Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jane A. Cox"'
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148726 (2016)
PLoS ONE
PLoS ONE
Peripheral glia are known to have a critical role in the initial response to axon damage and degeneration. However, little is known about the cellular responses of non-myelinating glia to nerve injury. In this study, we analyzed the transcriptomes of
Publikováno v:
Neuroscience. 138(2)
The two paralogous P2X receptor subunit genes p2rx3.1 and p2rx3.2 are selectively expressed in overlapping, but unique, patterns of sensory neurons in the developing zebrafish. We constructed a series of transgenes derived from both genes using the r
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 234(3)
We present the cloning of 10 N-methyl-D-aspartate (NMDA) receptor subunits from the zebrafish. These subunits fall into five subtypes, each containing two paralogous genes. Thus, we report two NMDAR1 genes (NR1.1 and NR1.2), and eight NMDAR2 genes, d
Publikováno v:
Neuroscience. 121(4)
P2X receptors are non-selective cation channels gated by extracellular ATP and are encoded by a family of seven subunit genes in mammals. These receptors exhibit high permeabilities to calcium and in the mammalian nervous system they have been linked
Publikováno v:
Neuron. 4(6)
Using neurotoxicity and inositol phosphate release as criteria for receptor expression, we report the differential expression of excitatory amino acid receptor subtypes in cerebellar granule cells grown in serum-free media containing either high (25
Publikováno v:
Developmental Biology. (2):305-317
The formation of branchiomeric nerves (cranial nerves V, VII, IX and X) from their sensory, motor and glial components is poorly understood. The current model for cranial nerve formation is based on the Vth nerve, in which sensory afferents are forme
Publikováno v:
Annals of the New York Academy of Sciences. 568
Our results demonstrated that the neurotoxicity of glutamate and closely related agonists was mediated by the NMDA receptor in rat cerebellar granule cells. Evidence was presented to support our hypothesis that the pivotal event in the transition of
Publikováno v:
Brain research. 499(2)
l -Glutamate neurotoxicity at the N-methyl- d -aspartate (NMDA) receptor was characterized in cultured cerebellar granule cells. When deprived of glucose for 40 min, these cells were killed by 20–60 μM l -glutamate. However, the neurons were resis