Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Jan Tavernier"'
Autor:
Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr
Publikováno v:
Nature Communications. 14
Generating reference maps of interactome networks illuminates genetic studies by providing a protein-centric approach to finding new components of existing pathways, complexes, and processes. We apply state-of-the-art methods to identify binary prote
Autor:
Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva
Publikováno v:
Nature Communications. 14
Autor:
Shengru Pang, Anje Cauwels, Sandra Van Lint, Marco Prinz, Niko Kley, Elke Rogge, Jan Tavernier, Bram Van Den Eeckhout, Gilles Uzé, Annick Verhee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11, ⟨10.1038/s41598-021-00891-6⟩
SCIENTIFIC REPORTS
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11, ⟨10.1038/s41598-021-00891-6⟩
SCIENTIFIC REPORTS
Type I Interferon (IFN) was the very first drug approved for the treatment of Multiple Sclerosis (MS), and is still frequently used as a first line therapy. However, systemic IFN also causes considerable side effects, affecting therapy adherence and
Autor:
David J. Pagliarini, Kritika Bhalla, Karen Rosier, Brendan J. Floyd, Rudy Van Coster, John W.M. Creemers, Irma Lemmens, Edrees H. Rashan, Maxime Verschoore, Benjamin F. Cravatt, Matteo Dal Peraro, Katlijn Vints, Luc Régal, Joél Smet, Laetitia Aerts, Arnaud Vanlander, Yenthe Monnens, Natalia V. Gounko, Craig A. Bingman, Jan Tavernier, Molly T. McDevitt, Maria J. Marcaida
Publikováno v:
iScience
ISCIENCE
iScience, Vol 24, Iss 12, Pp 103460-(2021)
ISCIENCE
iScience, Vol 24, Iss 12, Pp 103460-(2021)
Summary Deficiency of the serine hydrolase prolyl endopeptidase-like (PREPL) causes a recessive metabolic disorder characterized by neonatal hypotonia, feeding difficulties, and growth hormone deficiency. The pathophysiology of PREPL deficiency and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d632ef57ff0933bdaa806f554927a20
https://hdl.handle.net/20.500.14017/c7bfdaf7-1b1c-4a72-9f07-6f40a36a6606
https://hdl.handle.net/20.500.14017/c7bfdaf7-1b1c-4a72-9f07-6f40a36a6606
Autor:
Eyal Simonovsky, Joseph C. Mellor, Amélie Dricot, Marc Vidal, Liana Goehring, Miquel Duran-Frigola, Florian Goebels, Dayag Sheykhkarimli, Thomas Rolland, Murat Tasan, John Rasla, Steffi De Rouck, Carles Pons, Sadie Schlabach, Yoseph Kassa, Claudia Colabella, Dong-Sic Choi, Yves Jacob, Joseph N. Paulson, Javier De Las Rivas, Madeleine F. Hardy, Francisco J. Campos-Laborie, Xinping Yang, Soon Gang Choi, Frederick P. Roth, Kerstin Spirohn, Nishka Kishore, Luke Lambourne, Cassandra D’Amata, Dawit Balcha, Adriana San-Miguel, Anupama Yadav, Anjali Gopal, Suet-Feung Chin, Suzanne Gaudet, Yang Wang, István Kovács, Elodie Hatchi, Natascha van Lieshout, Michael A. Calderwood, Yu Xia, Gloria M. Sheynkman, Robert J. Weatheritt, Marinella Gebbia, Atina G. Cote, Bridget E. Begg, Mohamed Helmy, Katja Luck, Bridget Teeking, Quan Zhong, Serena Landini, David E. Hill, Sudharshan Rangarajan, Georges Coppin, Ghazal Haddad, Omer Basha, Carl Pollis, Dylan Markey, Alice Desbuleux, Hanane Ennajdaoui, Dae-Kyum Kim, Vincent Tropepe, Roujia Li, Steven Deimling, Jennifer J. Knapp, Jan Tavernier, Mariana Babor, Benoit Charloteaux, Gary D. Bader, Alexander O. Tejeda, Aaron Richardson, Ruth Brignall, Ashyad Rayhan, Irma Lemmens, Tong Hao, Christian Bowman-Colin, Janusz Rak, David De Ridder, Jochen Weile, Wenting Bian, Jean-Claude Twizere, Patrick Aloy, Esti Yeger-Lotem, Meaghan Daley, Tiziana M. Cafarelli, Andrew MacWilliams, Miles W. Mee, Yun Shen
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature
Nature, Nature Publishing Group, 2020, 580 (7803), pp.402-408. ⟨10.1038/s41586-020-2188-x⟩
Nature, 2020, 580 (7803), pp.402-408. ⟨10.1038/s41586-020-2188-x⟩
instname
Nature
Nature, Nature Publishing Group, 2020, 580 (7803), pp.402-408. ⟨10.1038/s41586-020-2188-x⟩
Nature, 2020, 580 (7803), pp.402-408. ⟨10.1038/s41586-020-2188-x⟩
et al.
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype–phenotype relationships1,2. Here we present a human ‘all-by-all’ reference interact
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype–phenotype relationships1,2. Here we present a human ‘all-by-all’ reference interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faac39e9886775ddfef26fed76c6c35f
http://hdl.handle.net/10261/222715
http://hdl.handle.net/10261/222715
Autor:
Sudharshan Rangarajan, Philipp Trepte, Luke Lambourne, Soon Gang Choi, Patricia Cassonnet, Irma Lemmens, Javier De Las Rivas, Tong Hao, Wenting Bian, Marc Vidal, Eloi P. Coutant, Pierre-Olivier Vidalain, David E. Hill, Caroline Demeret, Mélanie Dos Santos, Michael A. Calderwood, Louis Jones, Julien Olivet, Kerstin Spirohn, Sylvie van der Werf, Erich E. Wanker, Jan Tavernier, Yves Jacob, Yves L. Janin, Jean-Claude Twizere, Katja Luck
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.3907. ⟨10.1038/s41467-019-11809-2⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, 2019, 10 (1), pp.3907. ⟨10.1038/s41467-019-11809-2⟩
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.3907. ⟨10.1038/s41467-019-11809-2⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, 2019, 10 (1), pp.3907. ⟨10.1038/s41467-019-11809-2⟩
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
© The Author(s) 2019.
Complementary assays are required to comprehensively map complex biological entities such as genomes, proteomes and interactome networks. However, how various assays can be optimally combined to approach completeness while
Complementary assays are required to comprehensively map complex biological entities such as genomes, proteomes and interactome networks. However, how various assays can be optimally combined to approach completeness while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f2bbfd1a267b0f3742fc7c507d912a
https://hal-pasteur.archives-ouvertes.fr/pasteur-02322138
https://hal-pasteur.archives-ouvertes.fr/pasteur-02322138
Autor:
José Van der Heyden, Karolien De Bosscher, Joris Wauman, Raffaele Mori, Laura Icardi, Jan Tavernier, Frank Peelman, Lode De Cauwer
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
SCIENTIFIC REPORTS
Scientific Reports
SCIENTIFIC REPORTS
Scientific Reports
STAT3 is a pleiotropic transcription factor involved in homeostatic and host defense processes in the human body. It is activated by numerous cytokines and growth factors and generates a series of cellular effects. Of the STAT-mediated signal transdu
Autor:
Geert van Loo, Rudi Beyaert, Kelly Van Looveren, Roman Vangoitsenhoven, Tineke Vanderhaeghen, Bart Van der Schueren, Jan Tavernier, Toshinori Nakayama, Sylviane Dewaele, Charlotte Wallaeys, Steven Timmermans, Claude Libert, Leen Catrysse, Lise Van Wyngene, Melanie Eggermont, Ioanna Petta, Katrien Corbeels, Jolien Vandewalle, Karolien De Bosscher
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102790-(2021)
ISCIENCE
iScience
ISCIENCE
iScience
Summary The hypothalamic-pituitary-adrenal (HPA) axis forms a complex neuroendocrine system that regulates the body’s response to stress such as starvation. In contrast with the glucocorticoid receptor (GR), Zinc finger and BTB domain containing 32
Autor:
Jan Tavernier, Dorien Clarisse, Karlien Van Wesemael, Ilse M. Beck, Fritz Offner, Karolien De Bosscher
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 5, p e0197000 (2018)
PLOS ONE
PLoS ONE, Vol 13, Iss 5, p e0197000 (2018)
PLOS ONE
Glucocorticoids (GCs) are a cornerstone in the treatment of lymphoid malignancies such as multiple myeloma (MM) and acute lymphoblastic leukemia (ALL). Yet, prolonged GC use is hampered by deleterious GC-related side effects and the emergence of GC r
Autor:
Jan Tavernier, Kenny Roose, Lien Van Hoecke, Alexander Van Parys, Xavier Saelens, Stefaan De Koker, Sandra Van Lint, Johan Grooten, Peter Vandenabeele
Publikováno v:
Cell Stress
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
NATURE COMMUNICATIONS
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
NATURE COMMUNICATIONS
Cancer immunotherapy can induce durable antitumor responses. However, many patients poorly respond to such therapies. Here we describe a generic antitumor therapy that is based on the intratumor delivery of mRNA that codes for the necroptosis executi