Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jan B. Koenderink"'
Autor:
Wilma Kiander, Mikko Gynther, Kati-Sisko Vellonen, Madhushree Bhattacharya, Heidi Kidron, Melina M. Malinen, Seppo Auriola, Marja Hagström, Jan B. Koenderink
Publikováno v:
Pharmaceutical Research, 38, 10, pp. 1663-1675
Pharmaceutical Research, 38, 1663-1675
Pharmaceutical Research
Pharmaceutical Research, 38, 1663-1675
Pharmaceutical Research
Purpose Organic Anion Transporting Polypeptide 1B1 (OATP1B1) mediates hepatic influx and clearance of many drugs, including statins. The SLCO1B1 gene is highly polymorphic and its function-impairing variants can predispose patients to adverse effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ec5a3cafa9fa7a792eb27bf4691d5e
Autor:
Herman G.P. Swarts, Jan B. Koenderink, Karl M. Weigand, Frans G. M. Russel, Muriël Messchaert
Publikováno v:
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1842, 7, pp. 1010-6
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1842, 1010-6
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1842, 1010-6
Contains fulltext : 128411.pdf (Publisher’s version ) (Closed access) De novo mutations in ATP1A3, the gene encoding the alpha3-subunit of Na(+),K(+)-ATPase, are associated with the neurodevelopmental disorder Alternating Hemiplegia of Childhood (A
Autor:
Natalya U. Fedosova, Julia Sandrock, Poul Nissen, Karl M. Weigand, Jan B. Koenderink, Frans G. M. Russel, Mette Laursen, Anthonius H. J. Engwerda, Herman G.P. Swarts, Christian Prüfert
Publikováno v:
Weigand, K, Laursen, M, Swarts, H G P, Engwerda, A H J, Prufert, C, Sandrock, J, Nissen, P, Fedosova, N, Russel, F G M & Koenderink, J B 2014, ' Na(+),K(+)-ATPase Isoform Selectivity for Digitalis-Like Compounds Is Determined by Two Amino Acids in the First Extracellular Loop ', Chemical Research in Toxicology, vol. 27, no. 12, pp. 2082-2092 . https://doi.org/10.1021/tx500290k
Chemical Research in Toxicology, 27, 2082-92
Chemical Research in Toxicology, 27, 12, pp. 2082-92
Chemical Research in Toxicology, 27, 2082-92
Chemical Research in Toxicology, 27, 12, pp. 2082-92
Contains fulltext : 135976.pdf (Publisher’s version ) (Closed access) Digitalis-like compounds (DLCs) comprise a diverse group of molecules characterized by a cis-trans-cis ring-fused steroid core linked to a lactone. They have been used in the tre
Autor:
Herman G.P. Swarts, Karl M. Weigand, Hanka Venselaar, Frans G. M. Russel, Jan B. Koenderink, Arn M. J. M. van den Maagdenberg
Publikováno v:
BBA-Molecular Basis of Disease, 1832(12), 2173-2179
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1832, 2173-9
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1832, 12, pp. 2173-9
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1832, 2173-9
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1832, 12, pp. 2173-9
Contains fulltext : 125451.pdf (Publisher’s version ) (Closed access) Familial hemiplegic migraine (FHM) is a monogenic variant of migraine with aura. One of the three known causative genes, ATP1A2, which encodes the alpha2 isoform of Na,K-ATPase,
Autor:
Li Yan Qiu, Herman G.P. Swarts, Jan B. Koenderink, Jan Joep H.H.M. De Pont, Elisa C.M. Tonk, Peter H.G.M. Willems
Publikováno v:
Journal of Biological Chemistry, 281, 13533-9
Journal of Biological Chemistry, 281, 19, pp. 13533-9
Journal of Biological Chemistry, 281, 19, pp. 13533-9
Contains fulltext : 49286.pdf (Publisher’s version ) (Open Access) P-type ATPases of the IIC subfamily exhibit large differences in sensitivity toward ouabain. This allows a strategy in which ouabain-insensitive members of this subfamily are used a
Autor:
Gijs Schaftenaar, Herman G.P. Swarts, Peter H.G.M. Willems, Jan B. Koenderink, Elmar Krieger, Jan Joep H.H.M. De Pont, Li Yan Qiu
Publikováno v:
Journal of Biological Chemistry, 280, 32349-32355
Journal of Biological Chemistry, 280, 37, pp. 32349-32355
Journal of Biological Chemistry, 280, 37, pp. 32349-55
Journal of Biological Chemistry, 280, 32349-55
Journal of Biological Chemistry, 280, 37, pp. 32349-32355
Journal of Biological Chemistry, 280, 37, pp. 32349-55
Journal of Biological Chemistry, 280, 32349-55
Contains fulltext : 32914.pdf (Publisher’s version ) (Open Access) Contains fulltext : 189403.pdf (Publisher’s version ) (Open Access) Although cardiac glycosides have been used as drugs for more than 2 centuries and their primary target, the sod
Autor:
Giovanni Zifarelli, Ernst Bamberg, Jan B. Koenderink, Thomas Friedrich, Li Yan Qiu, Wolfgang Schwarz, Jan Joep H.H.M. De Pont
Publikováno v:
Biochimica et Biophysica Acta. Biomembranes, 1669, 61-8
Biochimica et Biophysica Acta. Biomembranes, 1669, 1, pp. 61-8
Biochimica et Biophysica Acta. Biomembranes, 1669, 1, pp. 61-8
Contains fulltext : 48917.pdf (Publisher’s version ) (Closed access) The Na,K-ATPase is an ion-translocating transmembrane protein that actively maintains the electrochemical gradients for Na+ and K+ across the plasma membrane. The functional prote
Autor:
Eva Grabsch, Sven Geibel, Ernst Bamberg, Thomas Friedrich, Jan Joep H.H.M. De Pont, Jan B. Koenderink
Publikováno v:
Journal of Biological Chemistry, 278, 51, pp. 51213-22
Journal of Biological Chemistry, 278, 51213-22
Journal of Biological Chemistry, 278, 51213-22
Contains fulltext : 142631.pdf (Publisher’s version ) (Open Access) Na,K-ATPase mediates net electrogenic transport by extruding three Na+ ions and importing two K+ ions across the plasma membrane during each reaction cycle. We mutated putative cat
Publikováno v:
Biochimica et Biophysica Acta. Biomembranes, 1838, 1693-700
Biochimica et Biophysica Acta. Biomembranes, 1838, 7, pp. 1693-700
Biochimica et Biophysica Acta. Biomembranes, 1838, 7, pp. 1693-700
Contains fulltext : 133904.pdf (Publisher’s version ) (Closed access) Sporadic hemiplegic migraine type 2 (SHM2) and familial hemiplegic migraine type 2 (FHM2) are rare forms of hemiplegic migraine caused by mutations in the Na(+),K(+)-ATPase alpha
Publikováno v:
Insect Biochemistry and Molecular Biology, 43, 1109-15
Insect Biochemistry and Molecular Biology, 43, 12, pp. 1109-15
Insect Biochemistry and Molecular Biology, 43, 12, pp. 1109-15
Item does not contain fulltext Mutagenesis analyses and a recent crystal structure of the mammalian Na,K-ATPase have identified amino acids which are responsible for high affinity binding of cardenolides (such as ouabain) which at higher doses block
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835c0cd715f9430f3119fb36a7eb0a94
http://hdl.handle.net/2066/125223
http://hdl.handle.net/2066/125223