Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jennifer A. Wargo"'
Autor:
Joon Seok Park, Francesca S. Gazzaniga, Meng Wu, Amalia K. Luthens, Jacob Gillis, Wen Zheng, Martin W. LaFleur, Sarah B. Johnson, Golnaz Morad, Elizabeth M. Park, Yifan Zhou, Stephanie S. Watowich, Jennifer A. Wargo, Gordon J. Freeman, Dennis L. Kasper, Arlene H. Sharpe
Publikováno v:
Nature. 617:377-385
Autor:
Miles C. Andrews, Junna Oba, Chang-Jiun Wu, Haifeng Zhu, Tatiana Karpinets, Caitlin A. Creasy, Marie-Andrée Forget, Xiaoxing Yu, Xingzhi Song, Xizeng Mao, A. Gordon Robertson, Gabriele Romano, Peng Li, Elizabeth M. Burton, Yiling Lu, Robert Szczepaniak Sloane, Khalida M. Wani, Kunal Rai, Alexander J. Lazar, Lauren E. Haydu, Matias A. Bustos, Jianjun Shen, Yueping Chen, Margaret B. Morgan, Jennifer A. Wargo, Lawrence N. Kwong, Cara L. Haymaker, Elizabeth A. Grimm, Patrick Hwu, Dave S. B. Hoon, Jianhua Zhang, Jeffrey E. Gershenwald, Michael A. Davies, P. Andrew Futreal, Chantale Bernatchez, Scott E. Woodman
Publikováno v:
Nature Communications. 13
Melanoma cells display distinct intrinsic phenotypic states. Here, we seek to characterize the molecular regulation of these states using multi-omic analyses of whole exome, transcriptome, microRNA, long non-coding RNA and DNA methylation data togeth
Autor:
Rodabe N. Amaria, Michael Postow, Elizabeth M. Burton, Michael T. Tetzlaff, Merrick I. Ross, Carlos Torres-Cabala, Isabella C. Glitza, Fei Duan, Denái R. Milton, Klaus Busam, Lauren Simpson, Jennifer L. McQuade, Michael K. Wong, Jeffrey E. Gershenwald, Jeffrey E. Lee, Ryan P. Goepfert, Emily Z. Keung, Sarah B. Fisher, Allison Betof-Warner, Alexander N. Shoushtari, Margaret Callahan, Daniel Coit, Edmund K. Bartlett, Danielle Bello, Parisa Momtaz, Courtney Nicholas, Aidi Gu, Xuejun Zhang, Brinda Rao Korivi, Madhavi Patnana, Sapna P. Patel, Adi Diab, Anthony Lucci, Victor G. Prieto, Michael A. Davies, James P. Allison, Padmanee Sharma, Jennifer A. Wargo, Charlotte Ariyan, Hussein A. Tawbi
Publikováno v:
Nature. 615:E23-E23
Autor:
Rodabe N. Amaria, Michael Postow, Elizabeth M. Burton, Michael T. Tetzlaff, Merrick I. Ross, Carlos Torres-Cabala, Isabella C. Glitza, Fei Duan, Denái R. Milton, Klaus Busam, Lauren Simpson, Jennifer L. McQuade, Michael K. Wong, Jeffrey E. Gershenwald, Jeffrey E. Lee, Ryan P. Goepfert, Emily Z. Keung, Sarah B. Fisher, Allison Betof-Warner, Alexander N. Shoushtari, Margaret Callahan, Daniel Coit, Edmund K. Bartlett, Danielle Bello, Parisa Momtaz, Courtney Nicholas, Aidi Gu, Xuejun Zhang, Brinda Rao Korivi, Madhavi Patnana, Sapna P. Patel, Adi Diab, Anthony Lucci, Victor G. Prieto, Michael A. Davies, James P. Allison, Padmanee Sharma, Jennifer A. Wargo, Charlotte Ariyan, Hussein A. Tawbi
Publikováno v:
Nature. 611(7934)
Relatlimab and nivolumab combination immunotherapy improves progression-free survival over nivolumab monotherapy in patients with unresectable advanced melanoma1. We investigated this regimen in patients with resectable clinical stage III or oligomet
Autor:
Oren Ziv, Nadim J. Ajami, Jacob Schachter, Yael Steinberg-Silman, Camila Avivi, Rona Ortenberg, Lior H. Katz, Stephen P. Raskin, Moran Amit, Yael Eshet, Abdul Wadud Khan, Nethanel Asher, Jennifer A. Wargo, Ilan Youngster, Ronnie Shapira-Frommer, Liat Anafi, Shira Ben-Simon, Iris Barshack, Omry Koren, Gal Markel, Tal Brosh-Nissimov, Guy Ben-Betzalel, Katerina Adler, Daniil Rotin, Ronac Mamtani, Jenny Melnichenko, Hagit Harati, Ben Boursi, Adi Lahat, Erez N. Baruch, Daniela Dick-Necula, Naamah Bloch
Publikováno v:
Science. 371:602-609
New fecal microbiota for cancer patients The composition of the gut microbiome influences the response of cancer patients to immunotherapies. Baruch et al. and Davar et al. report first-in-human clinical trials to test whether fecal microbiota transp
Autor:
Christopher P. Vellano, Michael G. White, Miles C. Andrews, Manoj Chelvanambi, Russell G. Witt, Joseph R. Daniele, Mark Titus, Jennifer L. McQuade, Fabio Conforti, Elizabeth M. Burton, Matthew J. Lastrapes, Gabriel Ologun, Alexandria P. Cogdill, Golnaz Morad, Peter Prieto, Alexander J. Lazar, Yanshuo Chu, Guangchun Han, M. A. Wadud Khan, Beth Helmink, Michael A. Davies, Rodabe N. Amaria, Jeffrey J. Kovacs, Scott E. Woodman, Sapna Patel, Patrick Hwu, Michael Peoples, Jeffrey E. Lee, Zachary A. Cooper, Haifeng Zhu, Guang Gao, Hiya Banerjee, Mike Lau, Jeffrey E. Gershenwald, Anthony Lucci, Emily Z. Keung, Merrick I. Ross, Laura Pala, Eleonora Pagan, Rossana Lazcano Segura, Qian Liu, Mikayla S. Borthwick, Eric Lau, Melinda S. Yates, Shannon N. Westin, Khalida Wani, Michael T. Tetzlaff, Lauren E. Haydu, Mikhila Mahendra, XiaoYan Ma, Christopher Logothetis, Zachary Kulstad, Sarah Johnson, Courtney W. Hudgens, Ningping Feng, Lorenzo Federico, Georgina V. Long, P. Andrew Futreal, Swathi Arur, Hussein A. Tawbi, Amy E. Moran, Linghua Wang, Timothy P. Heffernan, Joseph R. Marszalek, Jennifer A. Wargo
Publikováno v:
Nature. 613:E3-E3
Autor:
Christine N. Spencer, Jennifer L. McQuade, Vancheswaran Gopalakrishnan, John A. McCulloch, Marie Vetizou, Alexandria P. Cogdill, Md A. Wadud Khan, Xiaotao Zhang, Michael G. White, Christine B. Peterson, Matthew C. Wong, Golnaz Morad, Theresa Rodgers, Jonathan H. Badger, Beth A. Helmink, Miles C. Andrews, Richard R. Rodrigues, Andrey Morgun, Young S. Kim, Jason Roszik, Kristi L. Hoffman, Jiali Zheng, Yifan Zhou, Yusra B. Medik, Laura M. Kahn, Sarah Johnson, Courtney W. Hudgens, Khalida Wani, Pierre-Olivier Gaudreau, Angela L. Harris, Mohamed A. Jamal, Erez N. Baruch, Eva Perez-Guijarro, Chi-Ping Day, Glenn Merlino, Barbara Pazdrak, Brooke S. Lochmann, Robert A. Szczepaniak-Sloane, Reetakshi Arora, Jaime Anderson, Chrystia M. Zobniw, Eliza Posada, Elizabeth Sirmans, Julie Simon, Lauren E. Haydu, Elizabeth M. Burton, Linghua Wang, Minghao Dang, Karen Clise-Dwyer, Sarah Schneider, Thomas Chapman, Nana-Ama A. S. Anang, Sheila Duncan, Joseph Toker, Jared C. Malke, Isabella C. Glitza, Rodabe N. Amaria, Hussein A. Tawbi, Adi Diab, Michael K. Wong, Sapna P. Patel, Scott E. Woodman, Michael A. Davies, Merrick I. Ross, Jeffrey E. Gershenwald, Jeffrey E. Lee, Patrick Hwu, Vanessa Jensen, Yardena Samuels, Ravid Straussman, Nadim J. Ajami, Kelly C. Nelson, Luigi Nezi, Joseph F. Petrosino, P. Andrew Futreal, Alexander J. Lazar, Jianhua Hu, Robert R. Jenq, Michael T. Tetzlaff, Yan Yan, Wendy S. Garrett, Curtis Huttenhower, Padmanee Sharma, Stephanie S. Watowich, James P. Allison, Lorenzo Cohen, Giorgio Trinchieri, Carrie R. Daniel, Jennifer A. Wargo
Publikováno v:
Science (New York, N.Y.). 374(6575)
Another benefit of dietary fiber The gut microbiome can modulate the immune system and influence the therapeutic response of cancer patients, yet the mechanisms underlying the effects of microbiota are presently unclear. Spencer et al . add to our un
Autor:
Paul Lorigan, Rohit Thakur, Miles C. Andrews, Kate Hogan, Piyushkumar A. Mundra, Richard Marais, Martin G. Cook, Kang Zeng, Louis Boon, Antonia Banyard, Nathalie Dhomen, Matthew Smith, Jennifer A. Wargo, Jonathan Greenall, Elena Galvani, Garry Ashton, A. Mandal, Beth A. Helmink, Pablo Garcia-Martinez, Gabriela Gremel, Christopher P. E. Chester, Sara Valpione
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Galvani, E, Mundra, P A, Valpione, S, Garcia-Martinez, P, Smith, M, Greenall, J, Thakur, R, Helmink, B, Andrews, M C, Boon, L, Chester, C, Gremel, G, Hogan, K, Mandal, A, Zeng, K, Banyard, A, Ashton, G, Cook, M, Lorigan, P, Wargo, J A, Dhomen, N & Marais, R 2020, ' Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma ', Nature Communications, vol. 11, no. 1, pp. 853 . https://doi.org/10.1038/s41467-020-14632-2
Nature Communications
Galvani, E, Mundra, P A, Valpione, S, Garcia-Martinez, P, Smith, M, Greenall, J, Thakur, R, Helmink, B, Andrews, M C, Boon, L, Chester, C, Gremel, G, Hogan, K, Mandal, A, Zeng, K, Banyard, A, Ashton, G, Cook, M, Lorigan, P, Wargo, J A, Dhomen, N & Marais, R 2020, ' Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma ', Nature Communications, vol. 11, no. 1, pp. 853 . https://doi.org/10.1038/s41467-020-14632-2
Nature Communications
Although immune checkpoint inhibitors (ICIs) have achieved unprecedented results in melanoma, the biological features of the durable responses initiated by these drugs remain unknown. Here we show the genetic and phenotypic changes induced by treatme
Autor:
Jianjun Gao, Hao Zhao, Rebecca S. S. Tidwell, Emily Z. Keung, Yuji Miura, Salahaldin A. Tahir, Sumit K. Subudhi, Hussein Abdul-Hassan Tawbi, Jennifer A. Wargo, James P. Allison, Padmanee Sharma, Jorge Blando
Publikováno v:
Proceedings of the National Academy of Sciences. 116:22246-22251
Immune checkpoint (IC) therapy provides substantial benefits to cancer patients but can also cause distinctive toxicities termed immune-related adverse events (irAEs). Biomarkers to predict toxicities will be necessary to improve management of patien
Autor:
Timothy F. Cloughesy, Yue Lu, James R. Heath, Frances Chow, Richard Everson, Robert M. Prins, Michael T. Tetzlaff, Jennifer A. Wargo, Alphonsus H. C. Ng, Rohit Thakur, Beth A. Helmink
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The response of patients with recurrent glioblastoma multiforme to neoadjuvant immune checkpoint blockade has been challenging to interpret due to the inter-patient and intra-tumor heterogeneity. We report on a comparative analysis of tumor tissues c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f007076811a2b3d9771fde1cbbaa92af
https://escholarship.org/uc/item/3bm882sp
https://escholarship.org/uc/item/3bm882sp