Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Doron Merkler"'
Autor:
Andreas Agrafiotis, Raphael Dizerens, Ilena Vincenti, Ingrid Wagner, Raphael Kuhn, Danielle Shlesinger, Marcos Manero-Carranza, Tudor-Stefan Cotet, Kai-Lin Hong, Nicolas Page, Nicolas Fonta, Ghazal Shammas, Alexandre Mariotte, Margot Piccinno, Mario Kreutzfeldt, Benedikt Gruntz, Roy Ehling, Alessandro Genovese, Alessandro Pedrioli, Andreas Dounas, Sören Franzenburg, Hayrettin Tumani, Tania Kümpfel, Vladyslav Kavaka, Lisa Ann Gerdes, Klaus Dornmair, Eduardo Beltrán, Annette Oxenius, Sai T. Reddy, Doron Merkler, Alexander Yermanos
Publikováno v:
Acta Neuropathologica. 145:335-355
B cells contribute to the pathogenesis of both cellular- and humoral-mediated central nervous system (CNS) inflammatory diseases through a variety of mechanisms. In such conditions, B cells may enter the CNS parenchyma and contribute to local tissue
Autor:
Giovanni Di Liberto, Kristof Egervari, Mario Kreutzfeldt, Christian M Schürch, Ekkehard Hewer, Ingrid Wagner, Renaud Du Pasquier, Doron Merkler
Publikováno v:
Di Liberto, Giovanni; Egervari, Kristof; Kreutzfeldt, Mario; Schürch, Christian M; Hewer, Ekkehard; Wagner, Ingrid; Du Pasquier, Renaud; Merkler, Doron (2022). Neurodegenerative phagocytes mediate synaptic stripping in Neuro-HIV. Brain : a journal of neurology, 145(8), pp. 2730-2741. Oxford University Press 10.1093/brain/awac102
Glial cell activation is a hallmark of several neurodegenerative and neuroinflammatory diseases. During HIV infection, neuroinflammation is associated with cognitive impairment, even during sustained long-term suppressive antiretroviral therapy. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee1fd625074c07271c7c6fda4d606d3a
Autor:
Nedelina Slavova, Ekkehard Hewer, Kristof Egervari, Eike I. Piechowiak, Doron Merkler, Konstantin Bräutigam, Beatrice Mosimann
Publikováno v:
Brain tumor pathology
Brain Tumor Pathology (2020)
Brain Tumor Pathology (2020)
Publikováno v:
Nature reviews. Neurology. 17(7)
The pathophysiology of complex neuroimmunological diseases, such as multiple sclerosis and autoimmune encephalitis, remains puzzling - various mechanisms that are difficult to dissect seem to contribute, hampering the understanding of the processes i
Autor:
Anja Schmalz, Mario Kreutzfeldt, Anne Jacobi, Florence M. Bareyre, Kristina Loy, Tobias Hoche, Doron Merkler
Publikováno v:
Journal of Neurotrauma, Vol. 35, No 24 (2018) pp. 2904-2915
Recent reports suggest that rehabilitation measures that increase physical activity of patients can improve functional outcome after incomplete spinal cord injuries (iSCI). To investigate the structural basis of exercise-induced recovery, we examined
Autor:
Thomas Höllbacher, Wolfgang Brück, Klaus Seelos, Tania Kümpfel, Matthias Mäurer, Nathalie L. Albert, Imke Metz, Achim Gass, Christine Stadelmann, Birgit Ertl-Wagner, Christoph Mahler, Joachim Havla, Markus Krumbholz, Maximilian Patzig, Peter Bartenstein, Julia Neitzel, Vladimir M. Milenkovic, Doron Merkler, Simon Lindner, Marcus Unterrainer, Martin Kerschensteiner, Adrian-Minh Schumacher, Lena Kaiser
Publikováno v:
Brain (2021)
Progressive multifocal leukoencephalopathy (PML) is a severe infection of the CNS caused by the polyomavirus JC that can occur in multiple sclerosis patients treated with natalizumab. Clinical management of patients with natalizumab-associated PML is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a59711c2e96c877252f783cf38ea77
https://archive-ouverte.unige.ch/unige:151695
https://archive-ouverte.unige.ch/unige:151695
Autor:
Ingrid Wagner, Dirk H. Busch, Giovanni Di Liberto, Simon P. Fräßle, Sarah Dötsch, Thomas Korn, Christopher Sie, Doron Merkler, Benjamin Knier, Meike Mitsdoerffer, Lilian Aly, Mario Kreutzfeldt, Monika Pfaller
Publikováno v:
Brain (2021)
Brain
Brain
Meningeal B lymphocyte aggregates have been described in autopsy material of patients with chronic multiple sclerosis. The presence of meningeal B cell aggregates has been correlated with worse disease. However, the functional role of these meningeal
Autor:
Nina Steinemann, Jens Kuhle, Pasquale Calabrese, Jürg Kesselring, Giulio Disanto, Doron Merkler, Caroline Pot, Vladeta Ajdacic-Gross, Stephanie Rodgers, Milo Alan Puhan, Viktor von Wyl, the Swiss Multiple Sclerosis Registry
Publikováno v:
BMC Neurology, Vol 18, Iss 1, Pp 1-10 (2018)
BMC neurology, vol. 18, no. 1, pp. 111
BMC Neurology
Steinemann, Nina; Kuhle, Jens; Calabrese, Pasquale; Kesselring, Jürg; Disanto, Giulio; Merkler, Doron; Pot, Caroline; Ajdacic-Gross, Vladeta; Rodgers, Stephanie; Puhan, Milo Alan; von Wyl, Viktor (2018). The Swiss Multiple Sclerosis Registry (SMSR): study protocol of a participatory, nationwide registry to promote epidemiological and patient-centered MS research. BMC neurology, 18(1), p. 111. BioMed Central 10.1186/s12883-018-1118-0
BMC Neurology, Vol. 18, No 1 (2018) P. 111
BMC neurology, vol. 18, no. 1, pp. 111
BMC Neurology
Steinemann, Nina; Kuhle, Jens; Calabrese, Pasquale; Kesselring, Jürg; Disanto, Giulio; Merkler, Doron; Pot, Caroline; Ajdacic-Gross, Vladeta; Rodgers, Stephanie; Puhan, Milo Alan; von Wyl, Viktor (2018). The Swiss Multiple Sclerosis Registry (SMSR): study protocol of a participatory, nationwide registry to promote epidemiological and patient-centered MS research. BMC neurology, 18(1), p. 111. BioMed Central 10.1186/s12883-018-1118-0
BMC Neurology, Vol. 18, No 1 (2018) P. 111
Multiple sclerosis (MS) is one of the most frequently observed neurological conditions in Switzerland, but data sources for country-wide epidemiological trend monitoring are lacking. Moreover, while clinical and laboratory MS research are generally w
Autor:
Mario Kreutzfeldt, Doron Merkler, Meike Mitsdoerffer, Monika Pfaller, Ingrid Wagner, Giovanni Di Liberto, Benjamin Knier, Christopher Sie, Dirk H. Busch, Simon P. Fräßle, Lilian Aly, Sarah Dötsch, Thomas Korn
Publikováno v:
Brain. 144:e83-e83
Publikováno v:
Multiple Sclerosis and Related Disorders, Vol. 34 (2019) pp. 63-65
Background Fingolimod is the first approved oral disease-modifying treatment for relapsing-remitting multiple sclerosis. Fingolimod targets lymphocytes, exerting a modulator effect on cell-surface sphingosine-1-phosphate receptors and thus blocking l