Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gurpanna Saggu"'
Autor:
Anu Autio, Gurpanna Saggu, Francisco E. Velázquez, Sara Rattik, Petr Jarolim, Daniel Engelbertsen, Andrew H. Lichtman, Robin A. F. Verwilligen, Francis W. Luscinskas, Gail Newton, Erik A. Levinsohn, Marie A.C. Depuydt, Huan Wang
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
CD47, also known as integrin-associated protein (IAP), is a transmembrane protein with multiple biological functions including regulation of efferocytosis and leukocyte trafficking. In this study we investigated the effect of CD47-deficiency on ather
Autor:
Florencia Rosetti, Ravi Vattepu, Suhail Tahir, Tanya N. Mayadas, Robert M. Anthony, Yunfeng Chen, Koshu Okubo, Nathaniel Washburn, Steven M. Holland, Cheng Zhu, Gurpanna Saggu, Aaron M. Rosado, Mehmet Sen, Naotake Tsuboi, Xavier Cullere
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Vascular-deposited IgG immune complexes promote neutrophil recruitment, but how this process is regulated is still unclear. Here we show that the CD18 integrin Mac-1, in its bent state, interacts with the IgG receptor FcγRIIA in cis to reduce the af
Autor:
Gurpanna Saggu, Lydia Sorokin, Benedikt Wirth, Paul Striewski, Jian Song, Huiyu Wang, Xueli Zhang, Klaus Ley, Konrad Buscher, Tanya N. Mayadas, Stefan Lütke-Enking
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Nature Communications
Nature Communications
Acute peritonitis is a frequent medical condition that can trigger severe sepsis as a life-threatening complication. Neutrophils are first-responders in infection but recruitment mechanisms to the abdominal cavity remain poorly defined. Here, we demo
Autor:
Saleh Alshamrani, Nicholas J. Lynch, Dimitrios Goundis, Bayad Mawlood Saeed, Robert B. Sim, Kashif Syed Haleem, Peter W. Andrew, Wilhelm J. Schwaeble, Hany I. Kenawy, Peter J. Lachmann, Viviana P. Ferreira, Azam Hayat, Youssif M. Ali, Anna Buchberger, Gurpanna Saggu
Modern medicine has established three central antimicrobial therapeutic concepts: vaccination, antibiotics, and, recently, the use of active immunotherapy to enhance the immune response toward specific pathogens. The efficacy of vaccination and antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a09603b8edb7d6e6db33be039687c3
https://europepmc.org/articles/PMC3986141/
https://europepmc.org/articles/PMC3986141/