Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kathy Mulgrew"'
Autor:
Chih-Hang Anthony Tang, Kristin C. Hicks, Sergei I. Grivennikov, Chih-Chi Andrew Hu, Dmitry I. Gabrilovich, E. John Wherry, Fernanda Pilataxi, Shino Hanabuchi, Corinne Cayatte, Gozde Kar, Kathy Mulgrew, Aimee Landry, Evgenii N. Tcyganov, Brian Dougherty, Ayumi Hashimoto, Yulia Nefedova, David A Campbell, Susana Hayes, Wei Guo, Tim Slidel, Mohammed Alkhatim A. Ali, Jean Christophe Beltra
Publikováno v:
J Clin Invest
Myeloid-derived suppressor cells (MDSCs) are major negative regulators of immune responses in cancer and chronic infections. It remains unclear if regulation of MDSC activity in different conditions is controlled by similar mechanisms. We compared MD
Autor:
Kathy Mulgrew, JoAnn Suzich, Hong Ji, Scott A. Hammond, Elizabeth J. Kelly, Ronald Herbst, Nicholas M. Durham, Noel R. Monks, Kelly McGlinchey
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 25(8)
Vesicular stomatitis virus encoding the IFNβ transgene (VSV-IFNβ) is a mediator of potent oncolytic activity and is undergoing clinical evaluation for the treatment of solid tumors. Emerging preclinical and clinical data suggest treatment of tumors
Autor:
Xiao Tao Yao, Bill Walsh, Michael S. Kinch, Krista Kinneer, Kathy Mulgrew, David A. Tice, Changshou Gao, Beth K. Ward, Peter A. Kiener, Steve Coats, Su Yau Mao, Melissa Damschroder
Publikováno v:
Molecular Cancer Therapeutics. 5:3122-3129
The humanized monoclonal antibody Abegrin™, currently in phase II trials for treatment of solid tumors, specifically recognizes the integrin αvβ3. Due to its high expression on mature osteoclasts, angiogenic endothelial cells, and tumor cells, in
Autor:
Ralf Lutterbuese, Patrick A. Baeuerle, Petra Lutterbuese, Kathy Mulgrew, Peter Kufer, Peter A. Kiener, Bernd Schlereth, Evelyne Schaller, Scott A. Hammond, Michael Oberst, Doris Rau, Tobias Raum, Petra Meier, Susanne Mangold, Roman Kischel
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 32(4)
Carcinoembryonic antigen (CEA, CD66e) is a well-characterized tumor-associated antigen that is frequently overexpressed in tumors. Phospholipases release CEA from tumor cells resulting in high circulating serum levels of soluble CEA (sCEA) that has b
Publikováno v:
Gene therapy. 10(16)
Adenoviral vectors infect cells through the binding of capsid proteins to cell-surface receptors. The ubiquitous expression of adenoviral receptors in human tissues represents an obstacle toward the development of systemically deliverable vectors for