Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Aruna Chakrabarty"'
Autor:
Moritz W. J. Schramm, Stuart Currie, Ming-te Lee, Laurent J. Livermore, Sandeep P. Solanki, Ryan K. Mathew, Heiko Wurdak, Mihaela Lorger, Chris Twelves, Susan C. Short, Aruna Chakrabarty, Paul Chumas
Publikováno v:
Journal of Neuro-Oncology. 161:451-467
Introduction Brain tumors cause morbidity and mortality in part through peritumoral brain edema. The current main treatment for peritumoral brain edema are corticosteroids. Due to the increased recognition of their side-effect profile, there is growi
Autor:
Shoaib Ajaib, Disha Lodha, Steven Pollock, Gemma Hemmings, Martina A. Finetti, Arief Gusnanto, Aruna Chakrabarty, Azzam Ismail, Erica Wilson, Frederick S Varn, Bethany Hunter, Andrew Filby, Asa A. Brockman, David McDonald, Roel GW Verhaak, Rebecca A. Ihrie, Lucy F. Stead
Publikováno v:
Neuro-Oncology.
The biological and clinical impact of neoplastic and immune cell type ratios in the glioblastoma (GBM) tumour microenvironment is being realised. Characterising and quantifying cell types within GBMs at scale will facilitate a better understanding of
Autor:
Georgette Tanner, Martina A Finetti, Steven Pollock, Nora Rippaus, Alexander-Francisco Bruns, Catherine Hogg, Alastair Droop, Anke Bruning-Richardson, Mathew Care, Joseph Wilkinson, Michael Jenkinson, Andrew Brodbelt, Aruna Chakrabarty, Azzam Ismail, Susan Short, Lucy Stead
Publikováno v:
Neuro-Oncology. 24:iv1-iv1
AIMS Glioblastoma (GBM) is the most common primary malignant brain tumour in adults. Despite aggressive treatment, a resistant tumour recurs in practically all patients. We therefore aimed to better understand the mechanisms driving this treatment re
Autor:
Jochen Walter, Aruna Chakrabarty, Christine A. F. von Arnim, Adrian Smith, Kerstin Heurling, Thomas G. Beach, Azzam Ismail, Mathieu Vandenbulcke, Ajeet Rijal Upadhaya, Johan Lilja, Karthikeyan Balakrishnan, Gill Farrar, Rik Vandenberghe, Sathish Kumar, Alicja Ronisz, Thomas Tousseyn, Christopher Buckley, Markus Otto, Dietmar Rudolf Thal
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-3 (2020)
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-3 (2020)
Alzheimer’s disease (AD)-related amyloid β-peptide (Aβ) pathology in the form of amyloid plaques and cerebral amyloid angiopathy (CAA) spreads in its topographical distribution, increases in quantity, and undergoes qualitative changes in its comp
Autor:
Gill Farrar, Michelle Zanette, Adrian Smith, Kerstin Heurling, Johan Lilja, Dietmar Rudolf Thal, Aruna Chakrabarty, Thomas G. Beach, Azzam Ismail, Christopher Buckley
Publikováno v:
Acta Neuropathologica
The deposition of the amyloid β-protein (Aβ) in senile plaques is one of the histopathological hallmarks of Alzheimer’s disease (AD). Aβ-plaques arise first in neocortical areas and, then, expand into further brain regions in a process described
Autor:
Aruna Chakrabarty, Alastair Droop, Azzam Ismail, Muna Al-Jabri, Matthew A. Care, Susan C Short, Lucy F. Stead, Michael D. Jenkinson, Alexander-F Bruns, Nora Rippaus, Andrew Brodbelt
Publikováno v:
Neuro Oncol
Recent findings from our group, and the wider community, show that standard treatment does not impose an apparent bottleneck on the clonal evolution of adult glioblastoma (GBM), implying a lack of direct therapeutic opportunity. This does not negate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd77c1a9650952b43188ddbd7bb8ac7e
https://eprints.whiterose.ac.uk/162285/1/Bruns.docx
https://eprints.whiterose.ac.uk/162285/1/Bruns.docx
Autor:
Zhuowen Geng, Alna Dony, Neeraj Kalra, Ryan K. Mathew, Aruna Chakrabarty, Helen Bailey, Paul Roberts
Publikováno v:
Neuro-Oncology. 23:vi126-vi126
INTRODUCTION In 2016 the WHO Classification of Tumours of the Central Nervous System was updated to include molecular testing, in addition to the previous standard histological methods; producing a final integrated diagnosis. Although molecular infor
Autor:
Lucy F. Stead, Michael D. Jenkinson, J Manning, Susan C Short, Andrew Brodbelt, Matthew A. Care, Aruna Chakrabarty, M Al-Jabri, Alexander-Francisco Bruns, Alastair Droop, Azzam Ismail, Nora Rippaus
Publikováno v:
Neuro Oncol
BACKGROUND Glioblastoma (GBM) tumours recur following standard treatment in almost all cases. We use ‘omics technologies to simultaneously profile pairs of primary and matched recurrent GBM to specifically identify and characterise the cells that r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ea6825e971b705d08bb8a537479c20
https://eprints.whiterose.ac.uk/162286/1/Rippaus_EANO2019abstract.docx
https://eprints.whiterose.ac.uk/162286/1/Rippaus_EANO2019abstract.docx
Autor:
Richard G. Feltbower, Aruna Chakrabarty, Ryan K. Mathew, Carmel Loughrey, Oluwafikayo Fayeye, Paul Chumas, Edward Goacher
BACKGROUND: Increasing knowledge and understanding of the molecular genetics driving both the occurrence and transformation of gliomas has led to a more discrete and objective classification of such tumours. Both phenotypic and genotypic variations n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebeeb76fa84d989e47c75d2525ff722
https://europepmc.org/articles/PMC6216560/
https://europepmc.org/articles/PMC6216560/
Autor:
Daniel J. O’Hara, Paul Roberts, Azzam Ismail, John Goodden, Hugues Duffau, Tufail Patankar, Martin S. Palin, Carmel Loughrey, Jeremy Macmullen-Price, Paul Chumas, Aruna Chakrabarty, Yahia Z. Al-Tamimi
Publikováno v:
World Neurosurgery
World Neurosurgery, Elsevier, 2018, 110, pp.e346--e354. ⟨10.1016/j.wneu.2017.10.172⟩
World Neurosurgery, Elsevier, 2018, 110, pp.e346--e354. ⟨10.1016/j.wneu.2017.10.172⟩
International audience; BACKGROUND: Low-grade glioma (LGG) is a slow-growing tumor often found in young adults with minimal or no symptoms. As opposed to true low-grade lesions such as dysembryoplastic neuroepithelial tumors, they are associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e700a956b67e439029e6c9426c4c9c
https://hal.archives-ouvertes.fr/hal-01742104
https://hal.archives-ouvertes.fr/hal-01742104