Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeffrey E. DeClue"'
Publikováno v:
Journal of Neuroscience Research. 49:236-247
Schwann cell proliferation is stimulated by contact with neurons or exposure to growth factor ligands for tyrosine kinase receptors, effects of which are potentiated by cAMP. Here we show that treatment of rat Schwann cells with recombinant human gli
Autor:
Nancy Ratner, Yuan Huang, Tilat A. Rizvi, Jason Bowersock, John Vitullo, Shyra J. Miller, Linda M. Parysek, Gunnar Johansson, Kristine S. Vogel, Hongzhen Li, Jeffrey E. DeClue, Amer Sidani
Publikováno v:
Molecular and cellular biology. 23(6)
Loss of axonal contact characterizes Schwann cells in benign and malignant peripheral nerve sheath tumors (MPNST) from neurofibromatosis type 1 (NF1) patients. Tumor Schwann cells demonstrate NF1 mutations, elevated Ras activity, and aberrant epiderm
Autor:
Shyra J. Miller, Tilat A. Rizvi, Gabrielle deCourten-Myers, Jianqiang Wu, Nancy Ratner, Benjamin C. Ling, Kelly R. Monk, Kristine S. Vogel, Jeffrey E. DeClue, Rania Shamekh
Publikováno v:
Cancer cell. 7(1)
Benign neurofibromas and malignant peripheral nerve sheath tumors are serious complications of neurofibromatosis type 1. The epidermal growth factor receptor is not expressed by normal Schwann cells, yet is overexpressed in subpopulations of Nf1 muta
Autor:
David H. Gutmann, John C. Maize, Richard L. Heideman, Ralf Wienecke, Jeffrey E. DeClue, Abhijit Guha
Publikováno v:
Annals of neurology. 42(2)
Individuals affected with tuberous sclerosis complex (TSC) develop several benign and malignant tumors at increased frequency, including astrocytomas. Tuberin, the protein product of the tuberous sclerosis complex-2 (TSC2) tumor suppressor gene, has
Autor:
Jeffrey E. DeClue, Harry V. Vinters, Michael J. De Rosa, Vadims Poukens, Ralf Wienecke, Samuel H. Pepkowitz, Christopher Kerfoot, Sung Hye Park
Publikováno v:
Acta neuropathologica. 94(2)
We report an autopsy case of tuberous sclerosis complex (TSC) in a 20-week gestational age female fetus. The brain showed lesions suggestive of early cortical tubers and subependymal hamartomatous nodules. The large cells within these nodular cluster