Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Elliott Kieff"'
Autor:
Daisuke Okuzaki, Benjamin E. Gewurz, Hufeng Zhou, Hiroshi Kida, Masanori Obana, Elliott Kieff, Atsushi Kumanogoh, Yasushi Fujio, Teruhito Yasui, Chao-Yuan Tsai, Takeharu Minamitani, Bo Zhao, Yijie Ma, Hitoshi Kikutani
Publikováno v:
Proceedings of the National Academy of Sciences. 114:4751-4756
Epstein-Barr virus (EBV) is a major cause of immunosuppression-related B-cell lymphomas and Hodgkin lymphoma (HL). In these malignancies, EBV latent membrane protein 1 (LMP1) and LMP2A provide infected B cells with surrogate CD40 and B-cell receptor
Autor:
Yi Xin Zeng, Hufeng Zhou, Philippe Busson, Abdelmajid Khabir, Geng Xiong, Liangru Ke, Mu Sheng Zeng, George S.W. Tsao, Elliott Kieff, Bo Zhao, Yan-Qun Xiang, Yihong Ling, Xiang Guo, Chong Wang
Nasopharyngeal carcinoma (NPC) most frequently occurs in southern China and southeast Asia. Epidemiology studies link NPC to genetic predisposition, Epstein-Barr virus (EBV) infection, and environmental factors. Genetic studies indicate that mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227e9f28d1821c793392ceb8cbce0b37
https://europepmc.org/articles/PMC5594663/
https://europepmc.org/articles/PMC5594663/
Autor:
Tommy T. Shi, Bo Zhao, Anqi Wang, Bradford Willox, Amy M. Holthaus, Seiji Maruo, Peter V. Kharchenko, Sizun Jiang, Hufeng Zhou, Eric Johannsen, Elliott Kieff
Publikováno v:
Proceedings of the National Academy of Sciences. 111:421-426
Epstein-Barr virus nuclear antigen 3C (EBNA3C) repression of CDKN2A p14(ARF) and p16(INK4A) is essential for immortal human B-lymphoblastoid cell line (LCL) growth. EBNA3C ChIP-sequencing identified >13,000 EBNA3C sites in LCL DNA. Most EBNA3C sites
Autor:
Kentaro Morita, Elliott Kieff, Kaori Sakakibara-Yada, Hitoshi Kikutani, Taki Nishimura, Satoru Tada, George Mosialos, Teruhito Yasui
Publikováno v:
Proceedings of the National Academy of Sciences. 109:21022-21027
Germinal centers (GCs) are specialized microenvironments in secondary lymphoid organs where high-affinity antibody-producing B cells are selected based on B-cell antigen receptor (BCR) signal strength. BCR signaling required for normal GC selection i
Autor:
Ramnik J. Xavier, Bo Zhao, Fadi Towfic, Kaoru Takasaki, Nicholas P. Shinners, Jessica C. Mar, Elliott Kieff, Benjamin E. Gewurz, John Quackenbush, Ellen Cahir-McFarland
Publikováno v:
Proceedings of the National Academy of Sciences. 109:2467-2472
Although canonical NFκB is frequently critical for cell proliferation, survival, or differentiation, NFκB hyperactivation can cause malignant, inflammatory, or autoimmune disorders. Despite intensive study, mammalian NFκB pathway loss-of-function
Autor:
Elliott Kieff, John Quackenbush, Eric Johannsen, Jessica C. Mar, Chih Wen Peng, James Zou, Bo Zhao, Bradley E. Bernstein, Stephen C. Blacklow, Jon C. Aster, Matthew L. Freedman, Cynthia C. Morton, Hongfang Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 108:14902-14907
Epstein-Barr virus nuclear antigen 2 (EBNA2) regulation of transcription through the cell transcription factor RBPJ is essential for resting B-lymphocyte (RBL) conversion to immortal lymphoblast cell lines (LCLs). ChIP-seq of EBNA2 and RBPJ sites in
Autor:
Jon C. Aster, Hongfang Wang, Elliott Kieff, James Zou, Bradley E. Bernstein, Bo Zhao, Hoifung Wong, Todd Ashworth, Warren S. Pear, Jonathan Schug, Stephen C. Blacklow, Eric Johannsen, Kelly L. Arnett
Publikováno v:
Proceedings of the National Academy of Sciences. 108:14908-14913
Notch1 regulates gene expression by associating with the DNA-binding factor RBPJ and is oncogenic in murine and human T-cell progenitors. Using ChIP-Seq, we find that in human and murine T-lymphoblastic leukemia (TLL) genomes Notch1 binds preferentia
Publikováno v:
Proceedings of the National Academy of Sciences. 108:1919-1924
Epstein-Barr virus (EBV) nuclear antigen 3C (EBNA3C) and EBNA3A are each essential for EBV conversion of primary human B lymphocytes into continuously proliferating lymphoblast cell lines (LCLs) and for maintaining LCL growth. We now find that EBNA3C
Publikováno v:
Proceedings of the National Academy of Sciences. 106:4419-4424
Epstein-Barr virus (EBV) nuclear antigen 3C (EBNA3C) is essential for efficient conversion of primary human B lymphocytes to lymphoblastoid cell lines (LCLs) and for continued LCL growth. We used a transcomplementation assay in the context of LCLs tr
Autor:
Daisuke Okuzaki, Chiau-Yuang Tsai, Shuhei Sakakibara, Yijie Ma, Takeharu Minamitani, Hitoshi Kikutani, Benjamin E. Gewurz, Teruhito Yasui, Hufeng Zhou, Elliott Kieff
Epstein-Barr virus (EBV) infects germinal center (GC) B cells and establishes persistent infection in memory B cells. EBV-infected B cells can cause B-cell malignancies in humans with T- or natural killer-cell deficiency. We now find that EBV-encoded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454cb6133209454e54c0c4b8656c0e88
https://europepmc.org/articles/PMC4577157/
https://europepmc.org/articles/PMC4577157/