Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Larisa V, Gubareva"'
Autor:
Teena Mohan, Larisa V. Gubareva
Publikováno v:
Cold Spring Harbor perspectives in medicine. 12(1)
The neuraminidase (NA) of influenza A and B viruses plays a distinct role in viral replication and has a highly conserved catalytic site. Numerous sialic (neuraminic) acid analogs that competitively bind to the NA active site and potently inhibit enz
Autor:
Krista Kniss, Juan A. De La Cruz, Anton Chesnokov, Larisa V. Gubareva, Angiezel Merced-Morales, Jennifer Laplante, Kirsten St. George, David E. Wentworth, Rebecca Kondor, Teena Mohan, Ha T. Nguyen, Vasiliy P. Mishin, Patricia A. Blevins
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 7, Pp 1953-1957 (2021)
Emerging Infectious Diseases
Emerging Infectious Diseases
Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from
Autor:
Mira C, Patel, Daniel, Flanigan, Chenchen, Feng, Anton, Chesnokov, Ha T, Nguyen, Anwar Abd, Elal, John, Steel, Rebecca J, Kondor, David E, Wentworth, Larisa V, Gubareva, Vasiliy P, Mishin
Publikováno v:
Antiviral Research. 208:105457
Year-round virological characterization of circulating epidemic influenza viruses is conducted worldwide to detect the emergence of viruses that may escape pre-existing immunity or acquire resistance to antivirals. High throughput phenotypic assays a
Autor:
Elena A. Govorkova, Emi Takashita, Rod S. Daniels, Seiichiro Fujisaki, Lance D. Presser, Mira C. Patel, Weijuan Huang, Angie Lackenby, Ha T. Nguyen, Dmitriy Pereyaslov, Aine Rattigan, Sook Kwan Brown, Magdi Samaan, Kanta Subbarao, Sun Wong, Dayan Wang, Richard J. Webby, Hui-Ling Yen, Wenqing Zhang, Adam Meijer, Larisa V. Gubareva
Publikováno v:
Antiviral research. 200
Global analysis of the susceptibility of influenza viruses to neuraminidase (NA) inhibitors (NAIs) and the polymerase acidic (PA) inhibitor (PAI) baloxavir was conducted by five World Health Organization Collaborating Centres for Reference and Resear
Autor:
Vicki Gregory, Dmitriy Pereyaslov, Wenqing Zhang, Rod S. Daniels, Weiijuan Huang, Merryn Roe, Magdi Samaan, Ha T. Nguyen, Adam Meijer, Emi Takashita, Aeron C. Hurt, Seiichiro Fujisaki, Herman Tse, Angie Lackenby, Hui-Ling Yen, Dayan Wang, Kanta Subbarao, Larisa V. Gubareva
Publikováno v:
Antiviral research. 175
The global analysis of neuraminidase inhibitor (NAI) susceptibility of influenza viruses has been conducted since the 2012-13 period. In 2018 a novel cap-dependent endonuclease inhibitor, baloxavir, that targets polymerase acidic subunit (PA) was app
Autor:
Vicki Gregory, Sook-Kwan Leang, Dmitriy Pereyaslov, Janice Lo, Angie Lackenby, Rod S. Daniels, Alicia M. Fry, Sebastian Maurer-Stroh, Dayan Wang, Larisa V. Gubareva, Adam Meijer, Terry G. Besselaar, Takato Odagiri, Raphael T.C. Lee, Wenqing Zhang, Weijuan Huang, Emi Takashita, Aeron C. Hurt, Lori Lollis
Publikováno v:
Antiviral Research
A total of 13672 viruses, collected by World Health Organization recognised National Influenza Centres between May 2016 and May 2017, were assessed for neuraminidase inhibitor susceptibility by four WHO Collaborating Centres for Reference and Researc
Autor:
Michael G. Ison, Frederick G. Hayden, Emi Takashita, Elena A. Govorkova, Jennifer L. McKimm-Breschkin, Alan J. Hay, Larisa V. Gubareva
Publikováno v:
Antiviral Res
It is more than 20 years since the neuraminidase inhibitors, oseltamivir and zanamivir were approved for the treatment and prevention of influenza. Guidelines for global surveillance and methods for evaluating resistance were established initially by
Autor:
James Stevens, Zhu Guo, Hua Yang, Tatiana Baranovich, Katrina Sleeman, Charles T. Davis, Erin Hodges, Larisa V. Gubareva
Publikováno v:
J Infect Dis
BACKGROUND. Neuraminidase (NA) inhibitors are the recommended antiviral medications for influenza treatment. However, their therapeutic efficacy can be compromised by NA changes that emerge naturally and/or following antiviral treatment. Knowledge of
Autor:
Vasiliy P. Mishin, Ha Thuy Nguyen, Phengta Vongphrachanh, Viengphone Khanthamaly, Thongchanh Sisouk, Rebecca Garten, Khampheng Chomlasack, Tatiana Baranovich, John R. Barnes, James Stevens, Larisa V. Gubareva, David E. Wentworth, Henju Marjuki, Pakapak Ketmayoon
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 4, Pp 686-690 (2017)
Emerging Infectious Diseases
Emerging Infectious Diseases
In February 2016, three influenza B/Victoria/2/87 lineage viruses exhibiting 4- to 158-fold reduced inhibition by neuraminidase inhibitors were detected in Laos. These viruses had an H134N substitution in the neuraminidase and replicated efficiently
Autor:
Erin Hodges, Larisa V. Gubareva, Vasiliy P. Mishin, David E. Wentworth, Zhu Guo, Ha T. Nguyen, Eric Fallows, Charles T. Davis, James Stevens, De la Cruz J
Publikováno v:
Influenza and Other Respiratory Viruses
Mutations in the influenza virus neuraminidase (NA) that cause reduced susceptibility to the NA inhibitor (NAI) oseltamivir may occur naturally or following antiviral treatment. Currently, detection uses either a traditional NA inhibition assay or ge