Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Barbara Dunn"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 6, Pp 1899-1911 (2017)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Over its evolutionary history, Saccharomyces cerevisiae has evolved to be well-adapted to fluctuating nutrient availability. In the presence of sufficient nutrients, yeast cells continue to proliferate, but upon starvation haploid yeast cells enter s
Publikováno v:
Genetics
Creating Saccharomyces yeasts capable of efficient fermentation of pentoses such as xylose remains a key challenge in the production of ethanol from lignocellulosic biomass. Metabolic engineering of industrial Saccharomyces cerevisiae strains has yie
Autor:
Dmitri A. Petrov, Yuping Li, Daniel S. Fisher, Sandeep Venkataram, Gavin Sherlock, Barbara Dunn, Atish Agarwala
Publikováno v:
Current Biology. 28:515-525.e6
Summary Few studies have "quantitatively" probed how adaptive mutations result in increased fitness. Even in simple microbial evolution experiments, with full knowledge of the underlying mutations and specific growth conditions, it is challenging to
Autor:
Kerry Geiler-Samerotte, Yuping Li, Jamie R. Blundell, Dmitri A. Petrov, Lucas Hérissant, Jessica Chang, Emily R. Ebel, Atish Agarwala, Barbara Dunn, Sandeep Venkataram, Gavin Sherlock, Sasha F. Levy, Daniel S. Fisher
Publikováno v:
Cell. 166:1585-1596.e22
Adaptive evolution plays a large role in generating the phenotypic diversity observed in nature, yet current methods are impractical for characterizing the molecular basis and fitness effects of large numbers of individual adaptive mutations. Here we
Publikováno v:
Molecular and Cellular Biology. 16:2545-2553
The presence of H2A-H2B dimers in nucleosomes can inhibit the binding of transcription factors to chromatin templates. To study the roles of histones H2A and H2B in transcriptional repression in vivo, mutant forms of these histones were analyzed in t
Autor:
Daoud Meerzaman, Lalage M. Wakefield, Barbara Dunn, Maxwell P. Lee, Misako Sato, Mitsutaka Kadota, Robert J. Clifford, Howard H. Yang, Bianca P. Gomez
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9201 (2010)
PLoS ONE
PLoS ONE
To gain insight into the role of genomic alterations in breast cancer progression, we conducted a comprehensive genetic characterization of a series of four cell lines derived from MCF10A. MCF10A is an immortalized mammary epithelial cell line (MEC);
Publikováno v:
Somatic cell and molecular genetics. 16(3)
In attempts to isolate new CHO glycosylation mutants, selection protocols using plant lectins that bind galactose residues of cell surface carbohydrates were applied to mutagenized CHO populations. The lectins were used alone or in combination to obt