Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jessica S. Crystal"'
Autor:
Harshini Chinnasamy, Todd D. Prickett, Li Jia, Paul F. Robbins, Isaac R. Kriley, Yasmine Assadipour, Steven A. Rosenberg, Steven A. Feldman, Stephanie L. Goff, Jared J. Gartner, Nikolaos Zacharakis, Jessica S. Crystal, John R. Wunderlich, Yong-Chen Lu, Robert Somerville, Mary A. Black, Lily Lu, Hui Xu, Zhili Zheng
Publikováno v:
Clinical Cancer Research. 23:4347-4353
Purpose: The administration of autologous tumor-infiltrating lymphocytes (TILs) can mediate durable tumor regressions in patients with melanoma likely based on the recognition of immunogenic somatic mutations expressed by the cancer. There are limite
Autor:
Maria R. Parkhurst, Anna Pasetto, Alena Gros, Jessica S. Crystal, Steven A. Rosenberg, Todd D. Prickett, Paul F. Robbins
Publikováno v:
Clinical Cancer Research. 23:2491-2505
Purpose: The adoptive transfer of lymphocytes genetically modified to express tumor reactive T-cell receptors (TCR) can mediate tumor regression. Some tumor-infiltrating lymphocytes (TIL) recognize somatic mutations expressed only in the patient's tu
Autor:
Jared J. Gartner, Alena Gros, Maria R. Parkhurst, Harlan Robins, Paul F. Robbins, Daniel C. Douek, Rodrigo Matus-Nicodemos, Steven A. Rosenberg, Katarzyna Trebska-McGowan, Todd D. Prickett, Jessica S. Crystal, Anna Pasetto, Bryan Howie, Drew C. Deniger
Publikováno v:
Cancer Immunology Research. 4:734-743
Adoptive transfer of T cells with engineered T-cell receptor (TCR) genes that target tumor-specific antigens can mediate cancer regression. Accumulating evidence suggests that the clinical success of many immunotherapies is mediated by T cells target
Autor:
John R. Wunderlich, Paul F. Robbins, Anna Pasetto, Li Jia, Mona El-Gamil, Gal Cafri, Maria R. Parkhurst, Eric Tran, Yong F. Li, Lien T. Ngo, Winifred Lo, Robert Somerville, Mojgan Ahmadzadeh, Jessica S. Crystal, Todd D. Prickett, Gabriel Ivey, Satyajit Ray, Frank J. Lowery, Rami Yossef, Abraham Sachs, Steven A. Rosenberg, Almin Lalani, Scott Kivitz, Eric M. Groh, Drew C. Deniger, Parisa Malekzadeh, Stephanie L. Goff, Jared J. Gartner
Publikováno v:
Cancer discovery. 9(8)
Immunotherapies can mediate regression of human tumors with high mutation rates, but responses are rarely observed in patients with common epithelial cancers. This raises the question of whether patients with these common cancers harbor T lymphocytes
Autor:
Kasia Trebska-Mcgowan, Steven A. Rosenberg, Chen Ankri, Jared J. Gartner, Miryam Horovitz-Fried, Yong F. Li, Cyrille J. Cohen, Maria R. Parkhurst, Mona El-Gamil, Valery Bliskovsky, Todd D. Prickett, Paul F. Robbins, Katerina Shamalov, Jessica S. Crystal
Publikováno v:
Journal of Clinical Investigation. 125:3981-3991
Adoptively transferred tumor-infiltrating T lymphocytes (TILs) that mediate complete regression of metastatic melanoma have been shown to recognize mutated epitopes expressed by autologous tumors. Here, in an attempt to develop a strategy for facilit
Autor:
Lindy Davis, Jessica S. Crystal, Steven A. Rosenberg, Yong-Chen Lu, James Chih-Hsin Yang, Paul F. Robbins, Mona El-Gamil, Colin A. Gross, Xin Yao, Yardena Samuels, Yong F. Li, Mark E. Dudley
Publikováno v:
Clinical Cancer Research. 20:3401-3410
Purpose: Cancer immunotherapy with adoptive transfer of tumor-infiltrating lymphocytes (TIL) represents an effective treatment for patients with metastatic melanoma, with the objective regressions in up to 72% of patients in three clinical trials. Ho
Autor:
Mona El-Gamil, Kasia Trebska-Mcgowan, Jessica S. Crystal, Alena Gros, Jared J. Gartner, Yong F. Li, Todd D. Prickett, Rong Wang, Maria R. Parkhurst, Paul F. Robbins, Cyrille J. Cohen, Anna Pasetto, Steven A. Rosenberg, Xin Yao
Immunotherapy treatment of patients with metastatic cancer has assumed a prominent role in the clinic. Durable complete response rates of 20% to 25% are achieved in patients with metastatic melanoma following adoptive cell transfer of T cells derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19efe2a29b55440eab521a9e872e0387
https://europepmc.org/articles/PMC4970903/
https://europepmc.org/articles/PMC4970903/
Autor:
Eric Tran, Kasia Trebska-Mcgowan, Sadia Ilyas, John R Wudnerlich, Steven A. Rosenberg, Pasetto Anna, Alena Gros, Todd D. Prickett, Jessica S. Crystal, Paul F. Robbins, James Chih-Hsin Yang, Maria R. Parkhurst, Jared J. Gartner
Publikováno v:
Journal for Immunotherapy of Cancer
Meeting abstracts T cells targeting unique somatic mutations appear to play an important role in the antitumor responses observed following T cell transfer, and isolation of mutation-specific lymphocytes and T-cell receptors has become a major obstac