Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anna Ciotkowska"'
Autor:
Bingsheng Li, Beata Rutz, Christian G. Stief, Annabel Spek, Raphaela Waidelich, Ru Huang, Anna Ciotkowska, Yuhan Liu, Martin Hennenberg, Frank Strittmatter, Ruixiao Wang
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology
Non-adrenergic prostate smooth muscle contractions may account for the limited effectiveness of α1-adrenoceptor antagonists, which are the first-line option for medical treatment of voiding symptoms suggestive of benign prostatic hyperplasia. In non
Autor:
Alexander, Tamalunas, Amin, Wendt, Florian, Springer, Victor, Vigodski, Anna, Ciotkowska, Beata, Rutz, Ruixiao, Wang, Ru, Huang, Yuhan, Liu, Heiko, Schulz, Stephan, Ledderose, Thomas, Kolben, Giuseppe, Magistro, Christian G, Stief, Martin, Hennenberg
Publikováno v:
Life Sciences. 308:120931
Recently, the European Association of Urology recommended hexane-extracted fruit of Serenoa repens (HESr) in their guidelines on management of non-neurogenic male lower urinary tracts symptoms (LUTS). Despite previously lacking recommendations, Permi
Autor:
Ruixiao Wang, Alexander Tamalunas, Christian G. Stief, Beata Rutz, Bingsheng Li, Cora Sauckel, Ru Huang, Anna Ciotkowska, Martin Hennenberg, Christian Gratzke
Publikováno v:
Life sciences. 281
Aims Medical treatment for lower urinary tract symptoms secondary to benign prostatic hyperplasia is characterized by an unfavorable balance between limited efficacy and pronounced side effects. We recently reported, that thalidomide reduces prostate
Autor:
Annika Herlemann, Christian Gratzke, Christian G. Stief, Beata Rutz, Raphaela Waidelich, Paul Kuppermann, Martin Hennenberg, Yiming Wang, Alexander Tamalunas, Anna Ciotkowska, Bingsheng Li, Xiaolong Wang, Qingfeng Yu, Frank Strittmatter, Ruixiao Wang
Publikováno v:
J Biol Chem
Voiding symptoms in benign prostatic hyperplasia (BPH) are driven by prostate smooth muscle contraction and prostate growth. Smooth muscle contraction in the prostate and other organs critically depends on activation of the small monomeric GTPase Rho
Autor:
Cora Sauckel, Ru Huang, Ruixiao Wang, Bingsheng Li, Martin Hennenberg, Anna Ciotkowska, Christian Gratzke, Alexander Tamalunas, Christian G. Stief, Beata Rutz
Publikováno v:
The ProstateREFERENCES. 81(7)
Background Medical treatment in benign prostatic hyperplasia targets prostate size to prevent disease progression, complications, and surgery, and prostate smooth muscle tone for rapid relief of lower urinary tract symptoms. Combination therapies are
Autor:
Bingsheng, Li, Xiaolong, Wang, Ruixiao, Wang, Beata, Rutz, Anna, Ciotkowska, Christian, Gratzke, Annika, Herlemann, Annabel, Spek, Alexander, Tamalunas, Raphaela, Waidelich, Christian G, Stief, Martin, Hennenberg
Publikováno v:
The ProstateREFERENCES. 80(11)
Prostate smooth muscle contraction is critical for etiology and treatment of lower urinary tract symptoms in benign prostatic hyperplasia (BPH). Integrins connect the cytoskeleton to membranes and cells to extracellular matrix, what is essential for
Autor:
Beata Rutz, Yiming Wang, Alexander Tamalunas, Christian G. Stief, Melanie Schott, Annika Herlemann, Christian Gratzke, Frank Strittmatter, Anna Ciotkowska, Patrick Keller, Martin Hennenberg, Raphaela Waidelich, Qingfeng Yu
Publikováno v:
American Journal of Physiology-Renal Physiology. 314:F47-F57
Prostate smooth muscle contraction is critical for etiology and treatment of male lower urinary tract symptoms (LUTS) and is promoted by small monomeric GTPases (RhoA and Rac). GTPases may be activated by guanosine nucleotide exchange factors (GEFs).
Autor:
Alexander Tamalunas, Annika Herlemann, Beata Rutz, Melanie Schott, Christian G. Stief, Anna Ciotkowska, Qingfeng Yu, Frank Strittmatter, Christian Gratzke, Patrick Keller, Martin Hennenberg, Yiming Wang
Publikováno v:
European Journal of Pharmacology. 803:39-47
Male lower urinary tract symptoms (LUTS) due to bladder outlet obstruction are characterized by abnormal smooth muscle contractions in the lower urinary tract. Alpha1-adrenoceptor antagonists may induce smooth muscle relaxation in the outflow region
Autor:
Xiaolong, Wang, Bingsheng, Li, Anna, Ciotkowska, Beata, Rutz, Mark G, Erlander, Maya, Ridinger, Ruixiao, Wang, Alexander, Tamalunas, Raphaela, Waidelich, Christian G, Stief, Martin, Hennenberg
Publikováno v:
European journal of pharmacology. 873
Prostate smooth muscle contraction and prostate enlargement contribute to lower urinary tract symptoms suggestive of benign prostatic hyperplasia. Recent evidence demonstrated that inhibitors for polo-like kinases (PLKs) inhibit smooth muscle contrac
Autor:
Beata Rutz, Frank Strittmatter, Christian G. Stief, Martin Hennenberg, Christian Gratzke, Bingsheng Li, Xiaolong Wang, Chunxiao Liu, Annika Herlemann, Yiming Wang, Alexander Tamalunas, Christian Sterr, Qingfeng Yu, Anna Ciotkowska, Raphaela Waidelich
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Epidemiologic studies revealed a context between lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) and metabolic syndrome. However, molecular mechanisms underlying this relationship are largely unknown. Prostate enl