cells11192978
https://doi.org/10.3390/cells11192978
Autor:
Peter Holland, Sade J. Faneyte, Lieke Kros, Oscar H J Eelkman Rooda, Nico A Jansen, Freek E. Hoebeek, Else A. Tolner, Arn M. J. M. van den Maagdenberg, Chris I. De Zeeuw, Huub J Poelman, Simona V. Gornati
Publikováno v:
Brain Stimulation, 14(4), 861-872. Elsevier Inc.
Brain Stimulation, 14, 861-872. Elsevier B.V.
Brain Stimulation, Vol 14, Iss 4, Pp 861-872 (2021)
Brain Stimulation, 14(4), 861-872. ELSEVIER SCIENCE INC
Brain Stimulation, 14, 861-872. Elsevier B.V.
Brain Stimulation, Vol 14, Iss 4, Pp 861-872 (2021)
Brain Stimulation, 14(4), 861-872. ELSEVIER SCIENCE INC
Background: Epileptic (absence) seizures in the cerebral cortex can be stopped by pharmacological and optogenetic stimulation of the cerebellar nuclei (CN) neurons that innervate the thalamus. However, it is unclear how such stimulation can modify un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab79c00e7c2dce542e2b8588aaa9609c
https://pure.eur.nl/en/publications/87c05df5-4a9c-4cb9-8bfb-4f6604345a48
https://pure.eur.nl/en/publications/87c05df5-4a9c-4cb9-8bfb-4f6604345a48
Autor:
Sebastian Loyola, Nikolay Medvedev, Ben Torben-Nielsen, Mario Negrello, Nora Vrieler, Marylka Uusisaari, Chris I. De Zeeuw, Yosef Yarom, Yasmin Yarden-Rabinowitz, Jesse Hoogendorp, Tycho M. Hoogland, Erik De Schutter
Publikováno v:
Brain Structure & Function
Brain Structure & Function, 224(4), 1677-1695. Springer-Verlag
Brain Structure & Function, 224, 1677-1695. Springer Verlag GmbH
Brain Structure & Function, 224(4), 1677-1695. Springer-Verlag
Brain Structure & Function, 224, 1677-1695. Springer Verlag GmbH
The inferior olive (IO) is an evolutionarily conserved brain stem structure and its output activity plays a major role in the cerebellar computation necessary for controlling the temporal accuracy of motor behavior. The precise timing and synchroniza
Autor:
Chris I. De Zeeuw, Amada M. Abrego, Zhenyu Gao, Courtney Davis, Michael N. Economo, Nuo Li, Alyse M. Thomas, Karel Svoboda
Publikováno v:
Nature, 563(7729), 113-+. Nature Publishing Group
Nature, 563, 113-116. Nature Publishing Group
Nature
Nature, 563, 113-116. Nature Publishing Group
Nature
Persistent and ramping neural activity in the frontal cortex anticipates specific movements1–6. Preparatory activity is distributed across several brain regions7,8, but it is unclear which brain areas are involved and how this activity is mediated
Autor:
Henk-Jan Boele, Daniela Carulli, Fred de Winter, Maja Meškovic, Elizabeth M. Muir, Sharon de Vries, Matthijs de Waal, Cathrin B. Canto, Joost Verhaagen, Chris I. De Zeeuw, Robin Broersen
Publikováno v:
Carulli, D, Broersen, R, de Winter, F, Muir, E M, Meškovic, M, de Waal, M, de Vries, S, Boele, H J, Canto, C B, de Zeeuw, C I & Verhaagen, J 2020, ' Cerebellar plasticity and associative memories are controlled by perineuronal nets ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 12, pp. 6855-6865 . https://doi.org/10.1073/pnas.1916163117
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 117, 6855-6865. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(12), 6855-6865. National Acad Sciences
Proceedings of the National Academy of Sciences of the U.S.A., 117(12), 6855-6865. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 117, 6855-6865. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(12), 6855-6865. National Acad Sciences
Proceedings of the National Academy of Sciences of the U.S.A., 117(12), 6855-6865. National Academy of Sciences
Significance Understanding mechanisms underlying learning and memory is crucial in view of tackling cognitive decline occurring during aging or following neurological disorders. The cerebellum offers an ideal system to achieve this goal because of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef873295214d63f6a2e4b686f02432f
https://hdl.handle.net/1871.1/8b5ab303-7593-4684-9b9a-0cc6a1826866
https://hdl.handle.net/1871.1/8b5ab303-7593-4684-9b9a-0cc6a1826866
Autor:
Chris I. De Zeeuw, Martijn Schonewille, Lisa van Beers, Silas E. Busch, Lindsey Jay, Gerco C. Beekhof, Giorgio Grasselli, Heather K. Titley, Christian Hansel, Nora Bradford, Henk-Jan Boele
Publikováno v:
PLoS Biology (print), 18(1):e3000596. Public Library of Science
PLoS Biology, 18(1). Public Library of Science
PLoS Biology
PLoS Biology, Vol 18, Iss 1, p e3000596 (2020)
PLoS Biology, 18(1). Public Library of Science
PLoS Biology
PLoS Biology, Vol 18, Iss 1, p e3000596 (2020)
Neurons store information by changing synaptic input weights. In addition, they can adjust their membrane excitability to alter spike output. Here, we demonstrate a role of such “intrinsic plasticity” in behavioral learning in a mouse model that
Autor:
Mark Bradley, Guy Shpak, Suvra Nath, Yichuan Zhang, Jeffrey Matray, Lidy E. Fratila-Apachitei, Chris I. De Zeeuw, Amir A. Zadpoor, Steven A. Kushner, Seshasailam Venkateswaran, Gustavo A. Higuera
Publikováno v:
Advanced Healthcare Materials, 9(4)
Zhang, Y, Venkateswaran, S, Higuera, G A, Nath, S, Shpak, G, Matray, J, Fratila-apachitei, L E, Zadpoor, A A, Kushner, S A, Bradley, M & De Zeeuw, C I 2020, ' Synthetic Polymers Provide a Robust Substrate for Functional Neuron Culture ', Advanced Healthcare Materials, pp. 1901347 . https://doi.org/10.1002/adhm.201901347
Advanced healthcare materials, 9. John Wiley and Sons Ltd
Advanced healthcare materials, 9(4):e1901347. John Wiley & Sons Ltd.
Zhang, Y, Venkateswaran, S, Higuera, G A, Nath, S, Shpak, G, Matray, J, Fratila-apachitei, L E, Zadpoor, A A, Kushner, S A, Bradley, M & De Zeeuw, C I 2020, ' Synthetic Polymers Provide a Robust Substrate for Functional Neuron Culture ', Advanced Healthcare Materials, pp. 1901347 . https://doi.org/10.1002/adhm.201901347
Advanced healthcare materials, 9. John Wiley and Sons Ltd
Advanced healthcare materials, 9(4):e1901347. John Wiley & Sons Ltd.
Substrates for neuron culture and implantation are required to be both biocompatible and display surface compositions that support cell attachment, growth, differentiation, and neural activity. Laminin, a naturally occurring extracellular matrix prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2957ea1d5fa09abf359577a2b1c99d
http://resolver.tudelft.nl/uuid:0711096c-c47e-464b-a59a-8282bb306423
http://resolver.tudelft.nl/uuid:0711096c-c47e-464b-a59a-8282bb306423