Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Markus Riester"'
Publikováno v:
JCO Clinical Cancer Informatics
PURPOSE Allele-specific copy number alteration (CNA) analysis is essential to study the functional impact of single-nucleotide variants (SNVs) and the process of tumorigenesis. However, controversy over whether it can be performed with sufficient acc
Autor:
Aedín C. Culhane, Levi Waldron, Vincent J. Carey, Rimsha Azhar, Arvind Singh Mer, Kasper D. Hansen, Phil Chapman, Angela Re, Tiffany Chan, Sean Davis, Carmen Rodríguez, Martin Morgan, Lucas Schiffer, Marcel Ramos, Azfar Basunia, Hanish Kodali, David Gomez-Cabrero, Marie Stephie Louis, Benjamin Haibe-Kains, Markus Riester
Multiomics experiments are increasingly commonplace in biomedical research and add layers of complexity to experimental design, data integration, and analysis. R and Bioconductor provide a generic framework for statistical analysis and visualization,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e30862f56ff06721647c1c42206b322
https://europepmc.org/articles/PMC5679241/
https://europepmc.org/articles/PMC5679241/
Autor:
Rachel S. Park, Enrique Gallardo, André P. Fay, Joaquim Bellmunt, Jonathan E. Rosenberg, Lillian Werner, Massimo Loda, Markus Riester, Richard Martin Bambury, Elizabeth A. Guancial, David M. Berman, Silvia de Muga, Toni K. Choueiri, Stephanie A. Mullane, Justine A. Barletta, Aristotle Bamias, Edward C. Stack, Shamini Selvarajah, Federico Rojo, Marta Salido
Publikováno v:
Cancer Medicine
Repositório Institucional PUCRS
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
Repositório Institucional PUCRS
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
We evaluated primary tumors from two cohorts, Spain (N = 111) and Greece (N = 102), for patients who were treated with platinum-based chemotherapy. Patients were tested for HER2 status (IHC score of 3+ or FISH ratio of ≥2.2) by immunohistochemistry
Autor:
Robert J. Downey, Ahmet Zehir, Markus Riester, Hua-Jun Wu, Andre L. Moreira, Franziska Michor, Mithat Gonen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 3, p e0173589 (2017)
PLoS ONE, Vol 12, Iss 3, p e0173589 (2017)
The degree of histologic cellular differentiation of a cancer has been associated with prognosis but is subjectively assessed. We hypothesized that information about tumor differentiation of individual cancers could be derived objectively from cancer
Autor:
Tatsuya Ozawa, Karim Helmy, Jason T. Huse, Franziska Michor, Massimo Squatrito, Markus Riester, Eric C. Holland, Nikki Charles, Yu-Kang Cheng
Publikováno v:
Cancer Cell. 26:288-300
SummaryTo understand the relationships between the non-GCIMP glioblastoma (GBM) subgroups, we performed mathematical modeling to predict the temporal sequence of driver events during tumorigenesis. The most common order of evolutionary events is 1) c
Publikováno v:
Journal of the National Cancer Institute. 108:djw146
Whole-genome analysis of cancer specimens is commonplace, and investigators frequently share or re-use specimens in later studies. Duplicate expression profiles in public databases will impact re-analysis if left undetected, a so-called “doppelgän
Human tumors result from an evolutionary process operating on somatic cells within tissues, whereby natural selection operates on the phenotypic variability generated by the accumulation of genetic, genomic and epigenetic alterations. This somatic ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cdbd274b9e9a30c7eaa6d72257a1ae
https://europepmc.org/articles/PMC3711268/
https://europepmc.org/articles/PMC3711268/
Autor:
Robert J. Downey, Markus Riester, Franziska Michor, Samuel Singer, Camille Stephan-Otto Attolini
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 6, Iss 5, p e1000777 (2010)
PLoS Computational Biology, Vol 6, Iss 5, p e1000777 (2010)
Histopathological classification of human tumors relies in part on the degree of differentiation of the tumor sample. To date, there is no objective systematic method to categorize tumor subtypes by maturation. In this paper, we introduce a novel com
Autor:
David Chen, Fabrice Andre, Tanya Taran, Luca Gianni, Ruth O'Regan, Wei He, Howard A. Burris, Douglas Robinson, Claudine Isaacs, Sara A. Hurvitz, Masakazu Toi, Guy Jerusalem, Ling-Ming Tseng, Sharon Wilks, Markus Riester, Dennis J. Slamon
Publikováno v:
Journal of Clinical Oncology. 33:512-512
512 Background: Two phase 3 trials BOLERO-1 and BOLERO-3 evaluated the addition of everolimus (EVE) to trastuzumab (TRAS) + chemotherapy in HER2+ advanced breast cancer (ABC). In BOL-3, heavily pre...