Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Stephanie Ting"'
Autor:
Sudeep, Banerjee, Hyunho, Yoon, Stephanie, Ting, Chih-Min, Tang, Mayra, Yebra, Alexander T, Wenzel, Huwate, Yeerna, Jill P, Mesirov, Robert J, Wechsler-Reya, Pablo, Tamayo, Jason K, Sicklick
Publikováno v:
Mol Cancer Ther
Gastrointestinal stromal tumor (GIST) is commonly driven by oncogenic KIT mutations that are effectively targeted by imatinib, a tyrosine kinase inhibitor (TKI). However, IM does not cure GIST and adjuvant therapy only delays recurrence in high-risk
Autor:
Jonathan Liang, Andrew J. Aguirre, David A. Barbie, Jong Wook Kim, Huwate Yeerna, Karina Meneses-Cime, Pablo Tamayo, Emily Damato, Mahmoud Ghandi, Jason Park, Kate Medetgul-Ernar, Chen-Hsiang Yeang, Michelle Stewart, Barbara A. Weir, Aviad Tsherniak, Jill P. Mesirov, David Thomas, Gabriella Alexe, William C. Hahn, Eliezer M. Van Allen, Taylor B. Cavazos, Paul A. Clemons, Russell W. Jenkins, Jesse S. Boehm, John G. Doench, Ofir Cohen, Stephanie Ting, Shunsuke Kitajima, Levi A. Garraway, Arthur Liberzon, Omar O. Abudayyeh, David J. Konieczkowski, John H McDermott, Clarence K. Mah, Aravind Subramanian, Francisca Vazquez
Publikováno v:
Cell systems, vol 5, iss 2
The systematic sequencing of the cancer genome has led to the identification of numerous genetic alterations in cancer. However, a deeper understanding of the functional consequences of thesealterations is necessary to guide appropriatetherapeutic st