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pro vyhledávání: '"David Spiegel"'
Autor:
David Spiegel, Jeanene Fogli, Jeffrey J. Connaire, Christopher G. Rowan, Nina Oestreicher, Csaba P. Kovesdy, Ansgar Conrad, Wolfgang C. Winkelmayer
Publikováno v:
Kidney International Reports
Kidney International Reports, Vol 4, Iss 2, Pp 301-309 (2019)
Kidney International Reports, Vol 4, Iss 2, Pp 301-309 (2019)
Introduction: Patiromer is a potassium (K+) binding polymer indicated for treating hyperkalemia. Among patients receiving chronic hemodialysis (HD), this study aimed to identify patient characteristics associated with patiromer initiation, describe p
Autor:
David Spiegel, Csaba P. Kovesdy, Charles Du Mond, Steven M. Brunelli, Wolfgang C. Winkelmayer, Nina Oestreicher
Publikováno v:
Nephrology Dialysis Transplantation
Background A high serum-to-dialysate potassium (K+) gradient at the start of dialysis leads to rapid lowering of serum K+ and may confer a greater risk of adverse events. Here, we examined the near-term association of K+ gradient with clinical outcom
Publikováno v:
American Journal of Kidney Diseases. 70:21-29
Hyperkalemia is common among hemodialysis patients and is associated with morbidity and mortality. The long interdialytic interval is likewise associated with adverse outcomes. However, the interplay among serum potassium, dialysis cycle phase, and c
Autor:
David Spiegel, Pablo E. Pergola, David A. Bushinsky, Suzette Warren, Jinwei Yuan, Jeanene Fogli
BACKGROUND AND OBJECTIVES: Patiromer is a sodium-free, nonabsorbed, potassium-binding polymer that uses calcium as the counter-exchange ion and is approved for treatment of hyperkalemia. The 4-week TOURMALINE study in patients with hyperkalemia previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c2c8fa4849a3cd0fb0de5ca70d1ed9
https://europepmc.org/articles/PMC6364526/
https://europepmc.org/articles/PMC6364526/
Background: Patiromer is a sodium-free, nonabsorbed, potassium binder approved for treatment of hyperkalemia. This open-label study compares the efficacy and safety of patiromer administered without food versus with food. Methods: Adults with hyperka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ba963adb239706a657e4eb8f1a273e
https://europepmc.org/articles/PMC5804834/
https://europepmc.org/articles/PMC5804834/
Autor:
Matthew R. Weir, Jeanene Fogli, Coleman Gross, Charles Du Mond, Kathleen M. Hill Gallant, Wade W. Benton, Geoffrey A. Block, David Spiegel, Bertram Pitt, David A. Bushinsky
Publikováno v:
Clinical journal of the American Society of Nephrology : CJASN. 11(10)
Background and objectives Patiromer is a nonabsorbed potassium-binding polymer that uses calcium as the counterexchange ion. The calcium released with potassium binding has the potential to be absorbed or bind phosphate. Because binding is not specif
Autor:
David Spiegel, Kate Brady
Publikováno v:
Kidney international
Calcium balance in chronic kidney disease is poorly understood as calcium deficiency is a stimulus for secondary hyperparathyroidism and consequent bone loss while calcium excess promotes extraosseous calcifications. To help resolve this, we evaluate
Autor:
David Spiegel
Publikováno v:
Advances in Chronic Kidney Disease. 19:166-170
Appropriate dialysate composition is critical for effective and safe hemodialysis. Unfortunately, there are few randomized trials to guide practice, and although solute clearance is well understood, there is a limited understanding of balance in dial
Autor:
David Spiegel
Publikováno v:
Blood Purification. 31:172-176
Background: Magnesium ion is critical for life and is integrally involved in cellular function and a key component of normal bone mineral. In health, the kidneys, gastrointestinal tract and bone are responsible for maintaining serum magnesium concent
Autor:
Alain Romero, Dinesh Chatoth, Ann Mooney, Kathryn Anastassopoulos, Tyler Knight, Viatcheslav Rakov, Carly Van Zandt, David Spiegel, Sam Colman, Peter M Wahl
Publikováno v:
Nephrology Dialysis Transplantation. 33:i218-i218