Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Manabu, Igarashi"'
Autor:
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H. Christensen, Yonas M. Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian I. Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate M. Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa E. Müller, Manabu Igarashi, Hiroki Kato
Publikováno v:
Tsukamoto, Y, Hiono, T, Yamada, S, Matsuno, K, Faist, A, Claff, T, Hou, J, Namasivayam, V, vom Hemdt, A, Sugimoto, S, Ng, J Y, Christensen, M H, Tesfamariam, Y M, Wolter, S, Juranek, S, Zillinger, T, Bauer, S, Hirokawa, T, Schmidt, F I, Kochs, G, Shimojima, M, Huang, Y S, Pichlmair, A, Kümmerer, B M, Sakoda, Y, Schlee, M, Brunotte, L, Müller, C E, Igarashi, M & Kato, H 2023, ' Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication ', Science, vol. 379, no. 6632, pp. 586-591 . https://doi.org/10.1126/science.add0875
Orthomyxo- and bunyaviruses steal the 5′ cap portion of host RNAs to prime their own transcription in a process called “cap snatching.” We report that RNA modification of the cap portion by host 2′-O-ribose methyltransferase 1 (MTr1) is essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ca613036512c6c980ca13774bda357
https://pure.au.dk/portal/da/publications/inhibition-of-cellular-rna-methyltransferase-abrogates-influenza-virus-capping-and-replication(e57afff0-1209-4d3e-92f4-f592420aad55).html
https://pure.au.dk/portal/da/publications/inhibition-of-cellular-rna-methyltransferase-abrogates-influenza-virus-capping-and-replication(e57afff0-1209-4d3e-92f4-f592420aad55).html
Autor:
Yoko Fujita-Fujiharu, Yukihiko Sugita, Yuki Takamatsu, Kazuya Houri, Manabu Igarashi, Yukiko Muramoto, Masahiro Nakano, Yugo Tsunoda, Ichiro Taniguchi, Stephan Becker, Takeshi Noda
Publikováno v:
Nature communications. 13(1)
The nucleoprotein (NP) of Marburg virus (MARV), a close relative of Ebola virus (EBOV), encapsidates the single-stranded, negative-sense viral genomic RNA (vRNA) to form the helical NP–RNA complex. The NP–RNA complex constitutes the core structur
Autor:
Hiroko Miyamoto, Ayato Takada, Reiko Yoshida, Rashid Manzoor, Yoshihiro Takadate, Masahiro Kajihara, Junki Maruyama, Hirohito Ogawa, Wakako Furuyama, Tatsunari Kondoh, Masahiro Sato, Naganori Nao, Manabu Igarashi
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Two novel influenza A virus-like genomes were detected in fruit bats in Central and South America. However, the biological properties of these bat-derived influenza viruses (BatIVs) are still largely unknown since infectious viral particles have neve
Autor:
Hiroko Miyamoto, Wakako Furuyama, Osamu Noyori, Ayato Takada, Asuka Nanbo, Heinz Feldmann, Junki Maruyama, Elaine Haddock, Manabu Igarashi, Reiko Yoshida, Andrea Marzi
Publikováno v:
Scientific Reports
During the latest outbreak of Ebola virus disease in West Africa, monoclonal antibody therapy (e.g., ZMapp) was utilized to treat patients. However, due to the antigenic differences among the five ebolavirus species, the current therapeutic monoclona
Autor:
Ayano Meguro, Kenji S. Nakahara, Jun Shao, Takeshi Matsumura, Manabu Igarashi, Chikara Masuta, Kazunori Goto, Syouta Yamada, Noriko Itchoda, Ichiro Uyeda, Kazuki Tadamura, Kae Sueda, Richard W. Carthew, Toru Sekiguchi, Tomoko S. Wada, Kimihito Ito, Yukiko Kashihara, Hanako Shimura
Publikováno v:
Proceedings of the National Academy of Sciences. 109:10113-10118
RNA silencing (RNAi) induced by virus-derived double-stranded RNA (dsRNA), which is in a sense regarded as a pathogen-associated molecular pattern (PAMP) of viruses, is a general plant defense mechanism. To counteract this defense, plant viruses expr
Autor:
Naganori Nao, Makoto Kuroda, Keita Matsuno, Ayato Takada, Daisuke Fujikura, Wakako Furuyama, Asako Shigeno, Manabu Igarashi, Rashid Manzoor, Reiko Yoshida, Masahiro Kajihara, Tatsunari Kondoh, Junki Maruyama, Hiroko Miyamoto
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186450 (2017)
PLoS ONE, Vol 12, Iss 10, p e0186450 (2017)
It has been proposed that some non-retroviral RNA virus genes are integrated into vertebrate genomes. Endogenous filovirus-like elements (EFLs) have been discovered in some mammalian genomes. However, their potential roles in ebolavirus infection are
Autor:
Shintaro Kobayashi, Keita Nagakawa, Kenichi Niikura, Hirofumi Sawa, Tadaki Suzuki, Manabu Igarashi, Noriko Ohtake, Yasuko Orba, Harumi Kasamatsu, Takashi Kimura
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 10, p e76668 (2013)
PLoS ONE, Vol 8, Iss 10, p e76668 (2013)
The capsid of the human polyomavirus JC virus (JCV) consists of 72 pentameric capsomeres of a major structural protein, Vp1. The cysteine residues of the related Vp1 of SV40 are known to contribute to Vp1 folding, pentamer formation, pentamer-pentame
Autor:
Mohamad Amin, Syafril Daulay, Reiko Yoshida, Eri Nakayama, Manabu Igarashi, Hiroko Miyamoto, Indi N. L. P. Dharmayanti, Chairul A. Nidom, Ayato Takada, Yoes Prijatna Dachlan, Mohamad Y. Alamudi, Reviany V. Nidom
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40740 (2012)
PLoS ONE
PLoS ONE
Ebola virus (EBOV) and Marburg virus (MARV) belong to the family Filoviridae and cause severe hemorrhagic fever in humans and nonhuman primates. Despite the discovery of EBOV (Reston virus) in nonhuman primates and domestic pigs in the Philippines an
Autor:
Manabu Igarashi, Hiroshi Kida, Kimihito Ito, Yutaka Miyazaki, Syaka Iida, Ayato Takada, Teiji Murakami
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 10, p e25953 (2011)
PLoS ONE, Vol 6, Iss 10, p e25953 (2011)
Human influenza A viruses undergo antigenic changes with gradual accumulation of amino acid substitutions on the hemagglutinin (HA) molecule. A strong antigenic mismatch between vaccine and epidemic strains often requires the replacement of influenza
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 2, p e57684 (2013)
PLoS ONE, Vol 8, Iss 2, p e57684 (2013)
A large number of nucleotide sequences of various pathogens are available in public databases. The growth of the datasets has resulted in an enormous increase in computational costs. Moreover, due to differences in surveillance activities, the number