Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mei Zhai"'
Autor:
Kun Wang, Mei Zhai, Man Wang, Yan Huang, Tao Wang, Xinzhe Chen, Chan Shan, Peipei Shan, Jing-Yi Xie, Kai Wang, Xiang-Qian Gao, Cuiyun Liu, Sheng Xu, Jing Liu, De-Yu Zhang, Zhou Luyu, Murugavel Ponnusamy
Publikováno v:
Theranostics
Mitochondrial dysfunction is involved in the pathogenesis of various cardiovascular disorders. Although mitochondrial dynamics, including changes in mitochondrial fission and fusion, have been implicated in the development of cardiac hypertrophy, the
Autor:
Kun Wang, Yuhui Zhang, Qi Wang, Jian Zhang, Peifeng Li, Cuiyun Liu, Kaowen Yan, Chan Shan, Rui-Bei Li, Yan-Hui Zhang, Yanhan Dong, Sheng Xu, Fei Liu, Li-Li Qian, Fang Liu, Zhou Luyu, Mei Zhai, Man Wang, Murugavel Ponnusamy
Publikováno v:
Circulation. 139:2668-2684
Background: The adult mammalian cardiomyocytes lose their proliferative capacity, which is responsible for cardiac dysfunction and heart failure following injury. The molecular mechanisms underlying the attenuation of adult cardiomyocyte proliferatio
Autor:
Mei Zhai, Kun Wang, Yuhui Zhang, Kaowen Yan, Tao Wang, Yunhong Wang, Qi Wang, Rongcheng Zhang, Jian Zhang, Tao An, Yan Huang, Jing Liu
Publikováno v:
Cell Death and Disease, Vol 10, Iss 7, Pp 1-16 (2019)
Cell Death & Disease
Cell Death & Disease
Mitochondrial dysfunction plays a major role in the pathogenesis of cardiovascular diseases. MicroRNAs (miRNAs) are small RNAs that act as negative regulators of gene expression, but how miRNAs affect mitochondrial function in the heart is unclear. U
Autor:
Xiang-Qian, Gao, Yu-Hui, Zhang, Fang, Liu, Murugavel, Ponnusamy, Xue-Mei, Zhao, Lu-Yu, Zhou, Mei, Zhai, Cui-Yun, Liu, Xin-Min, Li, Man, Wang, Chan, Shan, Pei-Pei, Shan, Yin, Wang, Yan-Han, Dong, Li-Li, Qian, Tao, Yu, Jie, Ju, Tao, Wang, Kai, Wang, Xin-Zhe, Chen, Yun-Hong, Wang, Jian, Zhang, Pei-Feng, Li, Kun, Wang
Publikováno v:
Nature cell biology. 22(11)
PIWI-interacting RNAs (piRNAs) are abundantly expressed during cardiac hypertrophy. However, their functions and molecular mechanisms remain unknown. Here, we identified a cardiac-hypertrophy-associated piRNA (CHAPIR) that promotes pathological hyper
Autor:
Tao An, Murugavel Ponnusamy, Chan Shan, Yanhan Dong, Yan Huang, Cuiyun Liu, Kaowen Yan, Mei Zhai, Rui-Bei Li, Kun Wang, Rongcheng Zhang, Yuhui Zhang, Jian Zhang, Yan-Hui Zhang, Sheng Xu, Zhou Luyu, Qi Wang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
Increasing evidence suggests that long noncoding RNAs (lncRNAs) play crucial roles in various biological processes. However, little is known about the effects of lncRNAs on autophagy. Here we report that a lncRNA, termed cardiac autophagy inhibitory