Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jianrong Wu"'
Autor:
Navid F; Fariba Navid, Barry L. Shulkin, Robert A. Kaufman, Catherine A. Billups, Jianrong Wu, Wayne L. Furman, Lisa M. McGregor, and Victor M. Santana, St Jude Children's Research Hospital; Fariba Navid, Robert A. Kaufman, Wayne L. Furman, Lisa M. McGregor, and Victor M. Santana, College of Medicine, University of Tennessee Health Science Center; Jim A. Allay, Children's GMP, Memphis, TN; Paul M. Sondel, Jacek Gan, Paul Hutson, Songwon Seo, KyungMann Kim, Jacob Goldberg, Jacquelyn A. Hank, and Mario Otto, University of Wisconsin, Madison, WI; Raymond Barfield, Duke University Medical Center, Durham, NC; Stephen D. Gillies, Provenance Biopharmaceuticals, Carlisle, MA; and Rupert Handgretinger, University Children's Hospital, Tübingen, Germany., Sondel PM, Barfield R, Shulkin BL, Kaufman RA, Allay JA, Gan J, Hutson P, Seo S, Kim K, Goldberg J, Hank JA, Billups CA, Wu J, Furman WL, McGregor LM, Otto M, Gillies SD, Handgretinger R, Santana VM
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2014 May 10; Vol. 32 (14), pp. 1445-52. Date of Electronic Publication: 2014 Apr 07.
Autor:
Wayne L. Furman, Beth McCarville, Barry L. Shulkin, Andrew Davidoff, Matthew Krasin, Chia-Wei Hsu, Haitao Pan, Jianrong Wu, Rachel Brennan, Michael W. Bishop, Sara Helmig, Elizabeth Stewart, Fariba Navid, Brandon Triplett, Victor Santana, Teresa Santiago, Jacquelyn A. Hank, Stephen D. Gillies, Alice Yu, Paul M. Sondel, Wing H. Leung, Alberto Pappo, Sara M. Federico
Publikováno v:
J Clin Oncol
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 40, iss 4
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 40, iss 4
PURPOSEWe evaluated whether combining a humanized antidisialoganglioside monoclonal antibody (hu14.18K322A) throughout therapy improves early response and outcomes in children with newly diagnosed high-risk neuroblastoma.PATIENTS AND METHODSWe conduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14aa3e91b95eda27a59cc722c2a8323a
https://europepmc.org/articles/PMC8797508/
https://europepmc.org/articles/PMC8797508/
Autor:
Wayne L. Furman, Fariba Navid, Wing Leung, Alice L. Yu, Matthew J. Krasin, Alberto S. Pappo, Gwendolyn Anthony, Barry L. Shulkin, Armita Bahrami, Stephen D. Gillies, Victor M. Santana, Mary Beth McCarville, Elizabeth Stewart, Michael W. Bishop, Jacquelyn A. Hank, Sara M. Federico, Paul M. Sondel, Rachel C. Brennan, Natasha Sahr, Jianrong Wu, Sara Helmig, April Sykes, Andrew M. Davidoff, Brandon M. Triplett
Publikováno v:
Clin Cancer Res
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 25, iss 21
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 25, iss 21
Purpose: We sought to evaluate whether combining a humanized antidisialoganglioside mAb (hu14.18K322A) with induction chemotherapy improves early responses and outcomes in children with newly diagnosed high-risk neuroblastoma. Patients and Methods: W
Autor:
Heather L. Mulder, Peter Vogel, Steven Henikoff, Marcin Kamiński, Richard K. Wilson, Jinghui Zhang, Anang A. Shelat, James R. Downing, Marc Valentine, Yanling Liu, Xin Zhou, Yiping Fan, Armita Bahrami, Arlene Naranjo, Collin Van Ryn, Rani E. George, Sara M. Federico, Beisi Xu, Jongrye Jeon, Seungjae Lee, Xiang Chen, Elizabeth Stewart, John Easton, Donald Yergeau, Shondra M. Pruett-Miller, Jay F. Sarthy, Michael P. Meers, Maged Zeineldin, Michael A. Dyer, Lyra Griffiths, Michael R. Clay, Jackie L. Norrie, Elaine R. Mardis, Rosa Nguyen, Alberto S. Pappo, Michael D. Hogarty, Jianrong Wu
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Aggressive cancers often have activating mutations in growth-controlling oncogenes and inactivating mutations in tumor-suppressor genes. In neuroblastoma, amplification of the MYCN oncogene and inactivation of the ATRX tumor-suppressor gene correlate
Autor:
Rachel C. Brennan, Barry L. Shulkin, Shenghua Mao, Alberto S. Pappo, Paul M. Sondel, M. Beth McCarville, Wayne L. Furman, Victor M. Santana, Wing Leung, Catherine Y.C. Ng, Paul R. Hutson, William E. Janssen, Aaron Shafer, Sara M. Federico, Michael M Meagher, Jianrong Wu, Jacquelyn A. Hank
Publikováno v:
Clin Cancer Res
Purpose: Anti-GD2 mAbs, acting via antibody-dependent cell-mediated cytotoxicity, may enhance the effects of chemotherapy. This pilot trial investigated a fixed dose of a unique anti-GD2 mAb, hu14.18K322A, combined with chemotherapy, cytokines, and h
Autor:
Seungjae Lee, Elizabeth Stewart, James R. Downing, Armita Bahrami, Heather L. Mulder, Marc Valentine, Jianrong Wu, Rani E. George, Donald Yergeau, Michael D. Hogarty, Maged Zeineldin, Elaine R. Mardis, Xin Zhou, Sara M. Federico, Beisi Xu, Anang A. Shelat, Richard K. Wilson, Yanling Liu, Jinghui Zhang, Jongrye Jeon, Arlene Naranjo, Shondra M. Pruett-Miller, John Easton, Michael R. Clay, Collin Van Ryn, Lyra Griffiths, Xiang Chen, Yiping Fan, Marcin Kamiński, Alberto S. Pappo, Michael A. Dyer
SUMMARYAggressive cancers often have activating mutations in growth-controlling oncogenes and inactivating mutations in tumor-suppressor genes. In neuroblastoma, amplification of the MYCN oncogene and inactivation of the ATRX tumor-suppressor gene co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9c9691bc389d4e691e3cbd0c5b70af
https://doi.org/10.1101/379636
https://doi.org/10.1101/379636
Autor:
Shenghua Mao, Valerie McPherson, Sue C. Kaste, Wayne L. Furman, Jianrong Wu, Sara M. Federico, Robert A. Kaufman, Alberto S. Pappo, Alison Young, Samuel L. Brady
Publikováno v:
Pediatric Blood & Cancer. 62:976-981
Background Standardization of imaging obtained in children with neuroblastoma is not well established. This study examines chest CT in pediatric patients with high-risk neuroblastoma. Procedure Medical records and imaging from 88 patients with high-r
Autor:
C. Patrick Reynolds, Malcolm A. Smith, Hernan Carol, Jianrong Wu, Raushan T. Kurmasheva, Oliver A. Hampton, Peter J. Houghton, Min H. Kang, E. Anders Kolb, David A. Wheeler, Richard B. Lock, Stephen T. Keir, Richard Gorlick, John M. Maris
Publikováno v:
Pediatric Blood & Cancer. 62:91-98
Background BMN 673 is a potent inhibitor of poly-ADP ribose polymerase (PARP) that is in clinical testing with a primary focus on BRCA-mutated cancers. BMN 673 is active both through inhibiting PARP catalytic activity and by tightly trapping PARP to
Autor:
Ewelina Mamcarz, Wayne L. Furman, Sara M. Federico, Jianrong Wu, William E. Janssen, Aimee C Talleur, Wing Leung, David Shook, Brandon M. Triplett
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 23(11)
The treatment of pediatric high-risk neuroblastoma is intensive and multimodal. Despite the introduction of immunotherapy for minimal residual disease, survival rates remain suboptimal and new therapies are needed. As part of a phase 2 trial, we are
Autor:
Arlene Naranjo, Maged Zeineldin, Jongyre Jeon, Jianrong Wu, Shenghua Mao, Michael D. Hogarty, Yanling Liu, Alberto S. Pappo, Lyra Griffith, Sara M. Federico, John Easton, Michael A. Dyer, Xiang Chen
Publikováno v:
Cancer Research. 78:PR11-PR11
Neuroblastoma is a clinically heterogeneous tumor responsible for 15% of cancer-related deaths in children. Older age at diagnosis and MYCN amplification are associated with poor prognosis in neuroblastoma. Previously, sequencing stage 4 neuroblastom