Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christoph Kellendonk"'
Publikováno v:
Behav Neurosci
Ventral striatal dopamine is thought to be important for associative learning. Dopamine exerts its role via activation of dopamine D1 and D2 receptors in the ventral striatum. Upregulation of dopamine D2R in ventral striatopallidal neurons impairs in
Autor:
Chia-Yuan Chang, Daniel C. Lowes, Alan J. Park, Joshua A. Gordon, Atheir I. Abbas, Christoph Kellendonk, Alexander Z. Harris, Kelly M. Martyniuk, Joseph A. Gogos
Publikováno v:
Nature. 591:615-619
The ability to rapidly adapt to novel situations is essential for survival, and this flexibility is impaired in many neuropsychiatric disorders1. Thus, understanding whether and how novelty prepares, or primes, brain circuitry to facilitate cognitive
Autor:
T. H. C. Cheung, Jozsef Meszaros, Un Jung Kang, Dalibor Sames, Christoph Kellendonk, Maya M Erler, David Sulzer
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Dopamine neurotransmission is suspected to play important physiological roles in multiple sparsely innervated brain nuclei, but there has not been a means to measure synaptic dopamine release in such regions. The globus pallidus externa (GPe) is a ma
Autor:
Ryan Sahn, Scott S. Bolkan, Christoph Kellendonk, Nancy Padilla-Coreano, Alan S. Brown, Neil L. Harrison, LouJin Song, Sarah Canetta, Joshua A. Gordon
Publikováno v:
Molecular psychiatry
Abnormalities in prefrontal gamma aminobutyric acid (GABA)ergic transmission, particularly in fast-spiking interneurons that express parvalbumin (PV), are hypothesized to contribute to the pathophysiology of multiple psychiatric disorders, including
Autor:
Rachel Mikofsky, Sofiya Hupalo, Sarah Canetta, Nancy Padilla-Coreano, Emily Alway, Richard Warren, Johannes Passecker, Mitchell P. Morton, David A. Kupferschmidt, Maxym Myroshnychenko, Joshua A. Gordon, Alvaro L. Garcia-Garcia, Christoph Kellendonk, Eric Teboul, Dakota R. Blackman, Kay M. Tye
Publikováno v:
Neuron
Long-range synchronization of neural oscillations correlates with distinct behaviors, yet its causal role remains unproven. In mice, tests of anxiety-like avoidance behavior evoke increases in theta-frequency (~8 Hz) oscillatory synchrony between the
Autor:
Mitchell P. Morton, Britt Henoch, Joshua A. Gordon, Alan J. Park, Alexander Z. Harris, Christoph Kellendonk, Scott S. Bolkan, Atheir I. Abbas, Marina J.M. Sundiang
Publikováno v:
Neuron. 100(4)
Summary Decreased hippocampal-prefrontal synchrony may mediate cognitive deficits in schizophrenia, but it remains unclear which cells orchestrate this long-range synchrony. Parvalbumin (PV)- and somatostatin (SOM)-expressing interneurons show histol
Autor:
Atheir I. Abbas, Joshua A. Gordon, Caroline Rauffenbart, Scott S. Bolkan, Christoph Kellendonk, Joseph M. Stujenske, Sébastien Parnaudeau, Alexander Z. Harris, Timothy Spellman
Publikováno v:
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2017, advance online publication, pp.987-996. ⟨10.1038/nn.4568⟩
Nature neuroscience
Nature Neuroscience, 2017, 20, pp.987-996. ⟨10.1038/nn.4568⟩
Nature Neuroscience, Nature Publishing Group, 2017, 20 (7), pp.987-996. ⟨10.1038/nn.4568⟩
Nature Neuroscience, Nature Publishing Group, 2017, advance online publication, pp.987-996. ⟨10.1038/nn.4568⟩
Nature neuroscience
Nature Neuroscience, 2017, 20, pp.987-996. ⟨10.1038/nn.4568⟩
Nature Neuroscience, Nature Publishing Group, 2017, 20 (7), pp.987-996. ⟨10.1038/nn.4568⟩
International audience; The mediodorsal thalamus (MD) shares reciprocal connectivity with the prefrontal cortex (PFC), and decreased MD–PFC connectivity is observed in schizophrenia patients. Patients also display cognitive deficits including impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf6994122690578426be679e74a1627
https://hal.archives-ouvertes.fr/hal-01544138
https://hal.archives-ouvertes.fr/hal-01544138
Autor:
Alex Dranovsky, Bruno P. Guiard, Alain M. Gardier, Sarah E. Canetta, Qingyuan Meng, E. David Leonardo, Alvaro L. Garcia-Garcia, Christoph Kellendonk
Publikováno v:
Cell Reports, Vol 18, Iss 5, Pp 1144-1156 (2017)
Lifelong homeostatic setpoints for mood-related behaviors emerge during adolescence. Serotonin (5-HT) plays an important role in refining the formation of brain circuits during sensitive developmental periods. In rodents, the role of 5-HT1A receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70598c4131183faa5c7ad9cf2934dd3f
https://europepmc.org/articles/PMC5325088/
https://europepmc.org/articles/PMC5325088/
Autor:
Paul E. M. Phillips, Gaël Malleret, Vanessa Winiger, Scott Ng-Evans, Julia Morud, Mary Elizabeth Bach, H. Jonathan Polan, Eleanor H. Simpson, Dominik Biezonski, Christoph Kellendonk, Judy P. Zhu, Eric R. Kandel
Publikováno v:
Learning & Memory. 21:205-214
A common genetic polymorphism that results in increased activity of the dopamine regulating enzyme COMT (the COMT Val158 allele) has been found to associate with poorer cognitive performance and increased susceptibility to develop psychiatric disorde
Autor:
Maxime Cazorla, Susanne E. Ahmari, Holly Moore, Muhammad Omar Chohan, Christoph Kellendonk, Mariya Shegda, Fernanda Delmondes de Carvalho, Nao Chuhma, Stephen Rayport
Publikováno v:
Neuron
Neuron, Elsevier, 2014, 81 (1), pp.153-64. ⟨10.1016/j.neuron.2013.10.041⟩
Neuron, Elsevier, 2014, 81 (1), pp.153-64. ⟨10.1016/j.neuron.2013.10.041⟩
International audience; Structural plasticity in the adult brain is essential for adaptive behavior. We have found a remarkable anatomical plasticity in the basal ganglia of adult mice that is regulated by dopamine D2 receptors (D2Rs). By modulating