Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Wayne B. Anderson"'
Publikováno v:
Proceedings of the National Academy of Sciences. 110:15800-15805
The dorsal raphe nucleus (DR) controls forebrain serotonin neurotransmission to influence emotional states. GABA neurotransmission in the DR has been implicated in regulating sleep/wake states and influencing anxiety and aggression. To gain insight i
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 92(5)
Protein kinase C (PKC) is a multigene family of serine/threonine kinases that are central to many signal transduction pathways. Among the PKC isozymes, only PKC epsilon has been reported to exhibit full oncogenic potential. PKC epsilon also displays
Publikováno v:
Proceedings of the National Academy of Sciences. 70:3802-3805
To investigate how cell population density influences the intracellular concentration of cyclic AMP we have measured adenylate cyclase and cyclic AMP phosphodiesterase activities and cyclic AMP levels at various stages of cell density in normal rat-k
Publikováno v:
Proceedings of the National Academy of Sciences. 86:6758-6762
The susceptibility of purified protein kinase C to oxidative inactivation by H2O2 was found to be increased by Ca2+ either alone at a high (5 mM) concentration or at a low (approximately 50 microM) concentration along with phosphatidylserine and diac
Publikováno v:
Proceedings of the National Academy of Sciences. 67:1417-1424
Regulation of glutamine synthetase (EC 6.3.1.2) in Escherichia coli is mediated by adenylylation and deadenylylation of the enzyme. The present studies show that one protein is a common component of both the adenylylation and deadenylylation systems.
Autor:
Wayne B. Anderson, William L. Farrar
Publikováno v:
Nature. 315:233-235
Interleukin-2 (IL-2) is a regulatory peptide important for the growth and differentiation of antigen-specific T lymphocytes and large granular lymphocytes. Interaction of IL-2 with its specific receptor results in the promotion of S-phase progression
Publikováno v:
Nature. 315:235-237
Interleukin-3 (IL-3) is a member of a family of growth and differentiation peptides, collectively referred to as colony-stimulating factors, which regulate haematopoiesis. IL-3 has been highly purified from medium conditioned by WEHI-3B cells, and re
Publikováno v:
Nature. 314(6009)
The pineal gland has proven to be an excellent model for the study of adrenergic control systems. Noradrenaline, released from sympathetic nerve terminals in the pineal gland, regulates a large nocturnal increase in melatonin synthesis by stimulating
Autor:
Wayne B. Anderson, Andrew S. Kraft
Publikováno v:
Nature. 301(5901)
Although the biochemical mechanism of action of phorbol ester tumour promoters is not fully understood, it is known that phorbol ester binding to the cell surface causes rapid changes in calcium flux1,2 and phospholipid metabolism3–7. A protein kin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 76(8)
The adenylate cyclase activity [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] of crude Chinese hamster ovary cell membranes was inhibited 30-40% by low concentrations (6-600 ng/ml) of calcium-dependent regulator (CDR). This inhibitory effect was l